PAPP‐A: a promising therapeutic target for healthy longevity

por Conover, Cheryl A., Oxvig, Claus
Publicado 2016

Pregnancy-Associated Plasma Protein-A2 and Anthropometry, Lifestyle, and Biochemical Factors in a Human Adult Population

por Steinbrecher, Astrid, Janke, Jürgen, Poy, Matthew N., Oxvig, Claus, Pischon, Tobias
Publicado 2017

A common variant of the pregnancy-associated plasma protein-A (PAPPA) gene encodes a protein with reduced proteolytic activity towards IGF-binding proteins

por Bøtkjær, Jane Alrø, Noer, Pernille Rimmer, Oxvig, Claus, Yding Andersen, Claus
Publicado 2019

Author Correction: A common variant of the pregnancy-associated plasma protein-A (PAPPA) gene encodes a protein with reduced proteolytic activity towards IGF-binding proteins

por Bøtkjær, J. A., Noer, P. R., Oxvig, Claus, Andersen, Claus Yding
Publicado 2019

One level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiology

por Argente, Jesús, Chowen, Julie A, Pérez‐Jurado, Luis A, Frystyk, Jan, Oxvig, Claus
Publicado 2017

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity

por Mikkelsen, Jakob H., Resch, Zachary T., Kalra, Bhanu, Savjani, Gopal, Kumar, Ajay, Conover, Cheryl A., Oxvig, Claus
Publicado 2014

Insulin‐Like Growth Factor Binding Protein 4 Fragments Provide Incremental Prognostic Information on Cardiovascular Events in Patients With ST‐Segment Elevation Myocardial Infarcti...

por Hjortebjerg, Rikke, Lindberg, Søren, Pedersen, Sune, Mogelvang, Rasmus, Jensen, Jan S., Oxvig, Claus, Frystyk, Jan, Bjerre, Mette
Publicado 2017

Prognostic relevance and performance characteristics of serum IGFBP‐2 and PAPP‐A in women with breast cancer: a long‐term Danish cohort study

por Espelund, Ulrick, Renehan, Andrew G., Cold, Søren, Oxvig, Claus, Lancashire, Lee, Su, Zhenqiang, Flyvbjerg, Allan, Frystyk, Jan
Publicado 2018

Duplication and Diversification of the Hypoxia-Inducible IGFBP-1 Gene in Zebrafish

por Kamei, Hiroyasu, Lu, Ling, Jiao, Shuang, Li, Yun, Gyrup, Claus, Laursen, Lisbeth S., Oxvig, Claus, Zhou, Jianfeng, Duan, Cunming
Publicado 2008

Porcine synapsin 1: SYN1 gene analysis and functional characterization of the promoter()()

por Hedegaard, Claus, Kjaer-Sorensen, Kasper, Madsen, Lone Bruhn, Henriksen, Carina, Momeni, Jamal, Bendixen, Christian, Oxvig, Claus, Larsen, Knud
Publicado 2013

OR07-5 A Cross-Sectional Study of IGF-I Bioavailability through Childhood: Associations with PAPP-A2 and Anthropometric Data

por Fujimoto, Masanobu, Khoury, Jane, Khoury, Philip, Kalra, Bhanu, Kumar, Ajay, Sluss, Patrick, Oxvig, Claus, Hwa, Vivian, Dauber, Andrew
Publicado 2019

Pregnancy-Associated Plasma Protein-A2 Is Associated With Mortality in Patients With Lung Cancer

por Hjortebjerg, Rikke, Espelund, Ulrick, Rasmussen, Torben Riis, Folkersen, Birgitte, Steiniche, Torben, Georgsen, Jeanette Bæhr, Oxvig, Claus, Frystyk, Jan
Publicado 2020

A characteristic signature of insulin-like growth factor (IGF) axis expression during osteogenic differentiation of human dental pulp cells (hDPCs): Potential co-ordinated regulati...

por Al-Khafaji, Hasanain, Noer, Pernille R., Alkharobi, Hanna, Alhodhodi, Aishah, Meade, Josephine, El-Gendy, Reem, Oxvig, Claus, Beattie, James
Publicado 2018

Insulin- like Growth Factor-Binding Protein Action in Bone Tissue: A Key Role for Pregnancy- Associated Plasma Protein-A

por Beattie, James, Al-Khafaji, Hasanain, Noer, Pernille R., Alkharobi, Hanaa Esa, Alhodhodi, Aishah, Meade, Josephine, El-Gendy, Reem, Oxvig, Claus
Publicado 2018

Corrigendum: Insulin- like Growth Factor-Binding Protein Action in Bone Tissue: A Key Role for Pregnancy- Associated Plasma Protein-A

por Beattie, James, Al-Khafaji, Hasanain, Noer, Pernille R., Alkharobi, Hanaa Esa, Alhodhodi, Aishah, Meade, Josephine, El-Gendy, Reem, Oxvig, Claus
Publicado 2018

Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism

por Kobberø, Sara Dam, Gajhede, Michael, Mirza, Osman Asghar, Kløverpris, Søren, Kjær, Troels Rønn, Mikkelsen, Jakob Hauge, Boesen, Thomas, Oxvig, Claus
Publicado 2022

Molecular Cloning and Characterization of Porcine Na(+)/K(+)-ATPase Isoforms α1, α2, α3 and the ATP1A3 Promoter

por Henriksen, Carina, Kjaer-Sorensen, Kasper, Einholm, Anja Pernille, Madsen, Lone Bruhn, Momeni, Jamal, Bendixen, Christian, Oxvig, Claus, Vilsen, Bente, Larsen, Knud
Publicado 2013

Identification of Transglutaminase Reactive Residues in Human Osteopontin and Their Role in Polymerization

por Christensen, Brian, Zachariae, Elias D., Scavenius, Carsten, Thybo, Morten, Callesen, Morten M., Kløverpris, Søren, Oxvig, Claus, Enghild, Jan J., Sørensen, Esben S.
Publicado 2014

The metalloproteinase Papp-aa controls epithelial cell quiescence-proliferation transition

por Liu, Chengdong, Li, Shuang, Noer, Pernille Rimmer, Kjaer-Sorensen, Kasper, Juhl, Anna Karina, Goldstein, Allison, Ke, Caihuan, Oxvig, Claus, Duan, Cunming
Publicado 2020

Lactation opposes pappalysin‐1‐driven pregnancy‐associated breast cancer

por Takabatake, Yukie, Oxvig, Claus, Nagi, Chandandeep, Adelson, Kerin, Jaffer, Shabnam, Schmidt, Hank, Keely, Patricia J, Eliceiri, Kevin W, Mandeli, John, Germain, Doris
Publicado 2016