Protocol to study sufficiency of cis-regulatory elements in mouse embryonic stem cells using a CRISPR-mediated knockin approach

por Pachano, Tomas, Rada-Iglesias, Alvaro
Publicado 2022

The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

por Crispatzu, Giuliano, Rehimi, Rizwan, Pachano, Tomas, Bleckwehl, Tore, Cruz-Molina, Sara, Xiao, Cally, Mahabir, Esther, Bazzi, Hisham, Rada-Iglesias, Alvaro
Publicado 2021

Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness

por Pachano, Tomas, Sánchez-Gaya, Víctor, Ealo, Thais, Mariner-Faulí, Maria, Bleckwehl, Tore, Asenjo, Helena G., Respuela, Patricia, Cruz-Molina, Sara, Martín, María Muñoz-San, Haro, Endika, van IJcken, Wilfred F. J., Landeira, David, Rada-Iglesias, Alvaro
Publicado 2021

Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells

por Asenjo, Helena G., Alcazar-Fabra, María, Espinosa-Martínez, Mencía, Lopez-Onieva, Lourdes, Gallardo, Amador, Dimitrova, Emilia, Feldmann, Angelika, Pachano, Tomas, Martorell-Marugán, Jordi, Carmona-Sáez, Pedro, Sanchez-Pozo, Antonio, Rada-Iglesias, Álvaro, Klose, Robert J., Landeira, David
Publicado 2023