Phosphorylation states of cell cycle and DNA repair proteins can be altered by the nsSNPs

por Savas, Sevtap, Ozcelik, Hilmi
Publicado 2005

Human SNPs resulting in premature stop codons and protein truncation

por Savas, Sevtap, Tuzmen, Sukru, Ozcelik, Hilmi
Publicado 2006

Missense Variants of Uncertain Significance (VUS) Altering the Phosphorylation Patterns of BRCA1 and BRCA2

por Tram, Eric, Savas, Sevtap, Ozcelik, Hilmi
Publicado 2013

Functional nsSNPs from carcinogenesis-related genes expressed in breast tissue: Potential breast cancer risk alleles and their distribution across human populations

por Savas, Sevtap, Schmidt, Steffen, Jarjanazi, Hamdi, Ozcelik, Hilmi
Publicado 2006

Genome Wide Screening of CAG Trinucleotide Repeat Lengths in Breast Cancer

por Jarjanazi, Hamdi, Li, Hong, Andrulis, Irene L., Ozcelik, Hilmi
Publicado 2006

Menopausal Status Modifies Breast Cancer Risk Associated with the Myeloperoxidase (MPO) G463A Polymorphism in Caucasian Women: A Meta-Analysis

por Pabalan, Noel, Jarjanazi, Hamdi, Sung, Lillian, Li, Hong, Ozcelik, Hilmi
Publicado 2012

Methodological issues in detecting gene-gene interactions in breast cancer susceptibility: a population-based study in Ontario

por Briollais, Laurent, Wang, Yuanyuan, Rajendram, Isaac, Onay, Venus, Shi, Ellen, Knight, Julia, Ozcelik, Hilmi
Publicado 2007

Identification of germline alterations of the mad homology 2 domain of SMAD3 and SMAD4 from the Ontario site of the breast cancer family registry (CFR)

por Tram, Eric, Ibrahim-zada, Irada, Briollais, Laurent, Knight, Julia A, Andrulis, Irene L, Ozcelik, Hilmi
Publicado 2011

Bioinformatic analyses identifies novel protein-coding pharmacogenomic markers associated with paclitaxel sensitivity in NCI60 cancer cell lines

por Eng, Lawson, Ibrahim-zada, Irada, Jarjanazi, Hamdi, Savas, Sevtap, Meschian, Mehran, Pritchard, Kathleen I, Ozcelik, Hilmi
Publicado 2011

A Whole-Genome SNP Association Study of NCI60 Cell Line Panel Indicates a Role of Ca(2+) Signaling in Selenium Resistance

por Savas, Sevtap, Briollais, Laurent, Ibrahim-zada, Irada, Jarjanazi, Hamdi, Choi, Yun Hee, Musquera, Mireia, Fleshner, Neil, Venkateswaran, Vasundara, Ozcelik, Hilmi
Publicado 2010

Discovery, Validation and Characterization of Erbb4 and Nrg1 Haplotypes Using Data from Three Genome-Wide Association Studies of Schizophrenia

por Agim, Zeynep Sena, Esendal, Melda, Briollais, Laurent, Uyan, Ozgun, Meschian, Mehran, Martinez, Luis Antonio Mendoza, Ding, Yongmei, Basak, A. Nazli, Ozcelik, Hilmi
Publicado 2013

SNP-SNP interactions in breast cancer susceptibility

por Onay, Venüs Ümmiye, Briollais, Laurent, Knight, Julia A, Shi, Ellen, Wang, Yuanyuan, Wells, Sean, Li, Hong, Rajendram, Isaac, Andrulis, Irene L, Ozcelik, Hilmi
Publicado 2006

Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk

por Onay, Ummiye V, Aaltonen, Kirsimari, Briollais, Laurent, Knight, Julia A, Pabalan, Noel, Kilpivaara, Outi, Andrulis, Irene L, Blomqvist, Carl, Nevanlinna, Heli, Ozcelik, Hilmi
Publicado 2008

Discovery of Novel Hypermethylated Genes in Prostate Cancer Using Genomic CpG Island Microarrays

por Kron, Ken, Pethe, Vaijayanti, Briollais, Laurent, Sadikovic, Bekim, Ozcelik, Hilmi, Sunderji, Alia, Venkateswaran, Vasundara, Pinthus, Jehonathan, Fleshner, Neil, van der Kwast, Theodorus, Bapat, Bharati
Publicado 2009

ATXN2 and Its Neighbouring Gene SH2B3 Are Associated with Increased ALS Risk in the Turkish Population

por Lahut, Suna, Ömür, Özgür, Uyan, Özgün, Ağım, Zeynep Sena, Özoğuz, Aslihan, Parman, Yeşim, Deymeer, Feza, Oflazer, Piraye, Koç, Filiz, Özçelik, Hilmi, Auburger, Georg, Başak, A. Nazlı
Publicado 2012

