Shedding Light on Filovirus Infection with High-Content Imaging

por Pegoraro, Gianluca, Bavari, Sina, Panchal, Rekha G.
Publicado 2012

Applications of In Vivo Imaging in the Evaluation of the Pathophysiology of Viral and Bacterial Infections and in Development of Countermeasures to BSL3/4 Pathogens

por Bocan, Thomas M., Panchal, Rekha G., Bavari, Sina
Publicado 2014

Bacterial genome engineering and synthetic biology: combating pathogens

por Krishnamurthy, Malathy, Moore, Richard T., Rajamani, Sathish, Panchal, Rekha G.
Publicado 2016

Screening of a Focused Ubiquitin-Proteasome Pathway Inhibitor Library Identifies Small Molecules as Novel Modulators of Botulinum Neurotoxin Type A Toxicity

por Sen, Edanur, Kota, Krishna P., Panchal, Rekha G., Bavari, Sina, Kiris, Erkan
Publicado 2021

Mitigating the Impact of Antibacterial Drug Resistance through Host-Directed Therapies: Current Progress, Outlook, and Challenges

por Chiang, Chih-Yuan, Uzoma, Ijeoma, Moore, Richard T., Gilbert, Merle, Duplantier, Allen J., Panchal, Rekha G.
Publicado 2018

Combating biothreat pathogens: ongoing efforts for countermeasure development and unique challenges

por Duplantier, Allen J., Shurtleff, Amy C., Miller, Cheryl, Chiang, Chih-Yuan, Panchal, Rekha G., Sunay, Melek
Publicado 2020

Biochip for the Detection of Bacillus anthracis Lethal Factor and Therapeutic Agents against Anthrax Toxins

por Silin, Vitalii, Kasianowicz, John J., Michelman-Ribeiro, Ariel, Panchal, Rekha G., Bavari, Sina, Robertson, Joseph W. F.
Publicado 2016

High Content Image Based Analysis Identifies Cell Cycle Inhibitors as Regulators of Ebola Virus Infection

por Kota, Krishna P., Benko, Jacqueline G., Mudhasani, Rajini, Retterer, Cary, Tran, Julie P., Bavari, Sina, Panchal, Rekha G.
Publicado 2012

A Limited Structural Modification Results in a Significantly More Efficacious Diazachrysene-Based Filovirus Inhibitor

por Selaković, Života, Opsenica, Dejan, Eaton, Brett, Retterer, Cary, Bavari, Sina, Burnett, James C., Šolaja, Bogdan A., Panchal, Rekha G.
Publicado 2012

Oncogene Amplification in Squamous Cell Carcinoma of the Oral Cavity

por Saranath, Dhananjaya, Panchal, Rekha G., Nair, Rama, Mehta, Ashok R., Sanghavi, Vikram, Sumegi, Janos, Klein, George, Deo, Madhav G.
Publicado 1989

Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections

por Iversen, Patrick L., Warren, Travis K., Wells, Jay B., Garza, Nicole L., Mourich, Dan V., Welch, Lisa S., Panchal, Rekha G., Bavari, Sina
Publicado 2012

A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages

por Pegoraro, Gianluca, Eaton, Brett P, Ulrich, Ricky L, Lane, Douglas J, Ojeda, Jenifer F, Bavari, Sina, DeShazer, David, Panchal, Rekha G
Publicado 2014

Heat fixation inactivates viral and bacterial pathogens and is compatible with downstream MALDI mass spectrometry tissue imaging

por Cazares, Lisa H, Van Tongeren, Sean A, Costantino, Julie, Kenny, Tara, Garza, Nicole L, Donnelly, Ginger, Lane, Douglas, Panchal, Rekha G, Bavari, Sina
Publicado 2015

Bioengineering of bacterial pathogens for noninvasive imaging and in vivo evaluation of therapeutics

por Rajamani, Sathish, Kuszpit, Kyle, Scarff, Jennifer M., Lundh, Linnea, Khan, Maisha, Brown, Jennifer, Stafford, Robert, Cazares, Lisa H., Panchal, Rekha G., Bocan, Thomas
Publicado 2018

Host response during Yersinia pestis infection of human bronchial epithelial cells involves negative regulation of autophagy and suggests a modulation of survival-related and cellu...

por Alem, Farhang, Yao, Kuan, Lane, Douglas, Calvert, Valerie, Petricoin, Emanuel F., Kramer, Liana, Hale, Martha L., Bavari, Sina, Panchal, Rekha G., Hakami, Ramin M.
Publicado 2015

In vitro and in vivo activity of GT-1, a novel siderophore cephalosporin, and GT-055, a broad-spectrum β-lactamase inhibitor, against biothreat and ESKAPE pathogens

por Halasohoris, Stephanie A., Scarff, Jennifer M., Pysz, Lisa M., Lembirik, Sanae, Lemmon, Margaret M., Biek, Donald, Hannah, Brendan, Zumbrun, Steven D., Panchal, Rekha G.
Publicado 2021

The Biophysical Interaction of the Danger-Associated Molecular Pattern (DAMP) Calreticulin with the Pattern-Associated Molecular Pattern (PAMP) Lipopolysaccharide

por Pandya, Unnati M., Egbuta, Chinaza, Abdullah Norman, Trefa M., Chiang, Chih-Yuan (Edward), Wiersma, Valerie R., Panchal, Rekha G., Bremer, Edwin, Eggleton, Paul, Gold, Leslie I
Publicado 2019

Integrating High-Content Imaging and Chemical Genetics to Probe Host Cellular Pathways Critical for Yersinia Pestis Infection

por Kota, Krishna P., Eaton, Brett, Lane, Douglas, Ulrich, Melanie, Ulrich, Ricky, Peyser, Brian D., Robinson, Camenzind G., Jaissle, James G., Pegoraro, Gianluca, Bavari, Sina, Panchal, Rekha G.
Publicado 2013

A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection

por Chiang, Chih-Yuan, Uzoma, Ijeoma, Lane, Douglas J., Memišević, Vesna, Alem, Farhang, Yao, Kuan, Kota, Krishna P., Bavari, Sina, Wallqvist, Anders, Hakami, Ramin M., Panchal, Rekha G.
Publicado 2015

Enhancing the antibacterial activity of polymyxins using a nonantibiotic drug

por Krishnamurthy, Malathy, Lemmon, Margaret M, Falcinelli, Evan M, Sandy, Reuel A, Dootz, Jennifer N, Mott, Tiffany M, Rajamani, Sathish, Schaecher, Kurt E, Duplantier, Allen J, Panchal, Rekha G
Publicado 2019