The bacterial toxin colibactin triggers prophage induction

por Silpe, Justin E., Wong, Joel W. H., Owen, Siân V., Baym, Michael, Balskus, Emily P.
Publicado 2022

A window into lysogeny: revealing temperate phage biology with transcriptomics

por Owen, Siân V., Canals, Rocío, Wenner, Nicolas, Hammarlöf, Disa L., Kröger, Carsten, Hinton, Jay C. D.
Publicado 2020

Direct characterization of the native structure and mechanics of cyanobacterial carboxysomes

por Faulkner, Matthew, Rodriguez-Ramos, Jorge, Dykes, Gregory F., Owen, Siân V., Casella, Selene, Simpson, Deborah M., Beynon, Robert J., Liu, Lu-Ning
Publicado 2017

RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium

por Srikumar, Shabarinath, Kröger, Carsten, Hébrard, Magali, Colgan, Aoife, Owen, Siân V., Sivasankaran, Sathesh K., Cameron, Andrew D. S., Hokamp, Karsten, Hinton, Jay C. D.
Publicado 2015

Characterization of the Prophage Repertoire of African Salmonella Typhimurium ST313 Reveals High Levels of Spontaneous Induction of Novel Phage BTP1

por Owen, Siân V., Wenner, Nicolas, Canals, Rocío, Makumi, Angela, Hammarlöf, Disa L., Gordon, Melita A., Aertsen, Abram, Feasey, Nicholas A., Hinton, Jay C. D.
Publicado 2017

The fitness landscape of the African Salmonella Typhimurium ST313 strain D23580 reveals unique properties of the pBT1 plasmid

por Canals, Rocío, Chaudhuri, Roy R., Steiner, Rebecca E., Owen, Siân V., Quinones-Olvera, Natalia, Gordon, Melita A., Baym, Michael, Ibba, Michael, Hinton, Jay C. D.
Publicado 2019

The use of chicken and insect infection models to assess the virulence of African Salmonella Typhimurium ST313

por Lacharme-Lora, Lizeth, Owen, Siân V., Blundell, Richard, Canals, Rocío, Wenner, Nicolas, Perez-Sepulveda, Blanca, Fong, Wai Yee, Gilroy, Rachel, Wigley, Paul, Hinton, Jay C. D.
Publicado 2019

Transcriptional Organization of the Salmonella Typhimurium Phage P22 pid ORFan Locus

por Wolput, Sanne, Makumi, Angela, Wicke, Laura, Bäcker, Leonard E., Cenens, William, Briers, Yves, Wenner, Nicolas A., Owen, Siân V., Hinton, Jay C. D., Lavigne, Rob, Aertsen, Abram
Publicado 2022

Genetic variation in the MacAB-TolC efflux pump influences pathogenesis of invasive Salmonella isolates from Africa

por Honeycutt, Jared D., Wenner, Nicolas, Li, Yan, Brewer, Susan M., Massis, Liliana M., Brubaker, Sky W., Chairatana, Phoom, Owen, Siân V., Canals, Rocío, Hinton, Jay C. D., Monack, Denise M.
Publicado 2020

Prophages encode phage-defense systems with cognate self-immunity

por Owen, Siân V., Wenner, Nicolas, Dulberger, Charles L., Rodwell, Ella V., Bowers-Barnard, Arthur, Quinones-Olvera, Natalia, Rigden, Daniel J., Rubin, Eric J., Garner, Ethan C., Baym, Michael, Hinton, Jay C.D.
Publicado 2021

Case-control investigation of invasive Salmonella disease in Malawi reveals no evidence of environmental or animal transmission of invasive strains, and supports human to human tra...

por Koolman, Leonard, Prakash, Reenesh, Diness, Yohane, Msefula, Chisomo, Nyirenda, Tonney S., Olgemoeller, Franziska, Wigley, Paul, Perez-Sepulveda, Blanca, Hinton, Jay C. D., Owen, Siân V., Feasey, Nicholas A., Ashton, Philip M., Gordon, Melita A.
Publicado 2022

