Ferulic acid derivatives block coronaviruses HCoV-229E and SARS-CoV-2 replication in vitro

por Pasquereau, Sébastien, Galais, Mathilde, Bellefroid, Maxime, Pachón Angona, Irene, Morot-Bizot, Stéphanie, Ismaili, Lhassane, Van Lint, Carine, Herbein, Georges
Publicado 2022

Leveraging molecular structure and bioactivity with chemical language models for de novo drug design

por Moret, Michael, Pachon Angona, Irene, Cotos, Leandro, Yan, Shen, Atz, Kenneth, Brunner, Cyrill, Baumgartner, Martin, Grisoni, Francesca, Schneider, Gisbert
Publicado 2023

Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer’s Disease Therapy

por Zribi, Lazhar, Pachòn-Angona, Irene, Bautista-Aguilera, Òscar M., Diez-Iriepa, Daniel, Marco-Contelles, José, Ismaili, Lhassane, Iriepa, Isabel, Chabchoub, Fakher
Publicado 2020

Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives

por Pachón Angona, Irene, Martin, Helene, Daniel, Solene, Moraleda, Ignacio, Bonet, Alexandre, Wnorowski, Artur, Maj, Maciej, Jozwiak, Krzysztof, Iriepa, Isabel, Refouvelet, Bernard, Marco-Contelles, José, Ismaili, Lhassane
Publicado 2020

Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels

por Pachòn Angona, Irene, Daniel, Solene, Martin, Helene, Bonet, Alexandre, Wnorowski, Artur, Maj, Maciej, Jóźwiak, Krzysztof, Silva, Tiago Barros, Refouvelet, Bernard, Borges, Fernanda, Marco-Contelles, José, Ismaili, Lhassane
Publicado 2020

Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy

por Pachón-Angona, Irene, Refouvelet, Bernard, Andrýs, Rudolf, Martin, Helène, Luzet, Vincent, Iriepa, Isabel, Moraleda, Ignacio, Diez-Iriepa, Daniel, Oset-Gasque, María-Jesús, Marco-Contelles, José, Musilek, Kamil, Ismaili, Lhassane
Publicado 2019