A Novel Scaffold-Based Hybrid Multicellular Model for Pancreatic Ductal Adenocarcinoma—Toward a Better Mimicry of the in vivo Tumor Microenvironment

por Gupta, Priyanka, Pérez-Mancera, Pedro A., Kocher, Hemant, Nisbet, Andrew, Schettino, Giuseppe, Velliou, Eirini G.
Publicado 2020

The role of microRNAs in the modulation of cancer-associated fibroblasts activity during pancreatic cancer pathogenesis

por Barrera, Lawrence N., Ridley, P. Matthew, Bermejo-Rodriguez, Camino, Costello, Eithne, Perez-Mancera, Pedro A.
Publicado 2022

FUS-DDIT3 Prevents the Development of Adipocytic Precursors in Liposarcoma by Repressing PPARγ and C/EBPα and Activating eIF4E

por Pérez-Mancera, Pedro A., Bermejo-Rodríguez, Camino, Sánchez-Martín, Manuel, Abollo-Jiménez, Fernando, Pintado, Belén, Sánchez-García, Isidro
Publicado 2008

Chemoradiotherapy screening in a novel biomimetic polymer based pancreatic cancer model

por Gupta, Priyanka, Totti, Stella, Pérez-Mancera, Pedro A., Dyke, Eleanor, Nisbet, Andrew, Schettino, Giuseppe, Webb, Roger, Velliou, Eirini G.
Publicado 2019

Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence

por Sadaie, Mahito, Salama, Rafik, Carroll, Thomas, Tomimatsu, Kosuke, Chandra, Tamir, Young, Andrew R.J., Narita, Masako, Pérez-Mancera, Pedro A., Bennett, Dorothy C., Chong, Heung, Kimura, Hiroshi, Narita, Masashi
Publicado 2013

STAG2 is a clinically relevant tumor suppressor in pancreatic ductal adenocarcinoma

por Evers, Lisa, Perez-Mancera, Pedro A, Lenkiewicz, Elizabeth, Tang, Nanyun, Aust, Daniela, Knösel, Thomas, Rümmele, Petra, Holley, Tara, Kassner, Michelle, Aziz, Meraj, Ramanathan, Ramesh K, Von Hoff, Daniel D, Yin, Holly, Pilarsky, Christian, Barrett, Michael T
Publicado 2014

Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53

por Kirschner, Kristina, Samarajiwa, Shamith A., Cairns, Jonathan M., Menon, Suraj, Pérez-Mancera, Pedro A., Tomimatsu, Kosuke, Bermejo-Rodriguez, Camino, Ito, Yoko, Chandra, Tamir, Narita, Masako, Lyons, Scott K., Lynch, Andy G., Kimura, Hiroshi, Ohbayashi, Tetsuya, Tavaré, Simon, Narita, Masashi
Publicado 2015

A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo

por Cassidy, Liam D., Young, Andrew RJ., Pérez-Mancera, Pedro A., Nimmervoll, Birgit, Jaulim, Adil, Chen, Hung-Chang, McIntyre, Dominick J. O., Brais, Rebecca, Ricketts, Thomas, Pacey, Simon, De La Roche, Maike, Gilbertson, Richard J., Rubinsztein, David C., Narita, Masashi
Publicado 2018

Kras(P34R) and Kras(T58I) mutations induce distinct RASopathy phenotypes in mice

por Wong, Jasmine C., Perez-Mancera, Pedro A., Huang, Tannie Q., Kim, Jangkyung, Grego-Bessa, Joaquim, del pilar Alzamora, Maria, Kogan, Scott C., Sharir, Amnon, Keefe, Susan H., Morales, Carolina E., Schanze, Denny, Castel, Pau, Hirose, Kentaro, Huang, Guo N., Zenker, Martin, Sheppard, Dean, Klein, Ophir D., Tuveson, David A., Braun, Benjamin S., Shannon, Kevin
Publicado 2020

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium

por Holland, Daniel G, Burleigh, Angela, Git, Anna, Goldgraben, Mae A, Perez-Mancera, Pedro A, Chin, Suet-Feung, Hurtado, Antonio, Bruna, Alejandra, Ali, H Raza, Greenwood, Wendy, Dunning, Mark J, Samarajiwa, Shamith, Menon, Suraj, Rueda, Oscar M, Lynch, Andy G, McKinney, Steven, Ellis, Ian O, Eaves, Connie J, Carroll, Jason S, Curtis, Christina, Aparicio, Samuel, Caldas, Carlos
Publicado 2011

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

por Pérez-Mancera, Pedro A., Rust, Alistair G., van der Weyden, Louise, Kristiansen, Glen, Li, Allen, Sarver, Aaron L., Silverstein, Kevin A. T., Grützmann, Robert, Aust, Daniela, Rümmele, Petra, Knösel, Thomas, Herd, Colin, Stemple, Derek L., Kettleborough, Ross, Brosnan, Jacqueline A., Li, Ang, Morgan, Richard, Knight, Spencer, Yu, Jun, Stegeman, Shane, Collier, Lara S., ten Hoeve, Jelle J., de Ridder, Jeroen, Klein, Alison P., Goggins, Michael, Hruban, Ralph H., Chang, David K., Biankin, Andrew V., Grimmond, Sean M., Wessels, Lodewyk F. A., Wood, Stephen A., Iacobuzio-Donahue, Christine A., Pilarsky, Christian, Largaespada, David A., Adams, David J., Tuveson, David A.
Publicado 2012

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

por Varela, Ignacio, Tarpey, Patrick, Raine, Keiran, Huang, Dachuan, Ong, Choon Kiat, Stephens, Philip, Davies, Helen, Jones, David, Lin, Meng-Lay, Teague, Jon, Bignell, Graham, Butler, Adam, Cho, Juok, Dalgliesh, Gillian L., Galappaththige, Danushka, Greenman, Chris, Hardy, Claire, Jia, Mingming, Latimer, Calli, Lau, King Wai, Marshall, John, McLaren, Stuart, Menzies, Andrew, Mudie, Laura, Stebbings, Lucy, Largaespada, David A., Wessels, L.F.A., Richard, Stephane, Kahnoski, Richard J, Anema, John, Tuveson, David A., Perez-Mancera, Pedro A., Mustonen, Ville, Fischer, Andrej, Adams, David J., Rust, Alistair, Chan-on, Waraporn, Subimerb, Chutima, Dykema, Karl, Furge, Kyle, Campbell, Peter J., Teh, Bin Tean, Stratton, Michael R., Futreal, P. Andrew
Publicado 2011