Resistance Is Not Futile: The Role of Quorum Sensing Plasticity in Pseudomonas aeruginosa Infections and Its Link to Intrinsic Mechanisms of Antibiotic Resistance

por Simanek, Kayla A., Paczkowski, Jon E.
Publicado 2022

An autoinducer-independent RhlR quorum-sensing receptor enables analysis of RhlR regulation

por McCready, Amelia R., Paczkowski, Jon E., Cong, Jian-Ping, Bassler, Bonnie L.
Publicado 2019

Quorum-sensing synthase mutations re-calibrate autoinducer concentrations in clinical isolates of Pseudomonas aeruginosa to enhance pathogenesis

por Simanek, Kayla A., Schumacher, Megan L., Mallery, Caleb P., Shen, Stella, Li, Lingyun, Paczkowski, Jon E.
Publicado 2023

Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein–Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor...

por Taylor, Isabelle R., Paczkowski, Jon E., Jeffrey, Philip D., Henke, Brad R., Smith, Chari D., Bassler, Bonnie L.
Publicado 2021

The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in Pseudomonas aeruginosa

por Simanek, Kayla A., Taylor, Isabelle R., Richael, Erica K., Lasek-Nesselquist, Erica, Bassler, Bonnie L., Paczkowski, Jon E.
Publicado 2022