PERK promotes immunosuppressive M2 macrophage phenotype by metabolic reprogramming and epigenetic modifications through the PERK-ATF4-PSAT1 axis

por Pratap, Uday P., Vadlamudi, Ratna K.
Publicado 2022

Editorial: Molecular targeting of the tumor microenvironment for therapeutics in cancer metastasis

por Dasari, Subramanyam, Pitta Venkata, Prabhakar, Pratap, Uday P., Ram Kumar, Ram Mohan
Publicado 2023

Sex-Based Differences in the Cytokine Production and Intracellular Signaling Pathways in Patients With Rheumatoid Arthritis

por PRATAP, Uday P., HIMA, Lalgi, KANNAN, Thangamani, THYAGARAJAN, Chadrasekaran, PRIYANKA, Hannah P., VASANTHAREKHA, Ramasamy, PUSHPARANI, Anand, THYAGARAJAN, Srinivasan
Publicado 2020

Development and Characterization of Inducible Astrocyte-Specific Aromatase Knockout Mice

por Wang, Jing, Pratap, Uday P., Lu, Yujiao, Sareddy, Gangadhara R., Tekmal, Rajeshwar R., Vadlamudi, Ratna K., Brann, Darrell W.
Publicado 2023

Neuron-Derived Estrogen—A Key Neuromodulator in Synaptic Function and Memory

por Brann, Darrell W., Lu, Yujiao, Wang, Jing, Sareddy, Gangadhara R., Pratap, Uday P., Zhang, Quanguang, Tekmal, Rajeshwar R., Vadlamudi, Ratna K.
Publicado 2021

Brain-Derived Estrogen and Neurological Disorders

por Brann, Darrell W., Lu, Yujiao, Wang, Jing, Sareddy, Gangadhara R., Pratap, Uday P., Zhang, Quanguang, Tekmal, Rajeshwar R., Vadlamudi, Ratna K.
Publicado 2022

Brain-derived estrogen and neural function

por Brann, Darrell W., Lu, Yujiao, Wang, Jing, Zhang, Quanguang, Thakkar, Roshni, Sareddy, Gangadhara R., Pratap, Uday P., Tekmal, Rajeshwar R., Vadlamudi, Ratna K.
Publicado 2022

Neuron-Derived Estrogen Is Critical for Astrocyte Activation and Neuroprotection of the Ischemic Brain

por Lu, Yujiao, Sareddy, Gangadhara R., Wang, Jing, Zhang, Quanguang, Tang, Fu-Lei, Pratap, Uday P., Tekmal, Rajeshwar R., Vadlamudi, Ratna K., Brann, Darrell W.
Publicado 2020

Regulation and Role of Neuron-Derived Hemoglobin in the Mouse Hippocampus

por Lu, Yujiao, Wang, Jing, Tang, Fulei, Pratap, Uday P., Sareddy, Gangadhara R., Dhandapani, Krishnan M., Capuano, Ana, Arvanitakis, Zoe, Vadlamudi, Ratna K., Brann, Darrell W.
Publicado 2022

Therapeutic Targeting of Ovarian Cancer Stem Cells Using Estrogen Receptor Beta Agonist

por He, Yi, Alejo, Salvador, Venkata, Prabhakar Pitta, Johnson, Jessica D., Loeffel, Ilanna, Pratap, Uday P., Zou, Yi, Lai, Zhao, Tekmal, Rajeshwar R., Kost, Edward R., Sareddy, Gangadhara R.
Publicado 2022

Interaction of transcription factor AP‐2 gamma with proto‐oncogene PELP1 promotes tumorigenesis by enhancing RET signaling

por Liu, Junhao, Liu, Zexuan, Li, Mengxing, Tang, Weiwei, Pratap, Uday P., Luo, Yiliao, Altwegg, Kristin A., Li, Xiaonan, Zou, Yi, Zhu, Hong, Sareddy, Gangadhara R., Viswanadhapalli, Suryavathi, Vadlamudi, Ratna K.
Publicado 2021

PELP1 promotes glioblastoma progression by enhancing Wnt/β-catenin signaling

por Sareddy, Gangadhara R, Pratap, Uday P, Viswanadhapalli, Suryavathi, Venkata, Prabhakar Pitta, Nair, Binoj C, Krishnan, Samaya Rajeshwari, Zheng, Siyuan, Gilbert, Andrea R, Brenner, Andrew J, Brann, Darrell W, Vadlamudi, Ratna K
Publicado 2019

Targeting PELP1 oncogenic signaling in TNBC with the small molecule inhibitor SMIP34

por Altwegg, Kristin A., Pratap, Uday P., Liu, Zexuan, Liu, Junhao, Sanchez, John R., Yang, Xue, Ebrahimi, Behnam, Panneerdoss, Durga Meenakshi, Li, Xiaonan, Sareddy, Gangadhara R., Viswanadhapalli, Suryavathi, Rao, Manjeet K., Vadlamudi, Ratna K.
Publicado 2023

