Blocking estrogen-induced AMH expression is crucial for normal follicle formation

por Tanimoto, Ren, Sekii, Kiyono, Morohaku, Kanako, Li, Jianzhen, Pépin, David, Obata, Yayoi
Publicado 2021

Mutational Analysis of the Putative Anti-Müllerian Hormone (AMH) Binding Interface on its Type II Receptor, AMHR2

por Hart, Kaitlin N, Pépin, David, Czepnik, Magdalena, Donahoe, Patricia K, Thompson, Thomas B
Publicado 2020

A genome-wide strategy to identify causes and consequences of retrotransposon expression finds activation by BRCA1 in ovarian cancer

por Alkailani, Maisa, Palidwor, Gareth, Poulin, Ariane, Mohan, Raghav, Pepin, David, Vanderhyden, Barbara, Gibbings, Derrick
Publicado 2021

Towards international standardization of immunoassays for Müllerian inhibiting substance/anti-Müllerian hormone

por Ferguson, Jackie MC, Pépin, David, Duru, Chinwe, Matejtschuk, Paul, Donahoe, Patricia K, Burns, Chris J
Publicado 2018

Kallikreins 5, 6 and 10 Differentially Alter Pathophysiology and Overall Survival in an Ovarian Cancer Xenograft Model

por Pépin, David, Shao, Zhong-Qi, Huppé, Geneviève, Wakefield, Andrea, Chu, Chee-Wui, Sharif, Zahra, Vanderhyden, Barbara C.
Publicado 2011

A role for orphan nuclear receptor liver receptor homolog-1 (LRH-1, NR5A2) in primordial follicle activation

por Meinsohn, Marie-Charlotte, Hughes, Camilla H. K., Estienne, Anthony, Saatcioglu, Hatice D., Pépin, David, Duggavathi, Raj, Murphy, Bruce D.
Publicado 2021

Single-cell immunophenotyping of the fetal immune response to maternal SARS-CoV-2 infection in late gestation

por Matute, Juan, Finander, Benjamin, Pepin, David, Ai, Xinbin, Smith, Neal, Li, Jonathan, Edlow, Andrea, Villani, Alexandra, Lerou, Paul, Kalish, Brian
Publicado 2021

Neoadjuvant Treatment With Müllerian-Inhibiting Substance Synchronizes Follicles and Enhances Superovulation Yield

por Kano, Motohiro, Hsu, Jennifer Y, Saatcioglu, Hatice D, Nagykery, Nicholas, Zhang, LiHua, Morris Sabatini, Mary E, Donahoe, Patricia K, Pépin, David
Publicado 2019

Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-β family

por Hart, Kaitlin N., Stocker, William A., Nagykery, Nicholas G., Walton, Kelly L., Harrison, Craig A., Donahoe, Patricia K., Pépin, David, Thompson, Thomas B.
Publicado 2021

Urinary phthalate metabolite concentrations are negatively associated with follicular fluid anti-müllerian hormone concentrations in women undergoing fertility treatment

por Sacha, Caitlin R., Souter, Irene, Williams, Paige L., Chavarro, Jorge E., Ford, Jennifer, Mahalingaiah, Shruthi, Donahoe, Patricia K., Hauser, Russ, Pépin, David, Mínguez-Alarcón, Lidia
Publicado 2021

Single-cell immunophenotyping of the fetal immune response to maternal SARS-CoV-2 infection in late gestation

por Matute, Juan D., Finander, Benjamin, Pepin, David, Ai, Xingbin, Smith, Neal P., Li, Jonathan Z., Edlow, Andrea G., Villani, Alexandra-Chloe, Lerou, Paul H., Kalish, Brian T.
Publicado 2021

CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis

por Sosulski, Amanda, Horn, Heiko, Zhang, Lihua, Coletti, Caroline, Vathipadiekal, Vinod, Castro, Cesar M., Birrer, Michael J., Nagano, Osamu, Saya, Hideyuki, Lage, Kasper, Donahoe, Patricia K., Pépin, David
Publicado 2016

