Genetics of Monogenic Diabetes: Present Clinical Challenges

por Misra, Shivani, Owen, Katharine R.
Publicado 2018

Response to Comment on: McDonald et al. High-Sensitivity CRP Discriminates HNF1A-MODY From Other Subtypes of Diabetes. Diabetes Care 2011;34:1860–1862

por McDonald, Tim J., Owen, Katharine R., Gloyn, Anna L., Hattersley, Andrew T.
Publicado 2011

High-Sensitivity CRP Discriminates HNF1A-MODY From Other Subtypes of Diabetes

por McDonald, Tim J., Shields, Beverley M., Lawry, Jane, Owen, Katharine R., Gloyn, Anna L., Ellard, Sian, Hattersley, Andrew T.
Publicado 2011

Assessment of High-Sensitivity C-Reactive Protein Levels as Diagnostic Discriminator of Maturity-Onset Diabetes of the Young Due to HNF1A Mutations

por Owen, Katharine R., Thanabalasingham, Gaya, James, Timothy J., Karpe, Fredrik, Farmer, Andrew J., McCarthy, Mark I., Gloyn, Anna L.
Publicado 2010

Low Frequency Variants in the Exons Only Encoding Isoform A of HNF1A Do Not Contribute to Susceptibility to Type 2 Diabetes

por Jafar-Mohammadi, Bahram, Groves, Christopher J., Owen, Katharine R., Frayling, Timothy M., Hattersley, Andrew T., McCarthy, Mark I., Gloyn, Anna L.
Publicado 2009

miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development

por Latreille, Mathieu, Herrmanns, Karolin, Renwick, Neil, Tuschl, Thomas, Malecki, Maciej T., McCarthy, Mark I., Owen, Katharine R., Rülicke, Thomas, Stoffel, Markus
Publicado 2015

Logistic regression has similar performance to optimised machine learning algorithms in a clinical setting: application to the discrimination between type 1 and type 2 diabetes in...

por Lynam, Anita L., Dennis, John M., Owen, Katharine R., Oram, Richard A., Jones, Angus G., Shields, Beverley M., Ferrat, Lauric A.
Publicado 2020

Metabolic Profiling in Maturity-Onset Diabetes of the Young (MODY) and Young Onset Type 2 Diabetes Fails to Detect Robust Urinary Biomarkers

por Gloyn, Anna L., Faber, Johan H., Malmodin, Daniel, Thanabalasingham, Gaya, Lam, Francis, Ueland, Per Magne, McCarthy, Mark I., Owen, Katharine R., Baunsgaard, Dorrit
Publicado 2012

Lixisenatide in type 1 diabetes: A randomised control trial of the effect of lixisenatide on post‐meal glucose excursions and glucagon in type 1 diabetes patients

por Ballav, Chitrabhanu, Dhere, Archana, Kennedy, Irene, Agbaje, Olorunsola F., White, Sarah, Franklin, Rachel, Hartmann, Bolette, Holst, Jens J., Holman, Rury R., Owen, Katharine R.
Publicado 2020

Reclassification of Diabetes Etiology in a Family With Multiple Diabetes Phenotypes

por Kavvoura, Fotini K., Raimondo, Anne, Thanabalasingham, Gayathiry, Barrett, Amy, Webster, Amanda L., Shears, Debbie, Mann, Nicholas P., Ellard, Sian, Gloyn, Anna L., Owen, Katharine R.
Publicado 2014

Systematic Assessment of Etiology in Adults With a Clinical Diagnosis of Young-Onset Type 2 Diabetes Is a Successful Strategy for Identifying Maturity-Onset Diabetes of the Young

por Thanabalasingham, Gaya, Pal, Aparna, Selwood, Mary P., Dudley, Christina, Fisher, Karen, Bingley, Polly J., Ellard, Sian, Farmer, Andrew J., McCarthy, Mark I., Owen, Katharine R.
Publicado 2012

Evaluation of Serum 1,5 Anhydroglucitol Levels as a Clinical Test to Differentiate Subtypes of Diabetes

por Pal, Aparna, Farmer, Andrew J., Dudley, Christina, Selwood, Mary P., Barrow, Beryl A., Klyne, Rhiannon, Grew, Jilly P., McCarthy, Mark I., Gloyn, Anna L., Owen, Katharine R.
Publicado 2010

