Identity-by-Descent-Based Phasing and Imputation in Founder Populations Using Graphical Models

por Palin, Kimmo, Campbell, Harry, Wright, Alan F, Wilson, James F, Durbin, Richard
Publicado 2011

Transposable elements as tissue-specific enhancers in cancers of endodermal lineage

por Karttunen, Konsta, Patel, Divyesh, Xia, Jihan, Fei, Liangru, Palin, Kimmo, Aaltonen, Lauri, Sahu, Biswajyoti
Publicado 2023

Integrating sequence, evolution and functional genomics in regulatory genomics

por Vingron, Martin, Brazma, Alvis, Coulson, Richard, van Helden, Jacques, Manke, Thomas, Palin, Kimmo, Sand, Olivier, Ukkonen, Esko
Publicado 2009

Defining eligible patients for allele-selective chemotherapies targeting NAT2 in colorectal cancer

por Rendo, Veronica, Kundu, Snehangshu, Rameika, Natallia, Ljungström, Viktor, Svensson, Richard, Palin, Kimmo, Aaltonen, Lauri, Stoimenov, Ivaylo, Sjöblom, Tobias
Publicado 2020

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer

por Pitkänen, Esa, Cajuso, Tatiana, Katainen, Riku, Kaasinen, Eevi, Välimäki, Niko, Palin, Kimmo, Taipale, Jussi, Aaltonen, Lauri A., Kilpivaara, Outi
Publicado 2014

Vitamin C boosts DNA demethylation in TET2 germline mutation carriers

por Taira, Aurora, Palin, Kimmo, Kuosmanen, Anna, Välimäki, Niko, Kuittinen, Outi, Kuismin, Outi, Kaasinen, Eevi, Rajamäki, Kristiina, Aaltonen, Lauri A.
Publicado 2023

Detection of subclonal L1 transductions in colorectal cancer by long-distance inverse-PCR and Nanopore sequencing

por Pradhan, Barun, Cajuso, Tatiana, Katainen, Riku, Sulo, Päivi, Tanskanen, Tomas, Kilpivaara, Outi, Pitkänen, Esa, Aaltonen, Lauri A., Kauppi, Liisa, Palin, Kimmo
Publicado 2017

Human cell transformation by combined lineage conversion and oncogene expression

por Sahu, Biswajyoti, Pihlajamaa, Päivi, Zhang, Kaiyang, Palin, Kimmo, Ahonen, Saija, Cervera, Alejandra, Ristimäki, Ari, Aaltonen, Lauri A., Hautaniemi, Sampsa, Taipale, Jussi
Publicado 2021

Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

por Heinonen, Hanna-Riikka, Pasanen, Annukka, Heikinheimo, Oskari, Tanskanen, Tomas, Palin, Kimmo, Tolvanen, Jaana, Vahteristo, Pia, Sjöberg, Jari, Pitkänen, Esa, Bützow, Ralf, Mäkinen, Netta, Aaltonen, Lauri A.
Publicado 2017

Inherited mutations affecting the SRCAP complex are central in moderate-penetrance predisposition to uterine leiomyomas

por Välimäki, Niko, Jokinen, Vilja, Cajuso, Tatiana, Kuisma, Heli, Taira, Aurora, Dagnaud, Olivia, Ilves, Sini, Kaukomaa, Jaana, Pasanen, Annukka, Palin, Kimmo, Heikinheimo, Oskari, Bützow, Ralf, Aaltonen, Lauri A., Karhu, Auli
Publicado 2023

Molecular subclass of uterine fibroids predicts tumor shrinkage in response to ulipristal acetate

por Kolterud, Åsa, Välimäki, Niko, Kuisma, Heli, Patomo, Joonatan, Ilves, Sini T, Mäkinen, Netta, Kaukomaa, Jaana, Palin, Kimmo, Kaasinen, Eevi, Karhu, Auli, Pasanen, Annukka, Bützow, Ralf, Heikinheimo, Oskari, Kopp Kallner, Helena, Aaltonen, Lauri A
Publicado 2022

Exome-wide somatic mutation characterization of small bowel adenocarcinoma

por Hänninen, Ulrika A., Katainen, Riku, Tanskanen, Tomas, Plaketti, Roosa-Maria, Laine, Riku, Hamberg, Jiri, Ristimäki, Ari, Pukkala, Eero, Taipale, Minna, Mecklin, Jukka-Pekka, Forsström, Linda M., Pitkänen, Esa, Palin, Kimmo, Välimäki, Niko, Mäkinen, Netta, Aaltonen, Lauri A.
Publicado 2018

Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

por Välimäki, Niko, Kuisma, Heli, Pasanen, Annukka, Heikinheimo, Oskari, Sjöberg, Jari, Bützow, Ralf, Sarvilinna, Nanna, Heinonen, Hanna-Riikka, Tolvanen, Jaana, Bramante, Simona, Tanskanen, Tomas, Auvinen, Juha, Uimari, Outi, Alkodsi, Amjad, Lehtonen, Rainer, Kaasinen, Eevi, Palin, Kimmo, Aaltonen, Lauri A
Publicado 2018

Exome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers

por Hänninen, Ulrika A., Wirta, Erkki-Ville, Katainen, Riku, Tanskanen, Tomas, Hamberg, Jiri, Taipale, Minna, Böhm, Jan, Renkonen-Sinisalo, Laura, Lepistö, Anna, Forsström, Linda M., Pitkänen, Esa, Palin, Kimmo, Seppälä, Toni T., Mäkinen, Netta, Mecklin, Jukka-Pekka, Aaltonen, Lauri A.
Publicado 2019

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

por Wei, Gong-Hong, Badis, Gwenael, Berger, Michael F, Kivioja, Teemu, Palin, Kimmo, Enge, Martin, Bonke, Martin, Jolma, Arttu, Varjosalo, Markku, Gehrke, Andrew R, Yan, Jian, Talukder, Shaheynoor, Turunen, Mikko, Taipale, Mikko, Stunnenberg, Hendrik G, Ukkonen, Esko, Hughes, Timothy R, Bulyk, Martha L, Taipale, Jussi
Publicado 2010

Lack of an association between gallstone disease and bilirubin levels with risk of colorectal cancer: a Mendelian randomisation analysis

por Culliford, Richard, Cornish, Alex J., Law, Philip J., Farrington, Susan M., Palin, Kimmo, Jenkins, Mark A., Casey, Graham, Hoffmeister, Michael, Brenner, Hermann, Chang-Claude, Jenny, Kirac, Iva, Maughan, Tim, Brezina, Stefanie, Gsur, Andrea, Cheadle, Jeremy P., Aaltonen, Lauri A., Dunlop, Malcom G., Houlston, Richard S.
Publicado 2021

Parity associates with chromosomal damage in uterine leiomyomas

por Kuisma, Heli, Bramante, Simona, Rajamäki, Kristiina, Sipilä, Lauri J., Kaasinen, Eevi, Kaukomaa, Jaana, Palin, Kimmo, Mäkinen, Netta, Sjöberg, Jari, Sarvilinna, Nanna, Taipale, Jussi, Kauppi, Liisa, Tumiati, Manuela, Hassinen, Antti, Pitkäniemi, Janne, Jalkanen, Jyrki, Heikkinen, Sanna, Pasanen, Annukka, Heikinheimo, Oskari, Bützow, Ralf, Välimäki, Niko, Aaltonen, Lauri A.
Publicado 2021

Modifiable pathways for colorectal cancer: a mendelian randomisation analysis

por Cornish, Alex J, Law, Philip J, Timofeeva, Maria, Palin, Kimmo, Farrington, Susan M, Palles, Claire, Jenkins, Mark A, Casey, Graham, Brenner, Hermann, Chang-Claude, Jenny, Hoffmeister, Michael, Kirac, Iva, Maughan, Tim, Brezina, Stefanie, Gsur, Andrea, Cheadle, Jeremy P, Aaltonen, Lauri A, Tomlinson, Ian, Dunlop, Malcolm G, Houlston, Richard S
Publicado 2019

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

por Cajuso, Tatiana, Sulo, Päivi, Tanskanen, Tomas, Katainen, Riku, Taira, Aurora, Hänninen, Ulrika A., Kondelin, Johanna, Forsström, Linda, Välimäki, Niko, Aavikko, Mervi, Kaasinen, Eevi, Ristimäki, Ari, Koskensalo, Selja, Lepistö, Anna, Renkonen-Sinisalo, Laura, Seppälä, Toni, Kuopio, Teijo, Böhm, Jan, Mecklin, Jukka-Pekka, Kilpivaara, Outi, Pitkänen, Esa, Palin, Kimmo, Aaltonen, Lauri A.
Publicado 2019

MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors

por Brown, Rachel E., Jacobse, Justin, Anant, Shruti A., Blunt, Koral M., Chen, Bob, Vega, Paige N., Jones, Chase T., Pilat, Jennifer M., Revetta, Frank, Gorby, Aidan H., Stengel, Kristy R., Choksi, Yash A., Palin, Kimmo, Piazuelo, M. Blanca, Washington, Mary Kay, Lau, Ken S., Goettel, Jeremy A., Hiebert, Scott W., Short, Sarah P., Williams, Christopher S.
Publicado 2022