The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8(+) T cells

por Guittard, Geoffrey, Dios-Esponera, Ana, Palmer, Douglas C., Akpan, Itoro, Barr, Valarie A., Manna, Asit, Restifo, Nicholas P., Samelson, Lawrence E.
Publicado 2018

Viral Sequestration of Antigen Subverts Cross Presentation to CD8(+) T Cells

por Tewalt, Eric F., Grant, Jean M., Granger, Erica L., Palmer, Douglas C., Heuss, Neal D., Gregerson, Dale S., Restifo, Nicholas P., Norbury, Christopher C.
Publicado 2009

Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing

por Ji, Yun, Abrams, Natalie, Zhu, Wei, Salinas, Eddie, Yu, Zhiya, Palmer, Douglas C., Jailwala, Parthav, Franco, Zulmarie, Roychoudhuri, Rahul, Stahlberg, Eric, Gattinoni, Luca, Restifo, Nicholas P.
Publicado 2014

STING agonist promotes CAR T cell trafficking and persistence in breast cancer

por Xu, Nuo, Palmer, Douglas C., Robeson, Alexander C., Shou, Peishun, Bommiasamy, Hemamalini, Laurie, Sonia J., Willis, Caryn, Dotti, Gianpietro, Vincent, Benjamin G., Restifo, Nicholas P., Serody, Jonathan S.
Publicado 2020

Wnt signaling arrests effector T cell differentiation and generates CD8(+) memory stem cells

por Gattinoni, Luca, Zhong, Xiao-Song, Palmer, Douglas C, Ji, Yun, Hinrichs, Christian S, Yu, Zhiya, Wrzesinski, Claudia, Boni, Andrea, Cassard, Lydie, Church, Lindsay, Paulos, Chrystal M, Muranski, Pawel, Restifo, Nicholas P
Publicado 2009

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8(+) T cells

por Gattinoni, Luca, Finkelstein, Steven E., Klebanoff, Christopher A., Antony, Paul A., Palmer, Douglas C., Spiess, Paul J., Hwang, Leroy N., Yu, Zhiya, Wrzesinski, Claudia, Heimann, David M., Surh, Charles D., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado 2005

Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits CD8(+) T cell memory formation

por Ji, Yun, Pos, Zoltan, Rao, Mahadev, Klebanoff, Christopher A., Yu, Zhiya, Sukumar, Madhusudhanan, Reger, Robert N., Palmer, Douglas C., Borman, Zachary A., Muranski, Pawel, Wang, Ena, Schrump, David S., Marincola, Francesco M., Restifo, Nicholas P., Gattinoni, Luca
Publicado 2011

TSCOT (+) Thymic Epithelial Cell-Mediated Sensitive CD4 Tolerance by Direct Presentation

por Ahn, Sejin, Lee, Gwanghee, Yang, Soo Jung, Lee, Deokjae, Lee, Seunghyuk, Shin, Hyo Sun, Kim, Min Cheol, Lee, Kee Nyung, Palmer, Douglas C, Theoret, Marc R, Jenkinson, Eric J, Anderson, Graham, Restifo, Nicholas P, Kim, Moon Gyo
Publicado 2008

Lineage relationship of CD8(+) T cell subsets is revealed by progressive changes in the epigenetic landscape

por Crompton, Joseph G., Narayanan, Manikandan, Cuddapah, Suresh, Roychoudhuri, Rahul, Ji, Yun, Yang, Wenjing, Patel, Shashank J., Sukumar, Madhusudhanan, Palmer, Douglas C., Peng, Weiqun, Wang, Ena, Marincola, Francesco M., Klebanoff, Christopher A., Zhao, Keji, Tsang, John S., Gattinoni, Luca, Restifo, Nicholas P.
Publicado 2016

Ionic immune suppression within the tumour microenvironment limits T cell effector function

por Eil, Robert, Vodnala, Suman K, Clever, David, Klebanoff, Christopher A, Sukumar, Madhusudhanan, Pan, Jenny H, Palmer, Douglas C, Gros, Alena, Yamamoto, Tori N, Patel, Shashank J, Guittard, Geoffrey C, Yu, Zhiya, Carbonaro, Valentina, Okkenhaug, Klaus, Schrump, David S, Linehan, W Marston, Roychoudhuri, Rahul, Restifo, Nicholas P
Publicado 2016

Cish actively silences TCR signaling in CD8(+) T cells to maintain tumor tolerance

por Palmer, Douglas C., Guittard, Geoffrey C., Franco, Zulmarie, Crompton, Joseph G., Eil, Robert L., Patel, Shashank J., Ji, Yun, Van Panhuys, Nicholas, Klebanoff, Christopher A., Sukumar, Madhusudhanan, Clever, David, Chichura, Anna, Roychoudhuri, Rahul, Varma, Rajat, Wang, Ena, Gattinoni, Luca, Marincola, Francesco M., Balagopalan, Lakshmi, Samelson, Lawrence E., Restifo, Nicholas P.
Publicado 2015

Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8(+) T Cells

por Overwijk, Willem W., Theoret, Marc R., Finkelstein, Steven E., Surman, Deborah R., de Jong, Laurina A., Vyth-Dreese, Florry A., Dellemijn, Trees A., Antony, Paul A., Spiess, Paul J., Palmer, Douglas C., Heimann, David M., Klebanoff, Christopher A., Yu, Zhiya, Hwang, Leroy N., Feigenbaum, Lionel, Kruisbeek, Ada M., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado 2003

Retinoic acid controls the homeostasis of pre-cDC–derived splenic and intestinal dendritic cells

por Klebanoff, Christopher A., Spencer, Sean P., Torabi-Parizi, Parizad, Grainger, John R., Roychoudhuri, Rahul, Ji, Yun, Sukumar, Madhusudhanan, Muranski, Pawel, Scott, Christopher D., Hall, Jason A., Ferreyra, Gabriela A., Leonardi, Anthony J., Borman, Zachary A., Wang, Jinshan, Palmer, Douglas C., Wilhelm, Christoph, Cai, Rongman, Sun, Junfeng, Napoli, Joseph L., Danner, Robert L., Gattinoni, Luca, Belkaid, Yasmine, Restifo, Nicholas P.
Publicado 2013

Cancer genes disfavoring T cell immunity identified via integrated systems approach

por Kishton, Rigel J., Patel, Shashank J., Decker, Amy E., Vodnala, Suman K., Cam, Maggie, Yamamoto, Tori N., Patel, Yogin, Sukumar, Madhusudhanan, Yu, Zhiya, Ji, Michelle, Henning, Amanda N., Gurusamy, Devikala, Palmer, Douglas C., Stefanescu, Roxana A., Girvin, Andrew T., Lo, Winifred, Pasetto, Anna, Malekzadeh, Parisa, Deniger, Drew C., Wood, Kris C., Sanjana, Neville E., Restifo, Nicholas P.
Publicado 2022

BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers

por Roychoudhuri, Rahul, Clever, David, Li, Peng, Wakabayashi, Yoshiyuki, Quinn, Kylie M., Klebanoff, Christopher A., Ji, Yun, Sukumar, Madhusudhanan, Eil, Robert L., Yu, Zhiya, Spolski, Rosanne, Palmer, Douglas C., Pan, Jenny H., Patel, Shashank J., Macallan, Derek C, Fabozzi, Giulia, Shih, Han-Yu, Kanno, Yuka, Muto, Akihiko, Zhu, Jun, Gattinoni, Luca, O’Shea, John J., Okkenhaug, Klaus, Igarashi, Kazuhiko, Leonard, Warren J., Restifo, Nicholas P.
Publicado 2016