Lysine Methyltransferase SETD7 (SET7/9) Regulates ROS Signaling through mitochondria and NFE2L2/ARE pathway

por He, Shuying, Owen, Dafydd R., Jelinsky, Scott A., Lin, Lih-Ling
Publicado 2015

Investigating 3,3-diaryloxetanes as potential bioisosteres through matched molecular pair analysis

por Dubois, Maryne A. J., Croft, Rosemary A., Ding, Yujie, Choi, Chulho, Owen, Dafydd R., Bull, James A., Mousseau, James J.
Publicado 2021

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit

por Fish, Paul V., Filippakopoulos, Panagis, Bish, Gerwyn, Brennan, Paul E., Bunnage, Mark E., Cook, Andrew S., Federov, Oleg, Gerstenberger, Brian S., Jones, Hannah, Knapp, Stefan, Marsden, Brian, Nocka, Karl, Owen, Dafydd R., Philpott, Martin, Picaud, Sarah, Primiano, Michael J., Ralph, Michael J., Sciammetta, Nunzio, Trzupek, John D.
Publicado 2012

Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance

por Fedorov, Oleg, Castex, Josefina, Tallant, Cynthia, Owen, Dafydd R., Martin, Sarah, Aldeghi, Matteo, Monteiro, Octovia, Filippakopoulos, Panagis, Picaud, Sarah, Trzupek, John D., Gerstenberger, Brian S., Bountra, Chas, Willmann, Dominica, Wells, Christopher, Philpott, Martin, Rogers, Catherine, Biggin, Philip C., Brennan, Paul E., Bunnage, Mark E., Schüle, Roland, Günther, Thomas, Knapp, Stefan, Müller, Susanne
Publicado 2015

Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation

por Meier, Julia C., Tallant, Cynthia, Fedorov, Oleg, Witwicka, Hanna, Hwang, Sung-Yong, van Stiphout, Ruud G., Lambert, Jean-Philippe, Rogers, Catherine, Yapp, Clarence, Gerstenberger, Brian S., Fedele, Vita, Savitsky, Pavel, Heidenreich, David, Daniels, Danette L., Owen, Dafydd R., Fish, Paul V., Igoe, Niall M., Bayle, Elliott D., Haendler, Bernard, Oppermann, Udo C.T., Buffa, Francesca, Brennan, Paul E., Müller, Susanne, Gingras, Anne Claude, Odgren, Paul R., Birnbaum, Mark J., Knapp, Stefan
Publicado 2017

Target 2035 – an update on private sector contributions

por Ackloo, Suzanne, Antolin, Albert A., Bartolome, Jose Manuel, Beck, Hartmut, Bullock, Alex, Betz, Ulrich A. K., Böttcher, Jark, Brown, Peter J., Chaturvedi, Menorca, Crisp, Alisa, Daniels, Danette, Dreher, Jan, Edfeldt, Kristina, Edwards, Aled M., Egner, Ursula, Elkins, Jon, Fischer, Christian, Glendorf, Tine, Goldberg, Steven, Hartung, Ingo V., Hillisch, Alexander, Homan, Evert, Knapp, Stefan, Köster, Markus, Krämer, Oliver, Llaveria, Josep, Lessel, Uta, Lindemann, Sven, Linderoth, Lars, Matsui, Hisanori, Michel, Maurice, Montel, Florian, Mueller-Fahrnow, Anke, Müller, Susanne, Owen, Dafydd R., Saikatendu, Kumar Singh, Santhakumar, Vijayaratnam, Sanderson, Wendy, Scholten, Cora, Schapira, Matthieu, Sharma, Sujata, Shireman, Brock, Sundström, Michael, Todd, Matthew H., Tredup, Claudia, Venable, Jennifer, Willson, Timothy M., Arrowsmith, Cheryl H.
Publicado 2023

Donated chemical probes for open science

por Müller, Susanne, Ackloo, Suzanne, Arrowsmith, Cheryl H, Bauser, Marcus, Baryza, Jeremy L, Blagg, Julian, Böttcher, Jark, Bountra, Chas, Brown, Peter J, Bunnage, Mark E, Carter, Adrian J, Damerell, David, Dötsch, Volker, Drewry, David H, Edwards, Aled M, Edwards, James, Elkins, Jon M, Fischer, Christian, Frye, Stephen V, Gollner, Andreas, Grimshaw, Charles E, IJzerman, Adriaan, Hanke, Thomas, Hartung, Ingo V, Hitchcock, Steve, Howe, Trevor, Hughes, Terry V, Laufer, Stefan, Li, Volkhart MJ, Liras, Spiros, Marsden, Brian D, Matsui, Hisanori, Mathias, John, O'Hagan, Ronan C, Owen, Dafydd R, Pande, Vineet, Rauh, Daniel, Rosenberg, Saul H, Roth, Bryan L, Schneider, Natalie S, Scholten, Cora, Singh Saikatendu, Kumar, Simeonov, Anton, Takizawa, Masayuki, Tse, Chris, Thompson, Paul R, Treiber, Daniel K, Viana, Amélia YI, Wells, Carrow I, Willson, Timothy M, Zuercher, William J, Knapp, Stefan, Mueller-Fahrnow, Anke
Publicado 2018

Target 2035 – update on the quest for a probe for every protein

por Müller, Susanne, Ackloo, Suzanne, Al Chawaf, Arij, Al-Lazikani, Bissan, Antolin, Albert, Baell, Jonathan B., Beck, Hartmut, Beedie, Shaunna, Betz, Ulrich A. K., Bezerra, Gustavo Arruda, Brennan, Paul E., Brown, David, Brown, Peter J., Bullock, Alex N., Carter, Adrian J., Chaikuad, Apirat, Chaineau, Mathilde, Ciulli, Alessio, Collins, Ian, Dreher, Jan, Drewry, David, Edfeldt, Kristina, Edwards, Aled M., Egner, Ursula, Frye, Stephen V., Fuchs, Stephen M., Hall, Matthew D., Hartung, Ingo V., Hillisch, Alexander, Hitchcock, Stephen H., Homan, Evert, Kannan, Natarajan, Kiefer, James R., Knapp, Stefan, Kostic, Milka, Kubicek, Stefan, Leach, Andrew R., Lindemann, Sven, Marsden, Brian D., Matsui, Hisanori, Meier, Jordan L., Merk, Daniel, Michel, Maurice, Morgan, Maxwell R., Mueller-Fahrnow, Anke, Owen, Dafydd R., Perry, Benjamin G., Rosenberg, Saul H., Saikatendu, Kumar Singh, Schapira, Matthieu, Scholten, Cora, Sharma, Sujata, Simeonov, Anton, Sundström, Michael, Superti-Furga, Giulio, Todd, Matthew H., Tredup, Claudia, Vedadi, Masoud, von Delft, Frank, Willson, Timothy M., Winter, Georg E., Workman, Paul, Arrowsmith, Cheryl H.
Publicado 2021