Computational approaches to selecting and optimising targets for structural biology

por Overton, Ian M., Barton, Geoffrey J.
Publicado 2011

Addressing Statistical Biases in Nucleotide-Derived Protein Databases for Proteogenomic Search Strategies

por Blakeley, Paul, Overton, Ian M., Hubbard, Simon J.
Publicado 2012

Transcriptome Profiling Reveals Enhanced Mitochondrial Activity as a Cold Adaptive Strategy to Hypothermia in Zebrafish Muscle

por Cahill, Thomas, Chan, Sherine, Overton, Ian M., Hardiman, Gary
Publicado 2023

Immune Cell Networks Uncover Candidate Biomarkers of Melanoma Immunotherapy Response

por Vo, Duong H. T., McGleave, Gerard, Overton, Ian M.
Publicado 2022

Validation of In Vitro Trained Transcriptomic Radiosensitivity Signatures in Clinical Cohorts

por O’Connor, John D., Overton, Ian M., McMahon, Stephen J.
Publicado 2023

XANNpred: Neural nets that predict the propensity of a protein to yield diffraction-quality crystals

por Overton, Ian M, van Niekerk, C A Johannes, Barton, Geoffrey J
Publicado 2011

RadSigBench: a framework for benchmarking functional genomics signatures of cancer cell radiosensitivity

por O’Connor, John D, Overton, Ian M, McMahon, Stephen J
Publicado 2022

TMA Navigator: network inference, patient stratification and survival analysis with tissue microarray data

por Lubbock, Alexander L. R., Katz, Elad, Harrison, David J., Overton, Ian M.
Publicado 2013

Strategies and techniques for quality control and semantic enrichment with multimodal data: a case study in colorectal cancer with eHDPrep

por Toner, Tom M, Pancholi, Rashi, Miller, Paul, Forster, Thorsten, Coleman, Helen G, Overton, Ian M
Publicado 2023

The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster

por Li, Xianghua, Overton, Ian M., Baines, Richard A., Keegan, Liam P., O’Connell, Mary A.
Publicado 2014

SynLeGG: analysis and visualization of multiomics data for discovery of cancer ‘Achilles Heels’ and gene function relationships

por Wappett, Mark, Harris, Adam, Lubbock, Alexander L R, Lobb, Ian, McDade, Simon, Overton, Ian M
Publicado 2021

PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate

por Wise, Helen M., Harris, Adam, Kriplani, Nisha, Schofield, Adam, Caldwell, Helen, Arends, Mark J., Overton, Ian M., Leslie, Nick R.
Publicado 2022

Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus

por Overton, Ian M, Graham, Shirley, Gould, Katherine A, Hinds, Jason, Botting, Catherine H, Shirran, Sally, Barton, Geoffrey J, Coote, Peter J
Publicado 2011

Functional Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling

por Overton, Ian M., Sims, Andrew H., Owen, Jeremy A., Heale, Bret S. E., Ford, Matthew J., Lubbock, Alexander L. R., Pairo-Castineira, Erola, Essafi, Abdelkader
Publicado 2020

Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer

por Lubbock, Alexander L. R., Stewart, Grant D., O’Mahony, Fiach C., Laird, Alexander, Mullen, Peter, O’Donnell, Marie, Powles, Thomas, Harrison, David J., Overton, Ian M.
Publicado 2017

TarO: a target optimisation system for structural biology

por Overton, Ian M., van Niekerk, C. A. Johannes, Carter, Lester G., Dawson, Alice, Martin, David M. A., Cameron, Scott, McMahon, Stephen A., White, Malcolm F., Hunter, William N., Naismith, James H., Barton, Geoffrey J.
Publicado 2008

Carbonic Anhydrase 9 Expression Increases with Vascular Endothelial Growth Factor–Targeted Therapy and Is Predictive of Outcome in Metastatic Clear Cell Renal Cancer

por Stewart, Grant D., O’Mahony, Fiach C., Laird, Alexander, Rashid, Sukaina, Martin, Sarah A., Eory, Lel, Lubbock, Alexander L.R., Nanda, Jyoti, O’Donnell, Marie, Mackay, Alan, Mullen, Peter, McNeill, S. Alan, Riddick, Antony C.P., Aitchison, Michael, Berney, Daniel, Bex, Axel, Overton, Ian M., Harrison, David J., Powles, Thomas
Publicado 2014

The Scottish Structural Proteomics Facility: targets, methods and outputs

por Oke, Muse, Carter, Lester G., Johnson, Kenneth A., Liu, Huanting, McMahon, Stephen A., Yan, Xuan, Kerou, Melina, Weikart, Nadine D., Kadi, Nadia, Sheikh, Md. Arif, Schmelz, Stefan, Dorward, Mark, Zawadzki, Michal, Cozens, Christopher, Falconer, Helen, Powers, Helen, Overton, Ian M., van Niekerk, C. A. Johannes, Peng, Xu, Patel, Prakash, Garrett, Roger A., Prangishvili, David, Botting, Catherine H., Coote, Peter J., Dryden, David T. F., Barton, Geoffrey J., Schwarz-Linek, Ulrich, Challis, Gregory L., Taylor, Garry L., White, Malcolm F., Naismith, James H.
Publicado 2010