Culling sick mitochondria from the herd

por Pallanck, Leo J.
Publicado 2010

Neurons at the extremes of cell biology

por Heiman, Maxwell G., Pallanck, Leo
Publicado 2011

Inactivation of Lon protease reveals a link between mitochondrial unfolded protein stress and mitochondrial translation inhibition

por Pareek, Gautam, Pallanck, Leo J.
Publicado 2018

Inactivation of the mitochondrial protease Afg3l2 results in severely diminished respiratory chain activity and widespread defects in mitochondrial gene expression

por Pareek, Gautam, Pallanck, Leo J.
Publicado 2020

Loss of the Drosophilam-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration

por Pareek, Gautam, Thomas, Ruth E., Pallanck, Leo J.
Publicado 2018

Tissue-restricted inhibition of mTOR using chemical genetics

por Wassarman, Douglas R., Bankapalli, Kondalarao, Pallanck, Leo J., Shokat, Kevan M.
Publicado 2022

The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway

por Poole, Angela C., Thomas, Ruth E., Yu, Selina, Vincow, Evelyn S., Pallanck, Leo
Publicado 2010

Lon protease inactivation in Drosophila causes unfolded protein stress and inhibition of mitochondrial translation

por Pareek, Gautam, Thomas, Ruth E., Vincow, Evelyn S., Morris, David R., Pallanck, Leo J.
Publicado 2018

PINK1-Parkin Pathway Activity Is Regulated by Degradation of PINK1 in the Mitochondrial Matrix

por Thomas, Ruth E., Andrews, Laurie A., Burman, Jonathon L., Lin, Wen-Yang, Pallanck, Leo J.
Publicado 2014

Glucocerebrosidase deficiency promotes protein aggregation through dysregulation of extracellular vesicles

por Thomas, Ruth E., Vincow, Evelyn S., Merrihew, Gennifer E., MacCoss, Michael J., Davis, Marie Y., Pallanck, Leo J.
Publicado 2018

Deleterious mitochondrial DNA point mutations are overrepresented in Drosophila expressing a proofreading-defective DNA polymerase γ

por Samstag, Colby L., Hoekstra, Jake G., Huang, Chiu-Hui, Chaisson, Mark J., Youle, Richard J., Kennedy, Scott R., Pallanck, Leo J.
Publicado 2018

Oxidative Stress Is Not a Major Contributor to Somatic Mitochondrial DNA Mutations

por Itsara, Leslie S., Kennedy, Scott R., Fox, Edward J., Yu, Selina, Hewitt, Joshua J., Sanchez-Contreras, Monica, Cardozo-Pelaez, Fernando, Pallanck, Leo J.
Publicado 2014

A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer

por Burman, Jonathon L., Itsara, Leslie S., Kayser, Ernst-Bernhard, Suthammarak, Wichit, Wang, Adrienne M., Kaeberlein, Matt, Sedensky, Margaret M., Morgan, Philip G., Pallanck, Leo J.
Publicado 2014

Glucocerebrosidase Deficiency in Drosophila Results in α-Synuclein-Independent Protein Aggregation and Neurodegeneration

por Davis, Marie Y., Trinh, Kien, Thomas, Ruth E., Yu, Selina, Germanos, Alexandre A., Whitley, Brittany N., Sardi, Sergio Pablo, Montine, Thomas J., Pallanck, Leo J.
Publicado 2016

A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster

por Patel, Maulik R, Miriyala, Ganesh K, Littleton, Aimee J, Yang, Heiko, Trinh, Kien, Young, Janet M, Kennedy, Scott R, Yamashita, Yukiko M, Pallanck, Leo J, Malik, Harmit S
Publicado 2016

Glucocerebrosidase reduces the spread of protein aggregation in a Drosophila melanogaster model of neurodegeneration by regulating proteins trafficked by extracellular vesicles

por Jewett, Kathryn A., Thomas, Ruth E., Phan, Chi Q., Lin, Bernice, Milstein, Gillian, Yu, Selina, Bettcher, Lisa F., Neto, Fausto Carnevale, Djukovic, Danijel, Raftery, Daniel, Pallanck, Leo J., Davis, Marie Y.
Publicado 2021

Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila

por Andreazza, Simonetta, Samstag, Colby L., Sanchez-Martinez, Alvaro, Fernandez-Vizarra, Erika, Gomez-Duran, Aurora, Lee, Juliette J., Tufi, Roberta, Hipp, Michael J., Schmidt, Elizabeth K., Nicholls, Thomas J., Gammage, Payam A., Chinnery, Patrick F., Minczuk, Michal, Pallanck, Leo J., Kennedy, Scott R., Whitworth, Alexander J.
Publicado 2019