Public health surveillance in the UK revolutionises our understanding of the invasive Salmonella Typhimurium epidemic in Africa

por Ashton, Philip M., Owen, Siân V., Kaindama, Lukeki, Rowe, Will P. M., Lane, Chris R., Larkin, Lesley, Nair, Satheesh, Jenkins, Claire, de Pinna, Elizabeth M., Feasey, Nicholas A., Hinton, Jay C. D., Dallman, Timothy J.
Publicado 2017

Diverse and abundant viruses exploit conjugative plasmids

por Quinones-Olvera, Natalia, Owen, Siân V., McCully, Lucy M., Marin, Maximillian G., Rand, Eleanor A., Fan, Alice C., Dosumu, Oluremi J. Martins, Paul, Kay, Castaño, Cleotilde E. Sanchez, Petherbridge, Rachel, Paull, Jillian S., Baym, Michael
Publicado 2023

Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella

por Hammarlöf, Disa L., Kröger, Carsten, Owen, Siân V., Canals, Rocío, Lacharme-Lora, Lizeth, Wenner, Nicolas, Schager, Anna E., Wells, Timothy J., Henderson, Ian R., Wigley, Paul, Hokamp, Karsten, Feasey, Nicholas A., Gordon, Melita A., Hinton, Jay C. D.
Publicado 2018

Mycobacterial nucleoid-associated protein Lsr2 is required for productive mycobacteriophage infection

por Dulberger, Charles L., Guerrero-Bustamante, Carlos A., Owen, Siân V., Wilson, Sean, Wuo, Michael G., Garlena, Rebecca A., Serpa, Lexi A., Russell, Daniel A., Zhu, Junhao, Braunecker, Ben J., Squyres, Georgia R., Baym, Michael, Kiessling, Laura L., Garner, Ethan C., Rubin, Eric J., Hatfull, Graham F.
Publicado 2023

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease

por Preciado-Llanes, Lorena, Aulicino, Anna, Canals, Rocío, Moynihan, Patrick J., Zhu, Xiaojun, Jambo, Ndaru, Nyirenda, Tonney S., Kadwala, Innocent, Sousa Gerós, Ana, Owen, Siân V., Jambo, Kondwani C., Kumwenda, Benjamin, Veerapen, Natacha, Besra, Gurdyal S., Gordon, Melita A., Hinton, Jay C. D., Napolitani, Giorgio, Salio, Mariolina, Simmons, Alison
Publicado 2020

Adding function to the genome of African Salmonella Typhimurium ST313 strain D23580

por Canals, Rocío, Hammarlöf, Disa L., Kröger, Carsten, Owen, Siân V., Fong, Wai Yee, Lacharme-Lora, Lizeth, Zhu, Xiaojun, Wenner, Nicolas, Carden, Sarah E., Honeycutt, Jared, Monack, Denise M., Kingsley, Robert A., Brownridge, Philip, Chaudhuri, Roy R., Rowe, Will P. M., Predeus, Alexander V., Hokamp, Karsten, Gordon, Melita A., Hinton, Jay C. D.
Publicado 2019

What’s in a Name? Species-Wide Whole-Genome Sequencing Resolves Invasive and Noninvasive Lineages of Salmonella enterica Serotype Paratyphi B

por Connor, Thomas R., Owen, Sian V., Langridge, Gemma, Connell, Steve, Nair, Satheesh, Reuter, Sandra, Dallman, Timothy J., Corander, Jukka, Tabing, Kristine C., Le Hello, Simon, Fookes, Maria, Doublet, Benoît, Zhou, Zhemin, Feltwell, Theresa, Ellington, Matthew J., Herrera, Silvia, Gilmour, Matthew, Cloeckaert, Axel, Achtman, Mark, Parkhill, Julian, Wain, John, De Pinna, Elizabeth, Weill, François-Xavier, Peters, Tansy, Thomson, Nick
Publicado 2016