Targeting Genetic Modifiers of HBG Gene Expression in Sickle Cell Disease: The miRNA Option

por Starlard-Davenport, Athena, Gu, Qingqing, Pace, Betty S.
Publicado 2022

Sickle Cell Disease: Genetics, Cellular and Molecular Mechanisms, and Therapies

por Pace, Betty S., Ofori-Acquah, Solomon F., Peterson, Kenneth R.
Publicado 2012

Characterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation

por Li, Biaoru, Ding, Lianghao, Li, Wei, Story, Michael D, Pace, Betty S
Publicado 2012

Ethanol Exposure Induces Neonatal Neurodegeneration by Enhancing CB1R Exon1 Histone H4K8 Acetylation and Up-regulating CB1R Function causing Neurobehavioral Abnormalities in Adult...

por Subbanna, Shivakumar, Nagre, Nagaraja N., Umapathy, Nagavedi S., Pace, Betty S., Basavarajappa, Balapal S.
Publicado 2015

MIR29B mediates epigenetic mechanisms of HBG gene activation

por Starlard‐Davenport, Athena, Smith, Alana, Vu, Luan, Li, Biaoru, Pace, Betty S.
Publicado 2019

Stroke in a Child with Hemoglobin SC Disease: A Case Report Describing use of Hydroxyurea after Transfusion Therapy

por Fridlyand, Diana, Wilder, Caroline, Clay, E. Leila Jerome, Gilbert, Bruce, Pace, Betty S.
Publicado 2017

Peer mentoring to support career advancement among underrepresented minority faculty in the programs to increase diversity among individuals engaged in health-related research (PRI...

por Coleman, Taylor M., Starlard-Davenport, Athena, Onwuemene, Oluwatoyosi A., Stepleman, Lara M., Pace, Betty S.
Publicado 2023

Regulation of Gγ-Globin Gene by ATF2 and Its Associated Proteins through the cAMP-Response Element

por Liu, Li, Karmakar, Subhradip, Dhar, Ruby, Mahajan, Milind, Choudhury, Alina, Weissman, Sherman, Pace, Betty S.
Publicado 2013

FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors

por Makala, Levi, Di Maro, Salvatore, Lou, Tzu-Fang, Sivanand, Sharanya, Ahn, Jung-Mo, Pace, Betty S.
Publicado 2012

Characterization of Transcription Factor Networks Involved in Umbilical Cord Blood CD34(+) Stem Cells-Derived Erythropoiesis

por Li, Biaoru, Ding, Lianghao, Yang, Chinrang, Kang, Baolin, Liu, Li, Story, Michael D., Pace, Betty S.
Publicado 2014

Streptococcus pneumoniae and Its Virulence Factors H(2)O(2) and Pneumolysin Are Potent Mediators of the Acute Chest Syndrome in Sickle Cell Disease

por Gonzales, Joyce, Chakraborty, Trinad, Romero, Maritza, Mraheil, Mobarak Abu, Kutlar, Abdullah, Pace, Betty, Lucas, Rudolf
Publicado 2021

Salubrinal induces fetal hemoglobin expression via the stress-signaling pathway in human sickle erythroid progenitors and sickle cell disease mice

por Lopez, Nicole H., Li, Biaoru, Palani, Chithra, Siddaramappa, Umapathy, Takezaki, Mayuko, Xu, Hongyan, Zhi, Wenbo, Pace, Betty S.
Publicado 2022

MicroRNA29B induces fetal hemoglobin via inhibition of the HBG repressor protein MYB in vitro and in humanized sickle cell mice

por Gu, Qingqing, Palani, Chithra D., Smith, Alana, Li, Biaori, Amos-Abanyie, Ernestine Kubi, Ogu, Ugochi, Lu, Lu, Pace, Betty S., Starlard-Davenport, Athena
Publicado 2022

UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development

por Cai, Yafei, Pi, Wenhu, Sivaprakasam, Satish, Zhu, Xiaobin, Zhang, Mingsheng, Chen, Jijun, Makala, Levi, Lu, Chunwan, Wu, Jianchu, Teng, Yong, Pace, Betty, Tuan, Dorothy, Singh, Nagendra, Li, Honglin
Publicado 2015

A Cell-Based High-Throughput Screen for Novel Chemical Inducers of Fetal Hemoglobin for Treatment of Hemoglobinopathies

por Peterson, Kenneth R., Costa, Flávia C., Fedosyuk, Halyna, Neades, Renee Y., Chazelle, Allen M., Zelenchuk, Lesya, Fonteles, Andrea H., Dalal, Parmita, Roy, Anuradha, Chaguturu, Rathnam, Li, Biaoru, Pace, Betty S.
Publicado 2014

