470. Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI) in Patients with Significant Drug Abuse: Outcomes from Global Phase 3 Studies of Delafloxacin (DLX)

por Overcash, J Scott, O’Riordan, William, Quintas, Megan, Lawrence, Laura, Tseng, Carol, Cammarata, Sue
Publicado 2019

1479. Clinical Efficacy and Safety Analysis Evaluating Oral Gepotidacin (GSK2140944) from a Phase IIa Study in the Treatment of Uncomplicated Urinary Tract Infections

por Overcash, J Scott, Dumont, Etienne, Perry, Caroline R, Tiffany, Courtney, Scangarella-Oman, Nicole, Raychaudhuri, Aparna, Hossain, Mohammad
Publicado 2019

Afabicin, a First-in-Class Antistaphylococcal Antibiotic, in the Treatment of Acute Bacterial Skin and Skin Structure Infections: Clinical Noninferiority to Vancomycin/Linezolid

por Wittke, Frederick, Vincent, Catherine, Chen, James, Heller, Barry, Kabler, Heidi, Overcash, J. Scott, Leylavergne, François, Dieppois, Guennaëlle
Publicado 2020

Pharmacokinetics, Safety, and Clinical Outcomes of Omadacycline in Women with Cystitis: Results from a Phase 1b Study

por Overcash, J. Scott, Bhiwandi, Pouru, Garrity-Ryan, Lynne, Steenbergen, Judith, Bai, Stephen, Chitra, Surya, Manley, Amy, Tzanis, Evan
Publicado 2019

Bone and Joint Tissue Penetration of the Staphylococcus-Selective Antibiotic Afabicin in Patients Undergoing Elective Hip Replacement Surgery

por Menetrey, Annick, Janin, Annick, Pullman, John, Overcash, J. Scott, Haouala, Amina, Leylavergne, François, Turbe, Laurent, Wittke, Frederick, Nicolas-Métral, Valérie
Publicado 2019

1687. Omadacycline in Female Adults With Acute Pyelonephritis: Results from a Randomized, Double-Blind, Adaptive Phase 2 Study

por Overcash, J Scott, Tzanis, Evan, Manley, Amy, Kirsch, Courtney, Serio, Alisa W, White, Tiffany, Wright, Kelly, Chitra, Surya, Eckburg, Paul B
Publicado 2020

1688. Omadacycline in Female Adults With Cystitis: Results From a Randomized, Double-Blinded, Adaptive Phase 2 Study

por Overcash, J Scott, Tzanis, Evan, Manley, Amy, Sirbu, Alissa, Serio, Alisa W, White, Tiffany, Wright, Kelly, Chitra, Surya, Eckburg, Paul B
Publicado 2020

Phase 2a Pharmacokinetic, Safety, and Exploratory Efficacy Evaluation of Oral Gepotidacin (GSK2140944) in Female Participants with Uncomplicated Urinary Tract Infection (Acute Unco...

por Overcash, J. Scott, Tiffany, Courtney A., Scangarella-Oman, Nicole E., Perry, Caroline R., Tao, Yu, Hossain, Mohammad, Barth, Aline, Dumont, Etienne F.
Publicado 2020

Ceftobiprole Compared With Vancomycin Plus Aztreonam in the Treatment of Acute Bacterial Skin and Skin Structure Infections: Results of a Phase 3, Randomized, Double-blind Trial (T...

por Overcash, J Scott, Kim, Charles, Keech, Richard, Gumenchuk, Illia, Ninov, Borislav, Gonzalez-Rojas, Yaneicy, Waters, Michael, Simeonov, Simeon, Engelhardt, Marc, Saulay, Mikael, Ionescu, Daniel, Smart, Jennifer I, Jones, Mark E, Hamed, Kamal A
Publicado 2020

Potent Antiviral Activities of the Direct-Acting Antivirals ABT-493 and ABT-530 with Three-Day Monotherapy for Hepatitis C Virus Genotype 1 Infection

por Lawitz, Eric J., O'Riordan, William D., Asatryan, Armen, Freilich, Bradley L., Box, Terry D., Overcash, J. Scott, Lovell, Sandra, Ng, Teresa I., Liu, Wei, Campbell, Andrew, Lin, Chih-Wei, Yao, Betty, Kort, Jens
Publicado 2016

Expanded Analysis of 20 Pneumococcal Serotypes Associated With Radiographically Confirmed Community-acquired Pneumonia in Hospitalized US Adults

por Isturiz, Raul, Grant, Lindsay, Gray, Sharon, Alexander-Parrish, Ronika, Jiang, Qin, Jodar, Luis, Peyrani, Paula, Ford, Kimbal D, Pride, Michael W, Self, Wesley H, Counselman, Francis, Volturo, Gregory, Ostrosky-Zeichner, Luis, Wunderink, Richard G, Sherwin, Robert, Overcash, J Scott, File, Thomas, Ramirez, Julio
Publicado 2021

Tocilizumab and remdesivir in hospitalized patients with severe COVID-19 pneumonia: a randomized clinical trial

por Rosas, Ivan O., Diaz, George, Gottlieb, Robert L., Lobo, Suzana M., Robinson, Philip, Hunter, Bradley D., Cavalcante, Adilson W., Overcash, J. Scott, Hanania, Nicola A., Skarbnik, Alan, Garcia-Diaz, Julia, Gordeev, Ivan, Carratalà, Jordi, Gordon, Oliver, Graham, Emily, Lewin-Koh, Nicholas, Tsai, Larry, Tuckwell, Katie, Cao, Huyen, Brainard, Diana, Olsson, Julie K.
Publicado 2021

Performance of PCR/Electrospray Ionization-Mass Spectrometry on Whole Blood for Detection of Bloodstream Microorganisms in Patients with Suspected Sepsis

por Strålin, Kristoffer, Rothman, Richard E., Özenci, Volkan, Barkataki, Kieron, Brealey, David, Dhiman, Neelam, Poling, Lara, Kurz, Michael C., Limaye, Ajit P., LoVecchio, Frank, Lowery, Kristin, Miller, Loren G., Moran, Gregory J., Overcash, J. Scott, Parekh, Amisha, Peacock, W. Frank, Rivers, Emanuel P., Sims, Matthew, Stubbs, Amy M., Sundqvist, Martin, Ullberg, Måns, Carroll, Karen C.
Publicado 2020

Randomized Clinical Trial on the Long-Term Efficacy and Safety of Lumasiran in Patients With Primary Hyperoxaluria Type 1

por Hulton, Sally A., Groothoff, Jaap W., Frishberg, Yaacov, Koren, Michael J., Overcash, J. Scott, Sellier-Leclerc, Anne-Laure, Shasha-Lavsky, Hadas, Saland, Jeffrey M., Hayes, Wesley, Magen, Daniella, Moochhala, Shabbir H., Coenen, Martin, Simkova, Eva, Garrelfs, Sander F., Sas, David J., Meliambro, Kristin A., Ngo, Taylor, Sweetser, Marianne T., Habtemariam, Bahru A., Gansner, John M., McGregor, Tracy L., Lieske, John C.
Publicado 2021