Enzymatically Produced Pools of Canonical and Dicer-Substrate siRNA Molecules Display Comparable Gene Silencing and Antiviral Activities against Herpes Simplex Virus

por Romanovskaya, Alesia, Paavilainen, Henrik, Nygårdas, Michaela, Bamford, Dennis H., Hukkanen, Veijo, Poranen, Minna M.
Publicado 2012

A Herpes Simplex Virus-Derived Replicative Vector Expressing LIF Limits Experimental Demyelinating Disease and Modulates Autoimmunity

por Nygårdas, Michaela, Paavilainen, Henrik, Müther, Nadine, Nagel, Claus-Henning, Röyttä, Matias, Sodeik, Beate, Hukkanen, Veijo
Publicado 2013

Attenuated Replication-Competent Herpes Simplex Virus Expressing an ECM-Modifying Transgene Hyaluronan Synthase 2 of Naked Mole Rat in Oncolytic Gene Therapy

por Palomäki, Jussi, Kalke, Kiira, Orpana, Julius, Lund, Liisa, Frejborg, Fanny, Paavilainen, Henrik, Järveläinen, Hannu, Hukkanen, Veijo
Publicado 2023

The In Vitro Replication, Spread, and Oncolytic Potential of Finnish Circulating Strains of Herpes Simplex Virus Type 1

por Kalke, Kiira, Orpana, Julius, Lasanen, Tuomas, Esparta, Olaya, Lund, Liisa M., Frejborg, Fanny, Vuorinen, Tytti, Paavilainen, Henrik, Hukkanen, Veijo
Publicado 2022

Swarms of chemically modified antiviral siRNA targeting herpes simplex virus infection in human corneal epithelial cells

por Kalke, Kiira, Lund, Liisa M., Nyman, Marie C., Levanova, Alesia A., Urtti, Arto, Poranen, Minna M., Hukkanen, Veijo, Paavilainen, Henrik
Publicado 2022

Comparison of Herpes Simplex Virus 1 Strains Circulating in Finland Demonstrates the Uncoupling of Whole-Genome Relatedness and Phenotypic Outcomes of Viral Infection

por Bowen, Christopher D., Paavilainen, Henrik, Renner, Daniel W., Palomäki, Jussi, Lehtinen, Jenni, Vuorinen, Tytti, Norberg, Peter, Hukkanen, Veijo, Szpara, Moriah L.
Publicado 2019

Enzymatically synthesized 2′-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity

por Levanova, Alesia A., Kalke, Kiira M., Lund, Liisa M., Sipari, Nina, Sadeghi, Mohammadreza, Nyman, Marie C., Paavilainen, Henrik, Hukkanen, Veijo, Poranen, Minna M.
Publicado 2020

Personalized Cancer Vaccine Platform for Clinically Relevant Oncolytic Enveloped Viruses

por Ylösmäki, Erkko, Malorzo, Cristina, Capasso, Cristian, Honkasalo, Oona, Fusciello, Manlio, Martins, Beatriz, Ylösmäki, Leena, Louna, Antti, Feola, Sara, Paavilainen, Henrik, Peltonen, Karita, Hukkanen, Veijo, Viitala, Tapani, Cerullo, Vincenzo
Publicado 2018

Herpes Simplex Virus Type 1 Clinical Isolates Respond to UL29-Targeted siRNA Swarm Treatment Independent of Their Acyclovir Sensitivity

por Kalke, Kiira, Lehtinen, Jenni, Gnjatovic, Jelena, Lund, Liisa M., Nyman, Marie C., Paavilainen, Henrik, Orpana, Julius, Lasanen, Tuomas, Frejborg, Fanny, Levanova, Alesia A., Vuorinen, Tytti, Poranen, Minna M., Hukkanen, Veijo
Publicado 2020

Novel activities of safe-in-human broad-spectrum antiviral agents

por Ianevski, Aleksandr, Zusinaite, Eva, Kuivanen, Suvi, Strand, Mårten, Lysvand, Hilde, Teppor, Mona, Kakkola, Laura, Paavilainen, Henrik, Laajala, Mira, Kallio-Kokko, Hannimari, Valkonen, Miia, Kantele, Anu, Telling, Kaidi, Lutsar, Irja, Letjuka, Pille, Metelitsa, Natalja, Oksenych, Valentyn, Bjørås, Magnar, Nordbø, Svein Arne, Dumpis, Uga, Vitkauskiene, Astra, Öhrmalm, Christina, Bondeson, Kåre, Bergqvist, Anders, Aittokallio, Tero, Cox, Rebecca J., Evander, Magnus, Hukkanen, Veijo, Marjomaki, Varpu, Julkunen, Ilkka, Vapalahti, Olli, Tenson, Tanel, Merits, Andres, Kainov, Denis
Publicado 2018

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins

por Bulanova, Daria, Ianevski, Aleksandr, Bugai, Andrii, Akimov, Yevhen, Kuivanen, Suvi, Paavilainen, Henrik, Kakkola, Laura, Nandania, Jatin, Turunen, Laura, Ohman, Tiina, Ala-Hongisto, Hanna, Pesonen, Hanna M., Kuisma, Marika S., Honkimaa, Anni, Walton, Emma L., Oksenych, Valentyn, Lorey, Martina B., Guschin, Dmitry, Shim, Jungmin, Kim, Jinhee, Than, Thoa T., Chang, So Young, Hukkanen, Veijo, Kulesskiy, Evgeny, Marjomaki, Varpu S., Julkunen, Ilkka, Nyman, Tuula A., Matikainen, Sampsa, Saarela, Jani S., Sane, Famara, Hober, Didier, Gabriel, Gülsah, De Brabander, Jef K., Martikainen, Miika, Windisch, Marc P., Min, Ji-Young, Bruzzone, Roberto, Aittokallio, Tero, Vähä-Koskela, Markus, Vapalahti, Olli, Pulk, Arto, Velagapudi, Vidya, Kainov, Denis E.
Publicado 2017