The role of carbonic anhydrase IX in cancer development: links to hypoxia, acidosis, and beyond

por Pastorekova, Silvia, Gillies, Robert J
Publicado 2019

The proteoglycan-like domain of carbonic anhydrase IX mediates non-catalytic facilitation of lactate transport in cancer cells

por Ames, Samantha, Pastorekova, Silvia, Becker, Holger M.
Publicado 2018

Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses

por Obacz, Joanna, Pastorekova, Silvia, Vojtesek, Borek, Hrstka, Roman
Publicado 2013

Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors

por Sedlakova, Olga, Svastova, Eliska, Takacova, Martina, Kopacek, Juraj, Pastorek, Jaromir, Pastorekova, Silvia
Publicado 2014

Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models

por Bullova, Petra, Cougnoux, Antony, Abunimer, Luma, Kopacek, Juraj, Pastorekova, Silvia, Pacak, Karel
Publicado 2016

Understanding metabolic alterations and heterogeneity in cancer progression through validated immunodetection of key molecular components: a case of carbonic anhydrase IX

por Takacova, Martina, Kajanova, Ivana, Kolarcikova, Maria, Lapinova, Jana, Zatovicova, Miriam, Pastorekova, Silvia
Publicado 2022

Cancer-associated S100P protein binds and inactivates p53, permits therapy-induced senescence and supports chemoresistance

por Gibadulinova, Adriana, Pastorek, Michal, Filipcik, Pavel, Radvak, Peter, Csaderova, Lucia, Vojtesek, Borivoj, Pastorekova, Silvia
Publicado 2016

ADAM10 mediates shedding of carbonic anhydrase IX ectodomain non-redundantly to ADAM17

por Zatovicova, Miriam, Kajanova, Ivana, Takacova, Martina, Jelenska, Lenka, Sedlakova, Olga, Labudova, Martina, Pastorekova, Silvia
Publicado 2022

Expression of carbonic anhydrases IX and XII during mouse embryonic development

por Kallio, Heini, Pastorekova, Silvia, Pastorek, Jaromir, Waheed, Abdul, Sly, William S, Mannisto, Susanna, Heikinheimo, Markku, Parkkila, Seppo
Publicado 2006

The effect of carbonic anhydrase IX on focal contacts during cell spreading and migration

por Csaderova, Lucia, Debreova, Michaela, Radvak, Peter, Stano, Matej, Vrestiakova, Magdalena, Kopacek, Juraj, Pastorekova, Silvia, Svastova, Eliska
Publicado 2013

Anti-chondroitin sulfate proteoglycan 4-specific antibodies modify the effects of vemurafenib on melanoma cells differentially in normoxia and hypoxia

por PUCCIARELLI, DANIELA, LENGGER, NINA, TAKACOVA, MARTINA, CSADEROVA, LUCIA, BARTOSOVA, MARIA, BREITENEDER, HEIMO, PASTOREKOVA, SILVIA, HAFNER, CHRISTINE
Publicado 2015

Type 1 Sodium Calcium Exchanger Forms a Complex with Carbonic Anhydrase IX and Via Reverse Mode Activity Contributes to pH Control in Hypoxic Tumors

por Liskova, Veronika, Hudecova, Sona, Lencesova, Lubomira, Iuliano, Filippo, Sirova, Marta, Ondrias, Karol, Pastorekova, Silvia, Krizanova, Olga
Publicado 2019

CAIX-Mediated Control of LIN28/let-7 Axis Contributes to Metabolic Adaptation of Breast Cancer Cells to Hypoxia

por Gibadulinova, Adriana, Bullova, Petra, Strnad, Hynek, Pohlodek, Kamil, Jurkovicova, Dana, Takacova, Martina, Pastorekova, Silvia, Svastova, Eliska
Publicado 2020

Dexamethasone downregulates expression of carbonic anhydrase IX via HIF-1α and NF-κB-dependent mechanisms

por Simko, Veronika, Takacova, Martina, Debreova, Michaela, Laposova, Katarina, Ondriskova-Panisova, Elena, Pastorekova, Silvia, Csaderova, Lucia, Pastorek, Jaromir
Publicado 2016

Carnosine inhibits carbonic anhydrase IX-mediated extracellular acidosis and suppresses growth of HeLa tumor xenografts

por Ditte, Zuzana, Ditte, Peter, Labudova, Martina, Simko, Veronika, Iuliano, Filippo, Zatovicova, Miriam, Csaderova, Lucia, Pastorekova, Silvia, Pastorek, Jaromir
Publicado 2014

Apoptosis-induced ectodomain shedding of hypoxia-regulated carbonic anhydrase IX from tumor cells: a double-edged response to chemotherapy

por Vidlickova, Ivana, Dequiedt, Franck, Jelenska, Lenka, Sedlakova, Olga, Pastorek, Michal, Stuchlik, Stanislav, Pastorek, Jaromir, Zatovicova, Miriam, Pastorekova, Silvia
Publicado 2016

Hypoxia induces cancer-associated cAMP/PKA signalling through HIF-mediated transcriptional control of adenylyl cyclases VI and VII

por Simko, Veronika, Iuliano, Filippo, Sevcikova, Andrea, Labudova, Martina, Barathova, Monika, Radvak, Peter, Pastorekova, Silvia, Pastorek, Jaromir, Csaderova, Lucia
Publicado 2017

Lactate stimulates CA IX expression in normoxic cancer cells

por Panisova, Elena, Kery, Martin, Sedlakova, Olga, Brisson, Lucie, Debreova, Michaela, Sboarina, Martina, Sonveaux, Pierre, Pastorekova, Silvia, Svastova, Eliska
Publicado 2017

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer

por Avnet, Sofia, Baldini, Nicola, Brisson, Lucie, Pedersen, Stine Falsig, Porporato, Paolo E., Sonveaux, Pierre, Szabadkai, Gyorgy, Pastorekova, Silvia
Publicado 2019

Carbonic anhydrase IX in oligodendroglial brain tumors

por Järvelä, Sally, Parkkila, Seppo, Bragge, Helena, Kähkönen, Marketta, Parkkila, Anna-Kaisa, Soini, Ylermi, Pastorekova, Silvia, Pastorek, Jaromir, Haapasalo, Hannu
Publicado 2008