Novel Insights Into the Etiology of Diabetes From Genome-Wide Association Studies

por Palmer, Colin N.A.
Publicado 2009

Ligand Modulated Antagonism of PPARγ by Genomic and Non-Genomic Actions of PPARδ

por Gustafsson, Mattias C. U., Knight, Deborah, Palmer, Colin N. A.
Publicado 2009

Activation of PPARβ/δ Causes a Psoriasis-Like Skin Disease In Vivo

por Romanowska, Malgorzata, Reilly, Louise, Palmer, Colin N. A., Gustafsson, Mattias C. U., Foerster, John
Publicado 2010

PPARα Is Required for PPARδ Action in Regulation of Body Weight and Hepatic Steatosis in Mice

por Garbacz, Wojciech G., Huang, Jeffrey T. J., Higgins, Larry G., Wahli, Walter, Palmer, Colin N. A.
Publicado 2015

Utility of Population-Level DNA Sequence Data in the Diagnosis of Hereditary Endocrine Disease

por Newey, Paul J., Berg, Jonathan N., Zhou, Kaixin, Palmer, Colin N.A., Thakker, Rajesh V.
Publicado 2017

Interaction between variants in the CYP2C9 and POR genes and the risk of sulfonylurea‐induced hypoglycaemia: A GoDARTS Study

por Dujic, Tanja, Zhou, Kaixin, Donnelly, Louise A., Leese, Graham, Palmer, Colin N. A., Pearson, Ewan R.
Publicado 2017

The association between SARS-CoV-2 RT-PCR cycle threshold and mortality in a community cohort

por Waudby-West, Rupert, Parcell, Benjamin J., Palmer, Colin N.A., Bell, Samira, Chalmers, James D., Siddiqui, Moneeza K.
Publicado 2021

Identification of 4 New Loci Associated With Primary Hyperparathyroidism (PHPT) and a Polygenic Risk Score for PHPT

por Soto-Pedre, Enrique, Newey, Paul J, Srinivasan, Sundararajan, Siddiqui, Moneeza K, Palmer, Colin N A, Leese, Graham P
Publicado 2022

Investigating Real‐World Clopidogrel Pharmacogenetics in Stroke Using a Bioresource Linked to Electronic Medical Records

por Tornio, Aleksi, Flynn, Rob, Morant, Steve, Velten, Elena, Palmer, Colin N. A., MacDonald, Thomas M., Doney, Alex S. F.
Publicado 2017

Genetic and pharmacological relationship between P-glycoprotein and increased cardiovascular risk associated with clarithromycin prescription: An epidemiological and genomic popula...

por Mordi, Ify R., Chan, Benjamin K., Yanez, N. David, Palmer, Colin N. A., Lang, Chim C., Chalmers, James D.
Publicado 2020

A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain

por Meng, Weihua, Deshmukh, Harshal A., Donnelly, Louise A., Torrance, Nicola, Colhoun, Helen M., Palmer, Colin N.A., Smith, Blair H.
Publicado 2015

Glycemic Exposure and Blood Pressure Influencing Progression and Remission of Diabetic Retinopathy: A longitudinal cohort study in GoDARTS

por Liu, Yiyuan, Wang, Minghui, Morris, Andrew D., Doney, Alex S.F., Leese, Graham P., Pearson, Ewan R., Palmer, Colin N.A.
Publicado 2013

A Genome-Wide Association Study Provides New Evidence That CACNA1C Gene is Associated With Diabetic Cataract

por Chang, Cheng, Zhang, Kaida, Veluchamy, Abirami, Hébert, Harry L., Looker, Helen C., Colhoun, Helen M., Palmer, Colin N. A., Meng, Weihua
Publicado 2016

PheGWAS: a new dimension to visualize GWAS across multiple phenotypes

por George, Gittu, Gan, Sushrima, Huang, Yu, Appleby, Philip, Nar, A S, Venkatesan, Radha, Mohan, Viswanathan, Palmer, Colin N A, Doney, Alex S F
Publicado 2020

Efficacy of Modern Diabetes Treatments DPP-4i, SGLT-2i, and GLP-1RA in White and Asian Patients With Diabetes: A Systematic Review and Meta-analysis of Randomized Controlled Trials

por Gan, Sushrima, Dawed, Adem Y., Donnelly, Louise A., Nair, Anand T.N., Palmer, Colin N.A., Mohan, Viswanathan, Pearson, Ewan R.
Publicado 2020

Response to Comment on Gan et al. Efficacy of Modern Diabetes Treatments DPP-4i, SGLT-2i, and GLP-1RA in White and Asian Patients With Diabetes: A Systematic Review and Meta-analys...

por Gan, Sushrima, Dawed, Adem Y., Donnelly, Louise A., Nair, Anand T.N., Palmer, Colin N.A., Mohan, Viswanathan, Pearson, Ewan R.
Publicado 2020

Type 2 Diabetes, Metabolic Traits, and Risk of Heart Failure: A Mendelian Randomization Study

por Mordi, Ify R., Lumbers, R. Thomas, Palmer, Colin N.A., Pearson, Ewan R., Sattar, Naveed, Holmes, Michael V., Lang, Chim C.
Publicado 2021

Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo

por Higgins, Larry G., Garbacz, Wojciech G., Gustafsson, Mattias C. U., Nainamalai, Sitheswaran, Ashby, Peter R., Wolf, C. Roland, Palmer, Colin N. A.
Publicado 2012

Assessing the Combined Impact of 18 Common Genetic Variants of Modest Effect Sizes on Type 2 Diabetes Risk

por Lango, Hana, Palmer, Colin N.A., Morris, Andrew D., Zeggini, Eleftheria, Hattersley, Andrew T., McCarthy, Mark I., Frayling, Timothy M., Weedon, Michael N.
Publicado 2008

Polymorphism in INSR Locus Modifies Risk of Atrial Fibrillation in Patients on Thyroid Hormone Replacement Therapy

por Soto-Pedre, Enrique, Siddiqui, Moneeza K., Maroteau, Cyrielle, Dawed, Adem Y., Doney, Alex S., Palmer, Colin N. A., Pearson, Ewan R., Leese, Graham P.
Publicado 2021