Histidine is selectively required for the growth of Myc‐dependent dedifferentiation tumours in the Drosophila CNS

por Froldi, Francesca, Pachnis, Panayotis, Szuperák, Milán, Costas, Olivia, Fernando, Tharindu, Gould, Alex P, Cheng, Louise Y
Publicado 2019

Partial N‐acetyl glutamate synthase deficiency presenting as postpartum hyperammonemia: Diagnosis and subsequent pregnancy management

por Abou Haidar, Lea, Pachnis, Panayotis, Gotway, Garrett K., Ni, Min, DeBerardinis, Ralph J., McNutt, Markey C.
Publicado 2023

Compartmentalized metabolism supports midgestation mammalian development

por Solmonson, Ashley, Faubert, Brandon, Gu, Wen, Rao, Aparna, Cowdin, Mitzy A., Menendez-Montes, Ivan, Kelekar, Sherwin, Rogers, Thomas J., Pan, Chunxiao, Guevara, Gerardo, Tarangelo, Amy, Zacharias, Lauren G., Martin-Sandoval, Misty S., Do, Duyen, Pachnis, Panayotis, Dumesnil, Dennis, Mathews, Thomas P., Tasdogan, Alpaslan, Pham, An, Cai, Ling, Zhao, Zhiyu, Ni, Min, Cleaver, Ondine, Sadek, Hesham A., Morrison, Sean J., DeBerardinis, Ralph J.
Publicado 2022

In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors

por Pachnis, Panayotis, Wu, Zheng, Faubert, Brandon, Tasdogan, Alpaslan, Gu, Wen, Shelton, Spencer, Solmonson, Ashley, Rao, Aparna D., Kaushik, Akash K., Rogers, Thomas J., Ubellacker, Jessalyn M., LaVigne, Collette A., Yang, Chendong, Ko, Bookyung, Ramesh, Vijayashree, Sudderth, Jessica, Zacharias, Lauren G., Martin-Sandoval, Misty S., Do, Duyen, Mathews, Thomas P., Zhao, Zhiyu, Mishra, Prashant, Morrison, Sean J., DeBerardinis, Ralph J.
Publicado 2022

In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma

por Kaushik, Akash K., Tarangelo, Amy, Boroughs, Lindsey K., Ragavan, Mukundan, Zhang, Yuanyuan, Wu, Cheng-Yang, Li, Xiangyi, Ahumada, Kristen, Chiang, Jui-Chung, Tcheuyap, Vanina T., Saatchi, Faeze, Do, Quyen N., Yong, Cissy, Rosales, Tracy, Stevens, Christina, Rao, Aparna D., Faubert, Brandon, Pachnis, Panayotis, Zacharias, Lauren G., Vu, Hieu, Cai, Feng, Mathews, Thomas P., Genovese, Giannicola, Slusher, Barbara S., Kapur, Payal, Sun, Xiankai, Merritt, Matthew, Brugarolas, James, DeBerardinis, Ralph J.
Publicado 2022