Age‐associated cholesterol reduction triggers brain insulin resistance by facilitating ligand‐independent receptor activation and pathway desensitization

por Martín‐Segura, Adrián, Ahmed, Tariq, Casadomé‐Perales, Álvaro, Palomares‐Perez, Irene, Palomer, Ernest, Kerstens, Axelle, Munck, Sebastian, Balschun, Detlef, Dotti, Carlos G.
Publicado 2019

Prodromal Alzheimer’s Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer’s Pathology

por de Vidania, Silvia, Palomares-Perez, Irene, Frank-García, Ana, Saito, Takashi, Saido, Takaomi C., Draffin, Jonathan, Szaruga, María, Chávez-Gutierrez, Lucía, Calero, Miguel, Medina, Miguel, Guix, Francesc X., Dotti, Carlos G.
Publicado 2020

Increased exosome secretion in neurons aging in vitro by NPC1-mediated endosomal cholesterol buildup

por Guix, Francesc X, Capitán, Ana Marrero, Casadomé-Perales, Álvaro, Palomares-Pérez, Irene, López del Castillo, Inés, Miguel, Verónica, Goedeke, Leigh, Martín, Mauricio G, Lamas, Santiago, Peinado, Héctor, Fernández-Hernando, Carlos, Dotti, Carlos G
Publicado 2021