Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus

por Wang, Yupeng, Khan, Iram F., Boissel, Sandrine, Jarjour, Jordan, Pangallo, Joseph, Thyme, Summer, Baker, David, Scharenberg, Andrew M., Rawlings, David J.
Publicado 2014

Interferon lambda 4 expression is suppressed by the host during viral infection

por Hong, MeeAe, Schwerk, Johannes, Lim, Chrissie, Kell, Alison, Jarret, Abigail, Pangallo, Joseph, Loo, Yueh-Ming, Liu, Shuanghu, Hagedorn, Curt H., Gale, Michael, Savan, Ram
Publicado 2016

Effective, safe, and sustained correction of murine XLA using a UCOE-BTK promoter-based lentiviral vector

por Seymour, Brenda J., Singh, Swati, Certo, Hannah M., Sommer, Karen, Sather, Blythe D., Khim, Socheath, Clough, Courtnee, Hale, Malika, Pangallo, Joseph, Ryu, Byoung Y., Khan, Iram F., Adair, Jennifer E., Rawlings, David J.
Publicado 2021

RNA isoform screens uncover the essentiality and tumor suppressor activity of ultraconserved poison exons

por Thomas, James D., Polaski, Jacob T., Feng, Qing, De Neef, Emma J., Hoppe, Emma R., McSharry, Maria V., Pangallo, Joseph, Gabel, Austin M., Belleville, Andrea E., Watson, Jacqueline, Nkinsi, Naomi T., Berger, Alice H., Bradley, Robert K.
Publicado 2020

Coordinated missplicing of TMEM14C and ABCB7 causes ring sideroblast formation in SF3B1-mutant myelodysplastic syndrome

por Clough, Courtnee A., Pangallo, Joseph, Sarchi, Martina, Ilagan, Janine O., North, Khrystyna, Bergantinos, Rochelle, Stolla, Massiel C., Naru, Jasmine, Nugent, Patrick, Kim, Eunhee, Stirewalt, Derek L., Subramaniam, Arvind R., Abdel-Wahab, Omar, Abkowitz, Janis L., Bradley, Robert K., Doulatov, Sergei
Publicado 2022

Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells

por North, Khrystyna, Benbarche, Salima, Liu, Bo, Pangallo, Joseph, Chen, Sisi, Stahl, Maximilian, Bewersdorf, Jan Philipp, Stanley, Robert F., Erickson, Caroline, Cho, Hana, Pineda, Jose Mario Bello, Thomas, James D., Polaski, Jacob T., Belleville, Andrea E., Gabel, Austin M., Udy, Dylan B., Humbert, Olivier, Kiem, Hans-Peter, Abdel-Wahab, Omar, Bradley, Robert K.
Publicado 2022

Spliceosomal disruption of the non-canonical BAF complex in cancer

por Inoue, Daichi, Chew, Guo-Liang, Liu, Bo, Michel, Brittany C., Pangallo, Joseph, D’Avino, Andrew R., Hitchman, Tyler, North, Khrystyna, Lee, Stanley Chun-Wei, Bitner, Lillian, Block, Ariele, Moore, Amanda R., Yoshimi, Akihide, Escobar-Hoyos, Luisa, Cho, Hana, Penson, Alex, Lu, Sydney X., Taylor, Justin, Chen, Yu, Kadoch, Cigall, Abdel-Wahab, Omar, Bradley, Robert K.
Publicado 2019