The amyloid-β isoform pattern in cerebrospinal fluid in familial PSEN1 M139T- and L286P-associated Alzheimer's disease

por PORTELIUS, ERIK, FORTEA, JUAN, MOLINUEVO, JOSE LUIS, GUSTAVSSON, MIKAEL K., ANDREASSON, ULF, SANCHEZ-VALLE, RAQUEL
Publicado 2012

A novel Aβ isoform pattern in CSF reflects γ-secretase inhibition in Alzheimer disease

por Portelius, Erik, Dean, Robert A, Gustavsson, Mikael K, Andreasson, Ulf, Zetterberg, Henrik, Siemers, Eric, Blennow, Kaj
Publicado 2010

APLP1 as a cerebrospinal fluid biomarker for γ-secretase modulator treatment

por Sjödin, Simon, Andersson, Kerstin K. A., Mercken, Marc, Zetterberg, Henrik, Borghys, Herman, Blennow, Kaj, Portelius, Erik
Publicado 2015

Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's disease

por Mattsson, Niklas, Insel, Philip S, Palmqvist, Sebastian, Portelius, Erik, Zetterberg, Henrik, Weiner, Michael, Blennow, Kaj, Hansson, Oskar
Publicado 2016

CSF neurofilament light concentration is increased in presymptomatic CHMP2B mutation carriers

por Rostgaard, Nina, Roos, Peter, Portelius, Erik, Blennow, Kaj, Zetterberg, Henrik, Simonsen, Anja H., Nielsen, Jørgen E.
Publicado 2018

Lumbar and ventricular CSF concentrations of extracellular matrix proteins before and after shunt surgery in idiopathic normal pressure hydrocephalus

por Minta, Karolina, Jeppsson, Anna, Brinkmalm, Gunnar, Portelius, Erik, Zetterberg, Henrik, Blennow, Kaj, Tullberg, Mats, Andreasson, Ulf
Publicado 2021

Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer’s disease

por Dansson, Hákon Valur, Stempfle, Lena, Egilsdóttir, Hildur, Schliep, Alexander, Portelius, Erik, Blennow, Kaj, Zetterberg, Henrik, Johansson, Fredrik D.
Publicado 2021

Effect of physical exercise on markers of neuronal dysfunction in cerebrospinal fluid in patients with Alzheimer's disease

por Jensen, Camilla Steen, Portelius, Erik, Høgh, Peter, Wermuth, Lene, Blennow, Kaj, Zetterberg, Henrik, Hasselbalch, Steen Gregers, Simonsen, Anja Hviid
Publicado 2017

Confounding Factors Influencing Amyloid Beta Concentration in Cerebrospinal Fluid

por Bjerke, Maria, Portelius, Erik, Minthon, Lennart, Wallin, Anders, Anckarsäter, Henrik, Anckarsäter, Rolf, Andreasen, Niels, Zetterberg, Henrik, Andreasson, Ulf, Blennow, Kaj
Publicado 2010

The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer’s disease

por Kvartsberg, Hlin, Lashley, Tammaryn, Murray, Christina E., Brinkmalm, Gunnar, Cullen, Nicholas C., Höglund, Kina, Zetterberg, Henrik, Blennow, Kaj, Portelius, Erik
Publicado 2018

Tau oligomers in cerebrospinal fluid in Alzheimer's disease

por Sengupta, Urmi, Portelius, Erik, Hansson, Oskar, Farmer, Kathleen, Castillo‐Carranza, Diana, Woltjer, Randall, Zetterberg, Henrik, Galasko, Douglas, Blennow, Kaj, Kayed, Rakez
Publicado 2017

Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer’s Disease

por Brownjohn, Philip W., Smith, James, Portelius, Erik, Serneels, Lutgarde, Kvartsberg, Hlin, De Strooper, Bart, Blennow, Kaj, Zetterberg, Henrik, Livesey, Frederick J.
Publicado 2017

Human cerebrospinal fluid 6E10-immunoreactive protein species contain amyloid precursor protein fragments

por Grant, Marianne K. O., Handoko, Maureen, Rozga, Malgorzata, Brinkmalm, Gunnar, Portelius, Erik, Blennow, Kaj, Ashe, Karen H., Zahs, Kathleen R., Liu, Peng
Publicado 2019

Prediction of Outcome After Endovascular Embolectomy in Anterior Circulation Stroke Using Biomarkers

por Pujol-Calderón, Fani, Zetterberg, Henrik, Portelius, Erik, Löwhagen Hendén, Pia, Rentzos, Alexandros, Karlsson, Jan-Erik, Höglund, Kina, Blennow, Kaj, Rosengren, Lars E.
Publicado 2021

Cerebrospinal fluid biomarker panel for synaptic dysfunction in Alzheimer's disease

por Nilsson, Johanna, Gobom, Johan, Sjödin, Simon, Brinkmalm, Gunnar, Ashton, Nicholas J., Svensson, Johan, Johansson, Per, Portelius, Erik, Zetterberg, Henrik, Blennow, Kaj, Brinkmalm, Ann
Publicado 2021

Neurofilaments can differentiate ALS subgroups and ALS from common diagnostic mimics

por Behzadi, Arvin, Pujol-Calderón, Fani, Tjust, Anton E., Wuolikainen, Anna, Höglund, Kina, Forsberg, Karin, Portelius, Erik, Blennow, Kaj, Zetterberg, Henrik, Andersen, Peter Munch
Publicado 2021

Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer’s disease

por Hellwig, Konstantin, Kvartsberg, Hlin, Portelius, Erik, Andreasson, Ulf, Oberstein, Timo Jan, Lewczuk, Piotr, Blennow, Kaj, Kornhuber, Johannes, Maler, Juan Manuel, Zetterberg, Henrik, Spitzer, Philipp
Publicado 2015

Dynamics of cerebrospinal fluid levels of matrix metalloproteinases in human traumatic brain injury

por Minta, Karolina, Brinkmalm, Gunnar, Al Nimer, Faiez, Thelin, Eric P., Piehl, Fredrik, Tullberg, Mats, Jeppsson, Anna, Portelius, Erik, Zetterberg, Henrik, Blennow, Kaj, Andreasson, Ulf
Publicado 2020

Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by Calpain-1 and prolyl endopeptidase

por Becker, Bruno, Nazir, Faisal Hayat, Brinkmalm, Gunnar, Camporesi, Elena, Kvartsberg, Hlin, Portelius, Erik, Boström, Martina, Kalm, Marie, Höglund, Kina, Olsson, Maria, Zetterberg, Henrik, Blennow, Kaj
Publicado 2018

β-site amyloid precursor protein-cleaving enzyme 1(BACE1) inhibitor treatment induces Aβ5-X peptides through alternative amyloid precursor protein cleavage

por Portelius, Erik, Dean, Robert A, Andreasson, Ulf, Mattsson, Niklas, Westerlund, Anni, Olsson, Maria, Demattos, Ronald Bradley, Racke, Margaret M, Zetterberg, Henrik, May, Patrick C, Blennow, Kaj
Publicado 2014