Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion

por Lakomek, Nils-Alexander, Yavuz, Halenur, Jahn, Reinhard, Pérez-Lara, Ángel
Publicado 2019

Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding

por Scacioc, Andreea, Schmidt, Carla, Hofmann, Tommy, Urlaub, Henning, Kühnel, Karin, Pérez-Lara, Ángel
Publicado 2017

Phosphatidylinositol 4,5-Bisphosphate Decreases the Concentration of Ca(2+), Phosphatidylserine and Diacylglycerol Required for Protein Kinase C α to Reach Maximum Activity

por Egea-Jiménez, Antonio L., Pérez-Lara, Ángel, Corbalán-García, Senena, Gómez-Fernández, Juan C.
Publicado 2013

Control of membrane gaps by synaptotagmin-Ca(2+) measured with a novel membrane distance ruler

por Lin, Chao-Chen, Seikowski, Jan, Pérez-Lara, Angel, Jahn, Reinhard, Höbartner, Claudia, Walla, Peter Jomo
Publicado 2014

Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes

por Wittig, Sabine, Ganzella, Marcelo, Barth, Marie, Kostmann, Susann, Riedel, Dietmar, Pérez-Lara, Ángel, Jahn, Reinhard, Schmidt, Carla
Publicado 2021

Phosphatidylinositol-4,5-Bisphosphate Enhances Anionic Lipid Demixing by the C2 Domain of PKCα

por Egea-Jiménez, Antonio L., Fernández-Martínez, Ana M., Pérez-Lara, Ángel, de Godos, Ana, Corbalán-García, Senena, Gómez-Fernández, Juan C.
Publicado 2014

PtdInsP(2) and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium

por Pérez-Lara, Ángel, Thapa, Anusa, Nyenhuis, Sarah B, Nyenhuis, David A, Halder, Partho, Tietzel, Michael, Tittmann, Kai, Cafiso, David S, Jahn, Reinhard
Publicado 2016

Synaptotagmin-1 binds to PIP(2)-containing membrane but not to SNAREs at physiological ionic strength

por Park, Yongsoo, Seo, Jong Bae, Fraind, Alicia, Pérez-Lara, Angel, Yavuz, Halenur, Han, Kyungreem, Jung, Seung-Ryoung, Kattan, Iman, Walla, Peter Jomo, Choi, MooYoung, Cafiso, David S., Koh, Duk-Su, Jahn, Reinhard
Publicado 2015

Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex

por Oroz, Javier, Chang, Bliss J., Wysoczanski, Piotr, Lee, Chung-Tien, Pérez-Lara, Ángel, Chakraborty, Pijush, Hofele, Romina V., Baker, Jeremy D., Blair, Laura J., Biernat, Jacek, Urlaub, Henning, Mandelkow, Eckhard, Dickey, Chad A., Zweckstetter, Markus
Publicado 2018

Modulation of K(V)4.3-KChIP2 Channels by IQM-266: Role of DPP6 and KCNE2

por de Benito-Bueno, Angela, Socuellamos, Paula G., Merinero, Yaiza G., Cercos, Pilar, Izquierdo, Carolina, Daniel-Mozo, Miguel, Marín-Olivero, Irene, Perez-Lara, Angel, Gonzalez-Vera, Juan A., Orte, Angel, Albert, Armando, Martin-Martinez, Mercedes, Gutierrez-Rodriguez, Marta, Valenzuela, Carmen
Publicado 2022

Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease

por Lüningschrör, Patrick, Binotti, Beyenech, Dombert, Benjamin, Heimann, Peter, Perez-Lara, Angel, Slotta, Carsten, Thau-Habermann, Nadine, R. von Collenberg, Cora, Karl, Franziska, Damme, Markus, Horowitz, Arie, Maystadt, Isabelle, Füchtbauer, Annette, Füchtbauer, Ernst-Martin, Jablonka, Sibylle, Blum, Robert, Üçeyler, Nurcan, Petri, Susanne, Kaltschmidt, Barbara, Jahn, Reinhard, Kaltschmidt, Christian, Sendtner, Michael
Publicado 2017