The gut microbiome in sickle cell disease: Characterization and potential implications

por Brim, Hassan, Taylor, James, Abbas, Muneer, Vilmenay, Kimberly, Daremipouran, Mohammad, Varma, Sudhir, Lee, Edward, Pace, Betty, Song-Naba, Waogwende L., Gupta, Kalpna, Nekhai, Sergei, O’Neil, Patricia, Ashktorab, Hassan
Publicado 2021

Novel Inducers of Fetal Globin Identified through High Throughput Screening (HTS) Are Active In Vivo in Anemic Baboons and Transgenic Mice

por Boosalis, Michael S., Sangerman, Jose I., White, Gary L., Wolf, Roman F., Shen, Ling, Dai, Yan, White, Emily, Makala, Levi H., Li, Biaoru, Pace, Betty S., Nouraie, Mehdi, Faller, Douglas V., Perrine, Susan P.
Publicado 2015

Global Genetic Architecture of an Erythroid Quantitative Trait Locus, HMIP-2

por Menzel, Stephan, Rooks, Helen, Zelenika, Diana, Mtatiro, Siana N, Gnanakulasekaran, Akshala, Drasar, Emma, Cox, Sharon, Liu, Li, Masood, Mariam, Silver, Nicholas, Garner, Chad, Vasavda, Nisha, Howard, Jo, Makani, Julie, Adekile, Adekunle, Pace, Betty, Spector, Tim, Farrall, Martin, Lathrop, Mark, Thein, Swee Lay
Publicado 2014

Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential

por Nakao, Tetsushi, Bick, Alexander G., Taub, Margaret A., Zekavat, Seyedeh M., Uddin, Md M., Niroula, Abhishek, Carty, Cara L., Lane, John, Honigberg, Michael C., Weinstock, Joshua S., Pampana, Akhil, Gibson, Christopher J., Griffin, Gabriel K., Clarke, Shoa L., Bhattacharya, Romit, Assimes, Themistocles L., Emery, Leslie S., Stilp, Adrienne M., Wong, Quenna, Broome, Jai, Laurie, Cecelia A., Khan, Alyna T., Smith, Albert V., Blackwell, Thomas W., Codd, Veryan, Nelson, Christopher P., Yoneda, Zachary T., Peralta, Juan M., Bowden, Donald W., Irvin, Marguerite R., Boorgula, Meher, Zhao, Wei, Yanek, Lisa R., Wiggins, Kerri L., Hixson, James E., Gu, C. Charles, Peloso, Gina M., Roden, Dan M., Reupena, Muagututi’a S., Hwu, Chii-Min, DeMeo, Dawn L., North, Kari E., Kelly, Shannon, Musani, Solomon K., Bis, Joshua C., Lloyd-Jones, Donald M., Johnsen, Jill M., Preuss, Michael, Tracy, Russell P., Peyser, Patricia A., Qiao, Dandi, Desai, Pinkal, Curran, Joanne E., Freedman, Barry I., Tiwari, Hemant K., Chavan, Sameer, Smith, Jennifer A., Smith, Nicholas L., Kelly, Tanika N., Hidalgo, Bertha, Cupples, L. Adrienne, Weeks, Daniel E., Hawley, Nicola L., Minster, Ryan L., Deka, Ranjan, Naseri, Take T., de las Fuentes, Lisa, Raffield, Laura M., Morrison, Alanna C., Vries, Paul S., Ballantyne, Christie M., Kenny, Eimear E., Rich, Stephen S., Whitsel, Eric A., Cho, Michael H., Shoemaker, M. Benjamin, Pace, Betty S., Blangero, John, Palmer, Nicholette D., Mitchell, Braxton D., Shuldiner, Alan R., Barnes, Kathleen C., Redline, Susan, Kardia, Sharon L.R., Abecasis, Gonçalo R., Becker, Lewis C., Heckbert, Susan R., He, Jiang, Post, Wendy, Arnett, Donna K., Vasan, Ramachandran S., Darbar, Dawood, Weiss, Scott T., McGarvey, Stephen T., de Andrade, Mariza, Chen, Yii-Der Ida, Kaplan, Robert C., Meyers, Deborah A., Custer, Brian S., Correa, Adolfo, Psaty, Bruce M., Fornage, Myriam, Manson, JoAnn E., Boerwinkle, Eric, Konkle, Barbara A., Loos, Ruth J.F., Rotter, Jerome I., Silverman, Edwin K., Kooperberg, Charles, Danesh, John, Samani, Nilesh J., Jaiswal, Siddhartha, Libby, Peter, Ellinor, Patrick T., Pankratz, Nathan, Ebert, Benjamin L., Reiner, Alexander P., Mathias, Rasika A., Do, Ron, Natarajan, Pradeep
Publicado 2022