Machine Learning-Supported Analyses Improve Quantitative Histological Assessments of Amyloid-β Deposits and Activated Microglia

por Bascuñana, Pablo, Brackhan, Mirjam, Pahnke, Jens
Publicado 2021

Role of ABCA7 in Human Health and in Alzheimer’s Disease

por Dib, Shiraz, Pahnke, Jens, Gosselet, Fabien
Publicado 2021

HD_BPMDS: a curated binary pattern multitarget dataset of Huntington’s disease–targeting agents

por Stefan, Sven Marcel, Pahnke, Jens, Namasivayam, Vigneshwaran
Publicado 2023

Early Cognitive Training Rescues Remote Spatial Memory but Reduces Cognitive Flexibility in Alzheimer’s Disease Mice

por Rai, Surya Prakash, Krohn, Markus, Pahnke, Jens
Publicado 2020

Fingolimod as a Treatment in Neurologic Disorders Beyond Multiple Sclerosis

por Bascuñana, Pablo, Möhle, Luisa, Brackhan, Mirjam, Pahnke, Jens
Publicado 2020

Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics

por Namasivayam, Vigneshwaran, Stefan, Katja, Pahnke, Jens, Stefan, Sven Marcel
Publicado 2021

A curated binary pattern multitarget dataset of focused ATP-binding cassette transporter inhibitors

por Stefan, Sven Marcel, Jansson, Patric Jan, Pahnke, Jens, Namasivayam, Vigneshwaran
Publicado 2022

C@PA: Computer-Aided Pattern Analysis to Predict Multitarget ABC Transporter Inhibitors

por Namasivayam, Vigneshwaran, Silbermann, Katja, Wiese, Michael, Pahnke, Jens, Stefan, Sven Marcel
Publicado 2021

Scaffold fragmentation and substructure hopping reveal potential, robustness, and limits of computer-aided pattern analysis (C@PA)

por Namasivayam, Vigneshwaran, Silbermann, Katja, Pahnke, Jens, Wiese, Michael, Stefan, Sven Marcel
Publicado 2021

In vivo (1)H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment

por Westman, Eric, Spenger, Christian, Öberg, Johanna, Reyer, Henry, Pahnke, Jens, Wahlund, Lars-Olof
Publicado 2009

Structural feature-driven pattern analysis for multitarget modulator landscapes

por Namasivayam, Vigneshwaran, Stefan, Katja, Silbermann, Katja, Pahnke, Jens, Wiese, Michael, Stefan, Sven Marcel
Publicado 2021

Functionally Relevant Domains of the Prion Protein Identified In Vivo

por Baumann, Frank, Pahnke, Jens, Radovanovic, Ivan, Rülicke, Thomas, Bremer, Juliane, Tolnay, Markus, Aguzzi, Adriano
Publicado 2009

Sideritis spp. Extracts Enhance Memory and Learning in Alzheimer’s β-Amyloidosis Mouse Models and Aged C57Bl/6 Mice

por Hofrichter, Jacqueline, Krohn, Markus, Schumacher, Toni, Lange, Cathleen, Feistel, Bjöorn, Walbroel, Bernd, Pahnke, Jens
Publicado 2016

A New Tool for the Analysis of the Effect of Intracerebrally Injected Anti-Amyloid-β Compounds

por Upīte, Jolanta, Brüning, Thomas, Möhle, Luisa, Brackhan, Mirjam, Bascuñana, Pablo, Jansone, Baiba, Pahnke, Jens
Publicado 2021

Indole Derivatives as New Structural Class of Potent and Antiproliferative Inhibitors of Monocarboxylate Transporter 1 (MCT1; SLC16A1)

por Puri, Sachin, Stefan, Katja, Khan, Sharuk L., Pahnke, Jens, Stefan, Sven Marcel, Juvale, Kapil
Publicado 2022

Detection and Prediction of Mild Cognitive Impairment in Alzheimer’s Disease Mice

por Rai, Surya Prakash, Bascuñana, Pablo, Brackhan, Mirjam, Krohn, Markus, Möhle, Luisa, Paarmann, Kristin, Pahnke, Jens
Publicado 2020

A novel sialyl Le(X) expression score as a potential prognostic tool in colorectal cancer

por Schiffmann, Leif, Schwarz, Fabian, Linnebacher, Michael, Prall, Friedrich, Pahnke, Jens, Krentz, Helga, Vollmar, Brigitte, Klar, Ernst
Publicado 2012

Time- and Sex-Dependent Effects of Fingolimod Treatment in a Mouse Model of Alzheimer’s Disease

por Bascuñana, Pablo, Brackhan, Mirjam, Möhle, Luisa, Wu, Jingyun, Brüning, Thomas, Eiriz, Ivan, Jansone, Baiba, Pahnke, Jens
Publicado 2023

Humanization of the Blood–Brain Barrier Transporter ABCB1 in Mice Disrupts Genomic Locus — Lessons from Three Unsuccessful Approaches

por Krohn, Markus, Wanek, Thomas, Menet, Marie-Claude, Noack, Andreas, Declèves, Xavier, Langer, Oliver, Löscher, Wolfgang, Pahnke, Jens
Publicado 2018

A Novel Huntington’s Disease Assessment Platform to Support Future Drug Discovery and Development

por Wu, Jingyun, Möhle, Luisa, Brüning, Thomas, Eiriz, Iván, Rafehi, Muhammad, Stefan, Katja, Stefan, Sven Marcel, Pahnke, Jens
Publicado 2022