Histone deacetylase inhibitors enhance estrogen receptor beta expression and augment agonist-mediated tumor suppression in glioblastoma

por Pratap, Uday P, Sareddy, Gangadhara R, Liu, Zexuan, Venkata, Prabhakar Pitta, Liu, Junhao, Tang, Weiwei, Altwegg, Kristin A, Ebrahimi, Behnam, Li, Xiaonan, Tekmal, Rajeshwar R, Viswanadhapalli, Suryavathi, McHardy, Stanton, Brenner, Andrew J, Vadlamudi, Ratna K
Publicado 2021

SETDB1 interactions with PELP1 contributes to breast cancer endocrine therapy resistance

por Liu, Zexuan, Liu, Junhao, Ebrahimi, Behnam, Pratap, Uday P., He, Yi, Altwegg, Kristin A., Tang, Weiwei, Li, Xiaonan, Lai, Zhao, Chen, Yidong, Shen, Liangfang, Sareddy, Gangadhara R., Viswanadhapalli, Suryavathi, Tekmal, Rajeshwar R., Rao, Manjeet K., Vadlamudi, Ratna K.
Publicado 2022

Inhibition of LIFR Blocks Adiposity-Driven Endometrioid Endometrial Cancer Growth

por Blankenship, Logan, Pratap, Uday P., Yang, Xue, Liu, Zexuan, Altwegg, Kristin A., Santhamma, Bindu, Ramasamy, Kumaraguruparan, Konda, Swapna, Chen, Yidong, Lai, Zhao, Zheng, Siyuan, Sareddy, Gangadhara R., Valente, Philip T., Kost, Edward R., Nair, Hareesh B., Tekmal, Rajeshwar R., Vadlamudi, Ratna K., Viswanadhapalli, Suryavathi
Publicado 2022

Estrogen receptor coregulator binding modulator (ERX-11) enhances the activity of CDK4/6 inhibitors against estrogen receptor-positive breast cancers

por Viswanadhapalli, Suryavathi, Ma, Shihong, Sareddy, Gangadhara Reddy, Lee, Tae-Kyung, Li, Mengxing, Gilbreath, Collin, Liu, Xihui, Luo, Yiliao, Pratap, Uday P., Zhou, Mei, Blatt, Eliot B., Kassees, Kara, Arteaga, Carlos, Alluri, Prasanna, Rao, Manjeet, Weintraub, Susan T., Tekmal, Rajeshwar Rao, Ahn, Jung-Mo, Raj, Ganesh V., Vadlamudi, Ratna K.
Publicado 2019

LIF/LIFR oncogenic signaling is a novel therapeutic target in endometrial cancer

por Tang, Weiwei, Ramasamy, Kumaraguruparan, Pillai, Sureshkumar M. A., Santhamma, Bindu, Konda, Swapna, Pitta Venkata, Prabhakar, Blankenship, Logan, Liu, Junhao, Liu, Zexuan, Altwegg, Kristin A., Ebrahimi, Behnam, Pratap, Uday P., Li, Xiaonan, Valente, Philip T., Kost, Edward, Sareddy, Gangadhara R., Vadlamudi, Ratna K., Nair, Hareesh B., Tekmal, Rajeshwar R., Viswanadhapalli, Suryavathi
Publicado 2021

LIFR inhibition enhances the therapeutic efficacy of HDAC inhibitors in triple negative breast cancer

por Li, Mengxing, Viswanadhapalli, Suryavathi, Santhamma, Bindu, Pratap, Uday P., Luo, Yiliao, Liu, Junhao, Altwegg, Kristin A., Tang, Weiwei, Liu, Zexuan, Li, Xiaonan, Ebrahimi, Behnam, Yan, Hui, Zou, Yi, Konda, Swapna, Sareddy, Gangadhara R., Xu, Zhenming, Chen, Yidong, Rao, Manjeet K., Brenner, Andrew J., Kaklamani, Virginia G., Tekmal, Rajeshwar R., Ahmed, Gulzar, Raj, Ganesh V., Nickisch, Klaus J., Nair, Hareesh B., Vadlamudi, Ratna K.
Publicado 2021

Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress

por Liu, Xihui, Viswanadhapalli, Suryavathi, Kumar, Shourya, Lee, Tae-Kyung, Moore, Andrew, Ma, Shihong, Chen, Liping, Hsieh, Michael, Li, Mengxing, Sareddy, Gangadhara R., Parra, Karla, Blatt, Eliot B., Reese, Tanner C., Zhao, Yuting, Chang, Annabel, Yan, Hui, Xu, Zhenming, Pratap, Uday P., Liu, Zexuan, Roggero, Carlos M., Tan, Zhenqiu, Weintraub, Susan T., Peng, Yan, Tekmal, Rajeshwar R., Arteaga, Carlos L., Lippincott-Schwartz, Jennifer, Vadlamudi, Ratna K., Ahn, Jung-Mo, Raj, Ganesh V.
Publicado 2022