Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART

por Gantner, Pierre, Pagliuzza, Amélie, Pardons, Marion, Ramgopal, Moti, Routy, Jean-Pierre, Fromentin, Rémi, Chomont, Nicolas
Publicado 2020

Plasma SARS‐CoV‐2 RNA elimination and RAGE kinetics distinguish COVID‐19 severity

por Deng, Xiaoyan, Gantner, Pierre, Forestell, Julia, Pagliuzza, Amélie, Brunet‐Ratnasingham, Elsa, Durand, Madeleine, Kaufmann, Daniel E, Chomont, Nicolas, Craig, Morgan
Publicado 2023

Interplay between the Lung Microbiome, Pulmonary Immunity and Viral Reservoirs in People Living with HIV under Antiretroviral Therapy

por Wang, Zihui, Jenabian, Mohammad-Ali, Alexandrova, Yulia, Pagliuzza, Amélie, Olivenstein, Ron, Samarani, Suzanne, Chomont, Nicolas, Kembel, Steven W., Costiniuk, Cecilia T.
Publicado 2022

Increasing procaspase 8 expression using repurposed drugs to induce HIV infected cell death in ex vivo patient cells

por Sampath, Rahul, Cummins, Nathan W., Natesampillai, Sekar, Bren, Gary D., Chung, Thomas D., Baker, Jason, Henry, Keith, Pagliuzza, Amélie, Badley, Andrew D.
Publicado 2017

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

por Pardons, Marion, Baxter, Amy E., Massanella, Marta, Pagliuzza, Amélie, Fromentin, Rémi, Dufour, Caroline, Leyre, Louise, Routy, Jean-Pierre, Kaufmann, Daniel E., Chomont, Nicolas
Publicado 2019

Long-term effects of early antiretroviral initiation on HIV reservoir markers: a longitudinal analysis of the MERLIN clinical study

por Massanella, Marta, Ignacio, Rachel A Bender, Lama, Javier R, Pagliuzza, Amélie, Dasgupta, Sayan, Alfaro, Ricardo, Rios, Jessica, Ganoza, Carmela, Pinto-Santini, Delia, Gilada, Trupti, Duerr, Ann, Chomont, Nicolas
Publicado 2021

HIV persistence in mucosal CD4(+) T cells within the lungs of adults receiving long-term suppressive antiretroviral therapy

por Costiniuk, Cecilia T., Salahuddin, Syim, Farnos, Omar, Olivenstein, Ron, Pagliuzza, Amélie, Orlova, Marianna, Schurr, Erwin, De Castro, Christina, Bourbeau, Jean, Routy, Jean-Pierre, Ancuta, Petronela, Chomont, Nicolas, Jenabian, Mohammad-Ali
Publicado 2018

Preferential Infection of α4β7(+) Memory CD4(+) T Cells During Early Acute Human Immunodeficiency Virus Type 1 Infection

por Tokarev, Andrey, McKinnon, Lyle R, Pagliuzza, Amélie, Sivro, Aida, Omole, Tosin E, Kroon, Eugene, Chomchey, Nitiya, Phanuphak, Nittaya, Schuetz, Alexandra, Robb, Merlin L, Eller, Michael A, Ananworanich, Jintanat, Chomont, Nicolas, Bolton, Diane L
Publicado 2020

Potential for Virus Endogenization in Humans through Testicular Germ Cell Infection: the Case of HIV

por Mahé, Dominique, Matusali, Giulia, Deleage, Claire, Alvarenga, Raquel L. L. S., Satie, Anne-Pascale, Pagliuzza, Amélie, Mathieu, Romain, Lavoué, Sylvain, Jégou, Bernard, de França, Luiz R., Chomont, Nicolas, Houzet, Laurent, Rolland, Antoine D., Dejucq-Rainsford, Nathalie
Publicado 2020

