Use of a charge reducing agent to enable intact mass analysis of cysteine-linked antibody-drug-conjugates by native mass spectrometry

por Pacholarz, Kamila J., Barran, Perdita E.
Publicado 2016

Charge Mediated Compaction and Rearrangement of Gas-Phase Proteins: A Case Study Considering Two Proteins at Opposing Ends of the Structure-Disorder Continuum

por Jhingree, Jacquelyn R., Bellina, Bruno, Pacholarz, Kamila J., Barran, Perdita E.
Publicado 2017

Hybrid mass spectrometry methods reveal lot-to-lot differences and delineate the effects of glycosylation on the tertiary structure of Herceptin®

por Upton, Rosie, Migas, Lukasz G., Pacholarz, Kamila J., Beniston, Richard G., Estdale, Sian, Firth, David, Barran, Perdita E.
Publicado 2019

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

por Jeffreys, Laura N., Pacholarz, Kamila J., Johannissen, Linus O., Girvan, Hazel M., Barran, Perdita E., Voice, Michael W., Munro, Andrew W.
Publicado 2020

Uncoupling conformational states from activity in an allosteric enzyme

por Pisco, João P., de Chiara, Cesira, Pacholarz, Kamila J., Garza-Garcia, Acely, Ogrodowicz, Roksana W., Walker, Philip A., Barran, Perdita E., Smerdon, Stephen J., de Carvalho, Luiz Pedro S.
Publicado 2017

Hybrid Mass Spectrometry Approaches to Determine How L-Histidine Feedback Regulates the Enzyzme MtATP-Phosphoribosyltransferase

por Pacholarz, Kamila J., Burnley, Rebecca J., Jowitt, Thomas A., Ordsmith, Victoria, Pisco, João Pedro, Porrini, Massimiliano, Larrouy-Maumus, Gérald, Garlish, Rachel A., Taylor, Richard J., de Carvalho, Luiz Pedro Sório, Barran, Perdita E.
Publicado 2017

Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes

por Sayers, Sophie R., Beavil, Rebecca L., Fine, Nicholas H. F., Huang, Guo C., Choudhary, Pratik, Pacholarz, Kamila J., Barran, Perdita E., Butterworth, Sam, Mills, Charlotte E., Cruickshank, J. Kennedy, Silvestre, Marta P., Poppitt, Sally D., McGill, Anne-Thea, Lavery, Gareth G., Hodson, David J., Caton, Paul W.
Publicado 2019