Fast estimation of genetic correlation for biobank-scale data

por Wu, Yue, Burch, Kathryn S., Ganna, Andrea, Pajukanta, Päivi, Pasaniuc, Bogdan, Sankararaman, Sriram
Publicado 2022

Reverse GWAS: Using genetics to identify and model phenotypic subtypes

por Dahl, Andy, Cai, Na, Ko, Arthur, Laakso, Markku, Pajukanta, Päivi, Flint, Jonathan, Zaitlen, Noah
Publicado 2019

Merging microsatellite data: enhanced methodology and software to combine genotype data for linkage and association analysis

por Presson, Angela P, Sobel, Eric M, Pajukanta, Paivi, Plaisier, Christopher, Weeks, Daniel E, Åberg, Karolina, Papp, Jeanette C
Publicado 2008

Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis

por Garske, Kristina M., Comenho, Caroline, Pan, David Z., Alvarez, Marcus, Mohlke, Karen, Laakso, Markku, Pietiläinen, Kirsi H., Pajukanta, Päivi
Publicado 2022

Identification of 90 NAFLD GWAS loci and establishment of NAFLD PRS and causal role of NAFLD in coronary artery disease

por Miao, Zong, Garske, Kristina M., Pan, David Z., Koka, Amogha, Kaminska, Dorota, Männistö, Ville, Sinsheimer, Janet S., Pihlajamäki, Jussi, Pajukanta, Päivi
Publicado 2021

A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context

por Gallois, Apolline, Mefford, Joel, Ko, Arthur, Vaysse, Amaury, Julienne, Hanna, Ala-Korpela, Mika, Laakso, Markku, Zaitlen, Noah, Pajukanta, Päivi, Aschard, Hugues
Publicado 2019

A Systems Genetics Approach Implicates USF1, FADS3, and Other Causal Candidate Genes for Familial Combined Hyperlipidemia

por Plaisier, Christopher L., Horvath, Steve, Huertas-Vazquez, Adriana, Cruz-Bautista, Ivette, Herrera, Miguel F., Tusie-Luna, Teresa, Aguilar-Salinas, Carlos, Pajukanta, Päivi
Publicado 2009

Accurate estimation of cell composition in bulk expression through robust integration of single-cell information

por Jew, Brandon, Alvarez, Marcus, Rahmani, Elior, Miao, Zong, Ko, Arthur, Garske, Kristina M., Sul, Jae Hoon, Pietiläinen, Kirsi H., Pajukanta, Päivi, Halperin, Eran
Publicado 2020

Publisher Correction: Accurate estimation of cell composition in bulk expression through robust integration of single-cell information

por Jew, Brandon, Alvarez, Marcus, Rahmani, Elior, Miao, Zong, Ko, Arthur, Garske, Kristina M., Sul, Jae Hoon, Pietiläinen, Kirsi H., Pajukanta, Päivi, Halperin, Eran
Publicado 2020

Protein Phosphatase 1 Regulatory Subunit 3B Genotype at rs4240624 Has a Major Effect on Gallbladder Bile Composition

por Männistö, Ville, Kaminska, Dorota, Käkelä, Pirjo, Neuvonen, Mikko, Niemi, Mikko, Alvarez, Marcus, Pajukanta, Päivi, Romeo, Stefano, Nieuwdorp, Max, Groen, Albert.K., Pihlajamäki, Jussi
Publicado 2020

Human liver single nucleus and single cell RNA sequencing identify a hepatocellular carcinoma-associated cell-type affecting survival

por Alvarez, Marcus, Benhammou, Jihane N., Darci-Maher, Nicholas, French, Samuel W., Han, Steven B., Sinsheimer, Janet S., Agopian, Vatche G., Pisegna, Joseph R., Pajukanta, Päivi
Publicado 2022

Serum aromatic and branched‐chain amino acids associated with NASH demonstrate divergent associations with serum lipids

por de Mello, Vanessa D., Sehgal, Ratika, Männistö, Ville, Klåvus, Anton, Nilsson, Emma, Perfilyev, Alexander, Kaminska, Dorota, Miao, Zong, Pajukanta, Päivi, Ling, Charlotte, Hanhineva, Kati, Pihlajamäki, Jussi
Publicado 2020

