Tubular aggregates caused by serine active site containing 1 (SERAC1) mutations in a patient with a mitochondrial encephalopathy

por Wedatilake, Yehani, Plagnol, Vincent, Anderson, Glenn, Paine, Simon M. L., Clayton, Peter T., Jacques, Thomas S., Rahman, Shamima
Publicado 2015

Pale Body-Like Inclusion Formation and Neurodegeneration following Depletion of 26S Proteasomes in Mouse Brain Neurones are Independent of α-Synuclein

por Paine, Simon M. L., Anderson, Glenn, Bedford, Karen, Lawler, Karen, Mayer, R. John, Lowe, James, Bedford, Lynn
Publicado 2013

Untargeted Metabolomic Characterization of Glioblastoma Intra-Tumor Heterogeneity Using OrbiSIMS

por He, Wenshi, Edney, Max K., Paine, Simon M. L., Griffiths, Rian L., Scurr, David J., Rahman, Ruman, Kim, Dong-Hyun
Publicado 2023

Challenges for the functional diffusion map in pediatric brain tumors

por Grech-Sollars, Matthew, Saunders, Dawn E., Phipps, Kim P., Kaur, Ramneek, Paine, Simon M.L., Jacques, Thomas S., Clayden, Jonathan D., Clark, Chris A.
Publicado 2014

Spatially resolved transcriptomic profiles reveal unique defining molecular features of infiltrative 5ALA-metabolizing cells associated with glioblastoma recurrence

por Andrieux, Geoffroy, Das, Tonmoy, Griffin, Michaela, Straehle, Jakob, Paine, Simon M. L., Beck, Jürgen, Boerries, Melanie, Heiland, Dieter H., Smith, Stuart J., Rahman, Ruman, Chakraborty, Sajib
Publicado 2023

Neuropathology of neurocutaneous melanosis: histological foci of melanotic neurones and glia may be undetectable on MRI

por Kinsler, Veronica A., Paine, Simon M. L., Anderson, Glenn W., Wijesekara, D. Saraji, Sebire, Neil J., Chong, Wui K., Harkness, William, Aylett, Sarah E., Jacques, Thomas S.
Publicado 2012

Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway

por Ugun-Klusek, Aslihan, Tatham, Michael H, Elkharaz, Jamal, Constantin-Teodosiu, Dumitru, Lawler, Karen, Mohamed, Hala, Paine, Simon M L, Anderson, Glen, John Mayer, R, Lowe, James, Ellen Billett, E, Bedford, Lynn
Publicado 2017

Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours

por Bennett, Christopher D., Kohe, Sarah E., Gill, Simrandip K., Davies, Nigel P., Wilson, Martin, Storer, Lisa C. D., Ritzmann, Timothy, Paine, Simon M. L., Scott, Ian S., Nicklaus-Wollenteit, Ina, Tennant, Daniel A., Grundy, Richard G., Peet, Andrew C.
Publicado 2018

Multi-omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high-risk pediatric ependymoma

por Griesinger, Andrea M., Riemondy, Kent, Eswaran, Nithyashri, Donson, Andrew M., Willard, Nicholas, Prince, Eric W., Paine, Simon M.L., Bowes, Georgia, Rheaume, John, Chapman, Rebecca J., Ramage, Judith, Jackson, Andrew, Grundy, Richard G., Foreman, Nicholas K., Ritzmann, Timothy A.
Publicado 2023

Astrovirus VA1/HMO-C: An Increasingly Recognized Neurotropic Pathogen in Immunocompromised Patients

por Brown, Julianne R., Morfopoulou, Sofia, Hubb, Jonathan, Emmett, Warren A., Ip, Winnie, Shah, Divya, Brooks, Tony, Paine, Simon M. L., Anderson, Glenn, Virasami, Alex, Tong, C. Y. William, Clark, Duncan A., Plagnol, Vincent, Jacques, Thomas S., Qasim, Waseem, Hubank, Mike, Breuer, Judith
Publicado 2015