Genome-Wide Copy Number Variation in Sporadic Amyotrophic Lateral Sclerosis in the Turkish Population: Deletion of EPHA3 Is a Possible Protective Factor

por Uyan, Özgün, Ömür, Özgür, Ağım, Zeynep Sena, Özoğuz, Aslıhan, Li, Hong, Parman, Yeşim, Deymeer, Feza, Oflazer, Piraye, Koç, Filiz, Tan, Ersin, Özçelik, Hilmi, Başak, A. Nazlı
Publicado 2013

Polymorphisms cMyc-N11S and p27-V109G and breast cancer risk and prognosis

por Figueiredo, Jane C, Knight, Julia A, Cho, Stewart, Savas, Sevtap, Onay, U Venus, Briollais, Laurent, Goodwin, Pamela J, McLaughlin, John R, Andrulis, Irene L, Ozcelik, Hilmi
Publicado 2007

NCI60 Cancer Cell Line Panel Data and RNAi Analysis Help Identify EAF2 as a Modulator of Simvastatin and Lovastatin Response in HCT-116 Cells

por Savas, Sevtap, Azorsa, David O., Jarjanazi, Hamdi, Ibrahim-Zada, Irada, Gonzales, Irma M., Arora, Shilpi, Henderson, Meredith C., Choi, Yun Hee, Briollais, Laurent, Ozcelik, Hilmi, Tuzmen, Sukru
Publicado 2011

Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family Registry

por Smith, Letitia D, Tesoriero, Andrea A, Wong, Ee M, Ramus, Susan J, O'Malley, Frances P, Mulligan, Anna Marie, Terry, Mary Beth, Senie, Ruby T, Santella, Regina M, John, Esther M, Andrulis, Irene L, Ozcelik, Hilmi, Daly, Mary B, Godwin, Andrew K, Buys, Saundra S, Fox, Stephen, Goldgar, David E, Giles, Graham G, Hopper, John L, Southey, Melissa C
Publicado 2011

Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

por Gaudet, Mia M., Kirchhoff, Tomas, Green, Todd, Vijai, Joseph, Korn, Joshua M., Guiducci, Candace, Segrè, Ayellet V., McGee, Kate, McGuffog, Lesley, Kartsonaki, Christiana, Morrison, Jonathan, Healey, Sue, Sinilnikova, Olga M., Stoppa-Lyonnet, Dominique, Mazoyer, Sylvie, Gauthier-Villars, Marion, Sobol, Hagay, Longy, Michel, Frenay, Marc, GEMO Study Collaborators, Hogervorst, Frans B. L., Rookus, Matti A., Collée, J. Margriet, Hoogerbrugge, Nicoline, van Roozendaal, Kees E. P., Piedmonte, Marion, Rubinstein, Wendy, Nerenstone, Stacy, Van Le, Linda, Blank, Stephanie V., Caldés, Trinidad, de la Hoya, Miguel, Nevanlinna, Heli, Aittomäki, Kristiina, Lazaro, Conxi, Blanco, Ignacio, Arason, Adalgeir, Johannsson, Oskar T., Barkardottir, Rosa B., Devilee, Peter, Olopade, Olofunmilayo I., Neuhausen, Susan L., Wang, Xianshu, Fredericksen, Zachary S., Peterlongo, Paolo, Manoukian, Siranoush, Barile, Monica, Viel, Alessandra, Radice, Paolo, Phelan, Catherine M., Narod, Steven, Rennert, Gad, Lejbkowicz, Flavio, Flugelman, Anath, Andrulis, Irene L., Glendon, Gord, Ozcelik, Hilmi, Toland, Amanda E., Montagna, Marco, D'Andrea, Emma, Friedman, Eitan, Laitman, Yael, Borg, Ake, Beattie, Mary, Ramus, Susan J., Domchek, Susan M., Nathanson, Katherine L., Rebbeck, Tim, Spurdle, Amanda B., Chen, Xiaoqing, Holland, Helene, John, Esther M., Hopper, John L., Buys, Saundra S., Daly, Mary B., Southey, Melissa C., Terry, Mary Beth, Tung, Nadine, Overeem Hansen, Thomas V., Nielsen, Finn C., Greene, Mark I., Mai, Phuong L., Osorio, Ana, Durán, Mercedes, Andres, Raquel, Benítez, Javier, Weitzel, Jeffrey N., Garber, Judy, Hamann, Ute, Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, Platte, Radka, Evans, D. Gareth, Lalloo, Fiona, Eeles, Ros, Izatt, Louise, Walker, Lisa, Eason, Jacqueline, Barwell, Julian, Godwin, Andrew K., Schmutzler, Rita K., Wappenschmidt, Barbara, Engert, Stefanie, Arnold, Norbert, Gadzicki, Dorothea, Dean, Michael, Gold, Bert, Klein, Robert J., Couch, Fergus J., Chenevix-Trench, Georgia, Easton, Douglas F., Daly, Mark J., Antoniou, Antonis C., Altshuler, David M., Offit, Kenneth
Publicado 2010