A screen of repurposed drugs identifies AMHR2/MISR2 agonists as potential contraceptives

por Li, Yi, Wei, Lina, Meinsohn, Marie-Charlotte, Suliman, Rana, Chauvin, Maeva, Berstler, Jim, Hartland, Kate, Jensen, Mark M., Sicher, Natalie A., Nagykery, Nicholas, Donahoe, Patricia K., Pepin, David
Publicado 2022

Anti-Müllerian hormone (AMH) autocrine signaling promotes survival and proliferation of ovarian cancer cells

por Chauvin, Maëva, Garambois, Véronique, Colombo, Pierre-Emmanuel, Chentouf, Myriam, Gros, Laurent, Brouillet, Jean-Paul, Robert, Bruno, Jarlier, Marta, Dumas, Karen, Martineau, Pierre, Navarro-Teulon, Isabelle, Pépin, David, Chardès, Thierry, Pèlegrin, André
Publicado 2021

PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation

por Sabbatino, Francesco, Wang, Yangyang, Wang, Xinhui, Flaherty, Keith T., Yu, Ling, Pepin, David, Scognamiglio, Giosue', Pepe, Stefano, Kirkwood, John M., Cooper, Zachary A., Frederick, Dennie T., Wargo, Jennifer A., Ferrone, Soldano, Ferrone, Cristina R.
Publicado 2014

Chronic superphysiologic AMH promotes premature luteinization of antral follicles in human ovarian xenografts

por Man, Limor, Lustgarten Guahmich, Nicole, Kallinos, Eleni, Caiazza, Barbara, Khan, Monica, Liu, Zong-Ying, Patel, Ritaben, Torres, Carmen, Pepin, David, Yang, He S., Bodine, Richard, Zaninovic, Nikica, Schattman, Glenn, Rosenwaks, Zev, James, Daylon
Publicado 2022

A single-cell atlas of the cycling murine ovary

por Morris, Mary E, Meinsohn, Marie-Charlotte, Chauvin, Maeva, Saatcioglu, Hatice D, Kashiwagi, Aki, Sicher, Natalie A, Nguyen, Ngoc, Yuan, Selena, Stavely, Rhian, Hyun, Minsuk, Donahoe, Patricia K, Sabatini, Bernardo L, Pépin, David
Publicado 2022

Anti-Müllerian hormone concentration regulates activin receptor-like kinase-2/3 expression levels with opposing effects on ovarian cancer cell survival

por Chauvin, Maëva, Garambois, Véronique, Choblet, Sylvie, Colombo, Pierre-Emmanuel, Chentouf, Myriam, Gros, Laurent, De Brauwere, David-Paul, Duonor-Cerutti, Martine, Dumas, Karen, Robert, Bruno, Jarlier, Marta, Martineau, Pierre, Navarro-Teulon, Isabelle, Pépin, David, Chardès, Thierry, Pèlegrin, André
Publicado 2021

Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer

por Qi, Ruogu, Wang, Yongheng, Bruno, Peter M., Xiao, Haihua, Yu, Yingjie, Li, Ting, Lauffer, Sam, Wei, Wei, Chen, Qixian, Kang, Xiang, Song, Haiqin, Yang, Xi, Huang, Xing, Detappe, Alexandre, Matulonis, Ursula, Pepin, David, Hemann, Michael T., Birrer, Michael J., Ghoroghchian, P. Peter
Publicado 2017

Publisher Correction: Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer

por Qi, Ruogu, Wang, Yongheng, Bruno, Peter M., Xiao, Haihua, Yu, Yingjie, Li, Ting, Lauffer, Sam, Wei, Wei, Chen, Qixian, Kang, Xiang, Song, Haiqin, Yang, Xi, Huang, Xing, Detappe, Alexandre, Matulonis, Ursula, Pepin, David, Hemann, Michael T., Birrer, Michael J., Ghoroghchian, P. Peter
Publicado 2018