HIV Infection and Persistence in Pulmonary Mucosal Double Negative T Cells In Vivo

por Meziane, Oussama, Salahuddin, Syim, Pham, Tram N. Q., Farnos, Omar, Pagliuzza, Amélie, Olivenstein, Ron, Thomson, Elaine, Alexandrova, Yulia, Orlova, Marianna, Schurr, Erwin, Ancuta, Petronela, Haddad, Élie, Chomont, Nicolas, Cohen, Eric A., Jenabian, Mohammad-Ali, Costiniuk, Cecilia T.
Publicado 2020

LILAC pilot study: Effects of metformin on mTOR activation and HIV reservoir persistence during antiretroviral therapy

por Planas, Delphine, Pagliuzza, Amélie, Ponte, Rosalie, Fert, Augustine, Marchand, Laurence Raymond, Massanella, Marta, Gosselin, Annie, Mehraj, Vikram, Dupuy, Franck P, Isnard, Stéphane, Goulet, Jean-Philippe, Lesage, Sylvie, Cohen, Eric A., Ghali, Mager Peter, Angel, Jonathan B., Chomont, Nicolas, Routy, Jean-Pierre, Ancuta, Petronela
Publicado 2021

Effects of Oral Cannabinoids on Systemic Inflammation and Viral Reservoir Markers in People with HIV on Antiretroviral Therapy: Results of the CTN PT028 Pilot Clinical Trial

por Mboumba Bouassa, Ralph-Sydney, Comeau, Eve, Alexandrova, Yulia, Pagliuzza, Amélie, Yero, Alexis, Samarani, Suzanne, Needham, Judy, Singer, Joel, Lee, Terry, Bobeuf, Florian, Vertzagias, Claude, Sebastiani, Giada, Margolese, Shari, Mandarino, Enrico, Klein, Marina B., Lebouché, Bertrand, Routy, Jean-Pierre, Chomont, Nicolas, Costiniuk, Cecilia T., Jenabian, Mohammad-Ali
Publicado 2023

Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size

por Stone, Mars, Rosenbloom, Daniel I S, Bacchetti, Peter, Deng, Xutao, Dimapasoc, Melanie, Keating, Sheila, Bakkour, Sonia, Richman, Douglas D, Mellors, John W, Deeks, Steven G, Lai, Jun, Beg, Subul, Siliciano, Janet D, Pagliuzza, Amélie, Chomont, Nicolas, Lackman-Smith, Carol, Ptak, Roger G, Busch, Michael P
Publicado 2020

An active HIV reservoir during ART is associated with maintenance of HIV-specific CD8(+) T cell magnitude and short-lived differentiation status

por Takata, Hiroshi, Mitchell, Julie L., Pacheco, Julian, Pagliuzza, Amélie, Pinyakorn, Suteeraporn, Buranapraditkun, Supranee, Sacdalan, Carlo, Leyre, Louise, Nathanson, Sam, Kakazu, Juyeon C., Intasan, Jintana, Prueksakaew, Peeriya, Chomchey, Nitiya, Phanuphak, Nittaya, de Souza, Mark, Haddad, Elias K., Rolland, Morgane, Tovanabutra, Sodsai, Vasan, Sandhya, Hsu, Denise C., Chomont, Nicolas, Trautmann, Lydie
Publicado 2023

Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART

por Pino, Maria, Pereira Ribeiro, Susan, Pagliuzza, Amélie, Ghneim, Khader, Khan, Anum, Ryan, Emily, Harper, Justin L., King, Colin T., Welbourn, Sarah, Micci, Luca, Aldrete, Sol, Delman, Keith A., Stuart, Theron, Lowe, Michael, Brenchley, Jason M., Derdeyn, Cynthia A., Easley, Kirk, Sekaly, Rafick P., Chomont, Nicolas, Paiardini, Mirko, Marconi, Vincent C.
Publicado 2021

Limited impact of fingolimod treatment during the initial weeks of ART in SIV-infected rhesus macaques

por Pino, Maria, Pagliuzza, Amélie, Pampena, M. Betina, Deleage, Claire, Viox, Elise G., Nguyen, Kevin, Shim, Inbo, Zhang, Adam, Harper, Justin L., Samer, Sadia, King, Colin T., Cervasi, Barbara, Gill, Kiran P., Ehnert, Stephanie, Jean, Sherrie M., Freeman, Michael L., Lifson, Jeffrey D., Kulpa, Deanna, Betts, Michael R., Chomont, Nicolas, Lederman, Michael M., Paiardini, Mirko
Publicado 2022

Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection

por Colby, Donn, Trautmann, Lydie, Pinyakorn, Suteeraporn, Leyre, Louise, Pagliuzza, Amelie, Kroon, Eugène, Rolland, Morgane, Takata, Hiroshi, Buranapraditkun, Supranee, Intasan, Jintana, Chomchey, Nitiya, Muir, Roshell, Haddad, Elias K., Tovanabutra, Sodsai, Ubolyam, Sasiwimol, Bolton, Diane L., Fullmer, Brandie A., Gorelick, Robert, Fox, Lawrence, Crowell, Trevor, Trichavaroj, Rapee, O’Connell, Robert, Chomont, Nicolas, Kim, Jerome H., Michael, Nelson L., Robb, Merlin L., Phanuphak, Nittaya, Ananworanich, Jintanat
Publicado 2018

Preferential and persistent impact of acute HIV-1 infection on CD4(+) iNKT cells in colonic mucosa

por Paquin-Proulx, Dominic, Lal, Kerri G., Phuang-Ngern, Yuwadee, Creegan, Matthew, Tokarev, Andrey, Suhkumvittaya, Suchada, Alrubayyi, Aljawharah, Kroon, Eugène, Pinyakorn, Suteeraporn, Slike, Bonnie M., Bolton, Diane L., Krebs, Shelly J., Eller, Leigh Anne, Sajjaweerawan, Chayada, Pagliuzza, Amélie, Chomont, Nicolas, Rerknimitr, Rungsun, Chomchey, Nitiya, Phanuphak, Nittaya, de Souza, Mark S., Michael, Nelson L., Robb, Merlin L., Ananworanich, Jintanat, Sandberg, Johan K., Eller, Michael A., Schuetz, Alexandra
Publicado 2021

A randomized trial of vorinostat with treatment interruption after initiating antiretroviral therapy during acute HIV-1 infection

por Kroon, Eugène D.M.B., Ananworanich, Jintanat, Pagliuzza, Amélie, Rhodes, Ajantha, Phanuphak, Nittaya, Trautmann, Lydie, Mitchell, Julie L., Chintanaphol, Michelle, Intasan, Jintana, Pinyakorn, Suteeraporn, Benjapornpong, Khuntalee, Chang, J. Judy, Colby, Donn J., Chomchey, Nitiya, Fletcher, James L.K., Eubanks, Keith, Yang, Hua, Kapson, John, Dantanarayana, Ashanti, Tennakoon, Surekha, Gorelick, Robert J., Maldarelli, Frank, Robb, Merlin L., Kim, Jerome H., Spudich, Serena, Chomont, Nicolas, Phanuphak, Praphan, Lewin, Sharon R., de Souza, Mark S.
Publicado 2020

Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound

por Cale, Evan M., Bai, Hongjun, Bose, Meera, Messina, Michael A., Colby, Donn J., Sanders-Buell, Eric, Dearlove, Bethany, Li, Yifan, Engeman, Emily, Silas, Daniel, O’Sullivan, Anne Marie, Mann, Brendan, Pinyakorn, Suteeraporn, Intasan, Jintana, Benjapornpong, Khunthalee, Sacdalan, Carlo, Kroon, Eugène, Phanuphak, Nittaya, Gramzinski, Robert, Vasan, Sandhya, Robb, Merlin L., Michael, Nelson L., Lynch, Rebecca M., Bailer, Robert T., Pagliuzza, Amélie, Chomont, Nicolas, Pegu, Amarendra, Doria-Rose, Nicole A., Trautmann, Lydie, Crowell, Trevor A., Mascola, John R., Ananworanich, Jintanat, Tovanabutra, Sodsai, Rolland, Morgane
Publicado 2020