EPEN-04. SIOP EPENDYMOMA I: FINAL RESULTS, LONG TERM FOLLOW-UP AND MOLECULAR ANALYSIS OF THE TRIAL COHORT: A BIOMECA CONSORTIUM STUDY

por A. Ritzmann, Timothy, Chapman, Rebecca J, Macarthur, Donald, Mallucci, Conor, Kilday, John-Paul, Thorp, Nicola, Modena, Piergiorgio, Giagnacovo, Marzia, Dineen, Rob, Jaspan, Timothy, Pajtler, Kristian W, Jacques, Thomas S, Paine, Simon M L, Ellison, David W, Bouffet, Eric, Grundy, Richard G
Publicado 2021

SIOP Ependymoma I: Final results, long-term follow-up, and molecular analysis of the trial cohort—A BIOMECA Consortium Study

por Ritzmann, Timothy A, Chapman, Rebecca J, Kilday, John-Paul, Thorp, Nicola, Modena, Piergiorgio, Dineen, Robert A, Macarthur, Donald, Mallucci, Conor, Jaspan, Timothy, Pajtler, Kristian W, Giagnacovo, Marzia, Jacques, Thomas S, Paine, Simon M L, Ellison, David W, Bouffet, Eric, Grundy, Richard G
Publicado 2022

EPEN-24. Biological markers of ependymoma in children and adolescents (BIOMECA): Systematic comparison of methods for the precise evaluation of biomarkers for ependymoma diagnosis...

por Chapman, Rebecca, Ghasemi, David R, LeBlond, Pierre, Witt, Hendrik, Grill, Jacques, Kilday, John-Paul, Modena, Piergiorgio, Varlet, Pascale, Tauziede-Espariat, Arnault, Haberler, Christine, Buttarelli, Francesca, Giangaspero, Felice, Paine, Simon M L, Jacques, Thomas S, Scott, Ian, Andreiuolo, Felipe, Pietsch, Torsten, Massimino, Maura, Grundy, Richard, Pajtler, Kristian W, Ritzmann, Timothy A
Publicado 2022

EPEN-02. OPTIMISING BIOMARKERS FOR ACCURATE EPENDYMOMA DIAGNOSIS, PROGNOSTICATION AND STRATIFICATION WITHIN INTERNATIONAL CLINICAL TRIALS: A BIOMECA STUDY

por Chapman, Rebecca J, Ghasemi, David R, Andreiuolo, Felipe, Zschernack, Valentina, Espariat, Arnault Tauziede, Buttarelli, Francesca, Giangaspero, Felice, Grill, Jacques, Haberler, Christine, Paine, Simon M L, Scott, Ian, Jacques, Thomas S, Sill, Martin, Stephan, Pfister, Kilday, John Paul, LeBlond, Pierre, Massimino, Maura, Modena, Piergiorgio, Varlet, Pascale, Pietsch, Torsten, Grundy, Richard G, Pajtler, Kristian W, Ritzmann, Timothy A
Publicado 2023

Optimizing biomarkers for accurate ependymoma diagnosis, prognostication, and stratification within International Clinical Trials: A BIOMECA study

por Chapman, Rebecca J, Ghasemi, David R, Andreiuolo, Felipe, Zschernack, Valentina, Espariat, Arnault Tauziede, Buttarelli, Francesca R, Giangaspero, Felice, Grill, Jacques, Haberler, Christine, Paine, Simon M L, Scott, Ian, Jacques, Thomas S, Sill, Martin, Pfister, Stefan, Kilday, John-Paul, Leblond, Pierre, Massimino, Maura, Witt, Hendrik, Modena, Piergiorgio, Varlet, Pascale, Pietsch, Torsten, Grundy, Richard G, Pajtler, Kristian W, Ritzmann, Timothy A
Publicado 2023