Indole-3-Propionic Acid, a Gut-Derived Tryptophan Metabolite, Associates with Hepatic Fibrosis

por Sehgal, Ratika, Ilha, Mariana, Vaittinen, Maija, Kaminska, Dorota, Männistö, Ville, Kärjä, Vesa, Tuomainen, Marjo, Hanhineva, Kati, Romeo, Stefano, Pajukanta, Päivi, Pihlajamäki, Jussi, de Mello, Vanessa D.
Publicado 2021

Enhancing droplet-based single-nucleus RNA-seq resolution using the semi-supervised machine learning classifier DIEM

por Alvarez, Marcus, Rahmani, Elior, Jew, Brandon, Garske, Kristina M., Miao, Zong, Benhammou, Jihane N., Ye, Chun Jimmie, Pisegna, Joseph R., Pietiläinen, Kirsi H., Halperin, Eran, Pajukanta, Päivi
Publicado 2020

Risk Alleles of USF1 Gene Predict Cardiovascular Disease of Women in Two Prospective Studies

por Komulainen, Kati, Alanne, Mervi, Auro, Kirsi, Kilpikari, Riika, Pajukanta, Päivi, Saarela, Janna, Ellonen, Pekka, Salminen, Kaisa, Kulathinal, Sangita, Kuulasmaa, Kari, Silander, Kaisa, Salomaa, Veikko, Perola, Markus, Peltonen, Leena
Publicado 2006

Genetic and environmental perturbations lead to regulatory decoherence

por Lea, Amanda, Subramaniam, Meena, Ko, Arthur, Lehtimäki, Terho, Raitoharju, Emma, Kähönen, Mika, Seppälä, Ilkka, Mononen, Nina, Raitakari, Olli T, Ala-Korpela, Mika, Pajukanta, Päivi, Zaitlen, Noah, Ayroles, Julien F
Publicado 2019

Novel Lipid Long Intervening Noncoding RNA, Oligodendrocyte Maturation‐Associated Long Intergenic Noncoding RNA, Regulates the Liver Steatosis Gene Stearoyl‐Coenzyme A Desaturase A...

por Benhammou, Jihane N., Ko, Arthur, Alvarez, Marcus, Kaikkonen, Minna U., Rankin, Carl, Garske, Kristina M., Padua, David, Bhagat, Yash, Kaminska, Dorota, Kärjä, Vesa, Pihlajamäki, Jussi, Pisegna, Joseph R., Pajukanta, Päivi
Publicado 2019

Increased body mass index is linked to systemic inflammation through altered chromatin co-accessibility in human preadipocytes

por Garske, Kristina M., Kar, Asha, Comenho, Caroline, Balliu, Brunilda, Pan, David Z., Bhagat, Yash V., Rosenberg, Gregory, Koka, Amogha, Das, Sankha Subhra, Miao, Zong, Sinsheimer, Janet S., Kaprio, Jaakko, Pietiläinen, Kirsi H., Pajukanta, Päivi
Publicado 2023

A nonsynonymous SNP within PCDH15 is associated with lipid traits in familial combined hyperlipidemia

por Huertas-Vazquez, Adriana, Plaisier, Christopher L., Geng, Ruishuang, Haas, Blake E., Lee, Jenny, Greevenbroek, Marleen M., van der Kallen, Carla, de Bruin, Tjerk W. A., Taskinen, Marja-Riitta, Alagramam, Kumar N., Pajukanta, Päivi
Publicado 2009

Role of Matrix Gla Protein in Transforming Growth Factor-β Signaling and Nonalcoholic Steatohepatitis in Mice

por Hui, Simon T., Gong, Lili, Swichkow, Chantle, Blencowe, Montgomery, Kaminska, Dorota, Diamante, Graciel, Pan, Calvin, Dalsania, Meet, French, Samuel W., Magyar, Clara E., Pajukanta, Päivi, Pihlajamäki, Jussi, Boström, Kristina I., Yang, Xia, Lusis, Aldons J.
Publicado 2023