Development of an exoglycosidase plate-based assay for detecting α1-3,4 fucosylation biomarker in individuals with HNF1A-MODY

por Demus, Daniel, Urbanowicz, Paulina A, Gardner, Richard A, Wu, Haiyang, Juszczak, Agata, Štambuk, Tamara, Medvidović, Edita Pape, Owen, Katharine R, Gornik, Olga, Juge, Nathalie, Spencer, Daniel I R
Publicado 2021

Combining Information from Common Type 2 Diabetes Risk Polymorphisms Improves Disease Prediction

por Weedon, Michael N, McCarthy, Mark I, Hitman, Graham, Walker, Mark, Groves, Christopher J, Zeggini, Eleftheria, Rayner, N. William, Shields, Beverley, Owen, Katharine R, Hattersley, Andrew T, Frayling, Timothy M
Publicado 2006

Cystatin C is not a good candidate biomarker for HNF1A-MODY

por Nowak, Natalia, Szopa, Magdalena, Thanabalasingham, Gaya, McDonald, Tim J., Colclough, Kevin, Skupien, Jan, James, Timothy J., Kiec-Wilk, Beata, Kozek, Elzbieta, Mlynarski, Wojciech, Hattersley, Andrew T., Owen, Katharine R., Malecki, Maciej T.
Publicado 2012

Maturity onset diabetes of the young due to HNF1A variants in Croatia

por Pavić, Tamara, Juszczak, Agata, Pape Medvidović, Edita, Burrows, Carla, Šekerija, Mario, Bennett, Amanda J, Ćuća Knežević, Jadranka, Gloyn, Anna L, Lauc, Gordan, McCarthy, Mark I, Gornik, Olga, Owen, Katharine R
Publicado 2018

Interlaboratory evaluation of plasma N-glycan antennary fucosylation as a clinical biomarker for HNF1A-MODY using liquid chromatography methods

por Demus, Daniel, Jansen, Bas C., Gardner, Richard A., Urbanowicz, Paulina A., Wu, Haiyang, Štambuk, Tamara, Juszczak, Agata, Medvidović, Edita Pape, Juge, Nathalie, Gornik, Olga, Owen, Katharine R., Spencer, Daniel I. R.
Publicado 2021

First-in-human, double-blind, randomized phase 1b study of peptide immunotherapy IMCY-0098 in new-onset type 1 diabetes

por Van Rampelbergh, Jean, Achenbach, Peter, Leslie, Richard David, Ali, Mohammad Alhadj, Dayan, Colin, Keymeulen, Bart, Owen, Katharine R., Kindermans, Martin, Parmentier, Frédéric, Carlier, Vincent, Ahangarani, Roxana R., Gebruers, Evelien, Bovy, Nicolas, Vanderelst, Luc, Van Mechelen, Marcelle, Vandepapelière, Pierre, Boitard, Christian
Publicado 2023

A Systematic Review of the use of Precision Diagnostics in Monogenic Diabetes

por Murphy, Rinki, Colclough, Kevin, Pollin, Toni I., Ikle, Jennifer M., Svalastoga, Pernille, Maloney, Kristin A., Saint-Martin, Cécile, Molnes, Janne, Misra, Shivani, Aukrust, Ingvild, de Franco, aiElisa, Flanagan, Sarah E., Njølstad, Pål R., Billings, Liana K., Owen, Katharine R, Gloyn, Anna L
Publicado 2023

The use of precision diagnostics for monogenic diabetes: a systematic review and expert opinion

por Murphy, Rinki, Colclough, Kevin, Pollin, Toni I., Ikle, Jennifer M., Svalastoga, Pernille, Maloney, Kristin A., Saint-Martin, Cécile, Molnes, Janne, Misra, Shivani, Aukrust, Ingvild, de Franco, Elisa, Flanagan, Sarah E., Njølstad, Pål R., Billings, Liana K., Owen, Katharine R., Gloyn, Anna L.
Publicado 2023