A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer

por Palit, Sander A. L., van Dorp, Jeroen, Vis, Daniel, Lieftink, Cor, Linder, Simon, Beijersbergen, Roderick, Bergman, Andries M., Zwart, Wilbert, van der Heijden, Michiel S.
Publicado 2021

TLE3 loss confers AR inhibitor resistance by facilitating GR-mediated human prostate cancer cell growth

por Palit, Sander AL, Vis, Daniel, Stelloo, Suzan, Lieftink, Cor, Prekovic, Stefan, Bekers, Elise, Hofland, Ingrid, Šuštić, Tonći, Wolters, Liesanne, Beijersbergen, Roderick, Bergman, Andries M, Győrffy, Balázs, Wessels, Lodewyk FA, Zwart, Wilbert, van der Heijden, Michiel S
Publicado 2019

Tumor suppressor BTG1 promotes PRMT1-mediated ATF4 function in response to cellular stress

por Yuniati, Laurensia, van der Meer, Laurens T., Tijchon, Esther, van Ingen Schenau, Dorette, van Emst, Liesbeth, Levers, Marloes, Palit, Sander A.L., Rodenbach, Caroline, Poelmans, Geert, Hoogerbrugge, Peter M., Shan, Jixiu, Kilberg, Michael S., Scheijen, Blanca, van Leeuwen, Frank N.
Publicado 2015

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma

por Vlaming, Hanneke, McLean, Chelsea M, Korthout, Tessy, Alemdehy, Mir Farshid, Hendriks, Sjoerd, Lancini, Cesare, Palit, Sander, Klarenbeek, Sjoerd, Kwesi‐Maliepaard, Eliza Mari, Molenaar, Thom M, Hoekman, Liesbeth, Schmidlin, Thierry T, Altelaar, AF Maarten, van Welsem, Tibor, Dannenberg, Jan‐Hermen, Jacobs, Heinz, van Leeuwen, Fred
Publicado 2019