The Comparative Oncology Trials Consortium: Using Spontaneously Occurring Cancers in Dogs to Inform the Cancer Drug Development Pathway

por Gordon, Ira, Paoloni, Melissa, Mazcko, Christina, Khanna, Chand
Publicado 2009

A Compendium of Canine Normal Tissue Gene Expression

por Briggs, Joseph, Paoloni, Melissa, Chen, Qing-Rong, Wen, Xinyu, Khan, Javed, Khanna, Chand
Publicado 2011

Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

por Paoloni, Melissa, Davis, Sean, Lana, Susan, Withrow, Stephen, Sangiorgi, Luca, Picci, Piero, Hewitt, Stephen, Triche, Timothy, Meltzer, Paul, Khanna, Chand
Publicado 2009

Comparative Gene Expression Analyses Identify Luminal and Basal Subtypes of Canine Invasive Urothelial Carcinoma That Mimic Patterns in Human Invasive Bladder Cancer

por Dhawan, Deepika, Paoloni, Melissa, Shukradas, Shweta, Choudhury, Dipanwita Roy, Craig, Bruce A., Ramos-Vara, José A., Hahn, Noah, Bonney, Patty L., Khanna, Chand, Knapp, Deborah W.
Publicado 2015

Rapamycin Pharmacokinetic and Pharmacodynamic Relationships in Osteosarcoma: A Comparative Oncology Study in Dogs

por Paoloni, Melissa C., Mazcko, Christina, Fox, Elizabeth, Fan, Timothy, Lana, Susan, Kisseberth, William, Vail, David M., Nuckolls, Kaylee, Osborne, Tanasa, Yalkowsy, Samuel, Gustafson, Daniel, Yu, Yunkai, Cao, Liang, Khanna, Chand
Publicado 2010

Launching a Novel Preclinical Infrastructure: Comparative Oncology Trials Consortium Directed Therapeutic Targeting of TNFα to Cancer Vasculature

por Paoloni, Melissa C., Tandle, Anita, Mazcko, Christina, Hanna, Engy, Kachala, Stefan, LeBlanc, Amy, Newman, Shelley, Vail, David, Henry, Carolyn, Thamm, Douglas, Sorenmo, Karin, Hajitou, Amin, Pasqualini, Renata, Arap, Wadih, Khanna, Chand, Libutti, Steven K.
Publicado 2009

Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma

por Paoloni, Melissa, Mazcko, Christina, Selting, Kimberly, Lana, Susan, Barber, Lisa, Phillips, Jeffrey, Skorupski, Katherine, Vail, David, Wilson, Heather, Biller, Barbara, Avery, Anne, Kiupel, Matti, LeBlanc, Amy, Bernhardt, Anna, Brunkhorst, Beatrice, Tighe, Robert, Khanna, Chand
Publicado 2015

Prospective Molecular Profiling of Canine Cancers Provides a Clinically Relevant Comparative Model for Evaluating Personalized Medicine (PMed) Trials

por Paoloni, Melissa, Webb, Craig, Mazcko, Christina, Cherba, David, Hendricks, William, Lana, Susan, Ehrhart, E. J., Charles, Brad, Fehling, Heather, Kumar, Leena, Vail, David, Henson, Michael, Childress, Michael, Kitchell, Barbara, Kingsley, Christopher, Kim, Seungchan, Neff, Mark, Davis, Barbara, Khanna, Chand, Trent, Jeffrey
Publicado 2014

DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial

por Wolf, Denise M., Yau, Christina, Sanil, Ashish, Glas, Annuska, Petricoin, Emanuel, Wulfkuhle, Julia, Severson, Tesa M., Linn, Sabine, Brown-Swigart, Lamorna, Hirst, Gillian, Buxton, Meredith, DeMichele, Angela, Hylton, Nola, Symmans, Fraser, Yee, Doug, Paoloni, Melissa, Esserman, Laura, Berry, Don, Rugo, Hope, Olopade, Olufunmilayo, van ‘t Veer, Laura
Publicado 2017

A Comparative Oncology Study of Iniparib Defines Its Pharmacokinetic Profile and Biological Activity in a Naturally-Occurring Canine Cancer Model

por Saba, Corey, Paoloni, Melissa, Mazcko, Christina, Kisseberth, William, Burton, Jenna H., Smith, Annette, Wilson-Robles, Heather, Allstadt, Sara, Vail, David, Henry, Carolyn, Lana, Susan, Ehrhart, E. J., Charles, Brad, Kent, Michael, Lawrence, Jessica, Burgess, Kristine, Borgatti, Antonella, Suter, Steve, Woods, Paul, Gordon, Ira, Vrignaud, Patricia, Khanna, Chand, LeBlanc, Amy K.
Publicado 2016

Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2(+) breast cancer in the adaptively randomized I-SPY2 trial

por Clark, Amy S., Yau, Christina, Wolf, Denise M., Petricoin, Emanuel F., van ‘t Veer, Laura J., Yee, Douglas, Moulder, Stacy L., Wallace, Anne M., Chien, A. Jo, Isaacs, Claudine, Boughey, Judy C., Albain, Kathy S., Kemmer, Kathleen, Haley, Barbara B., Han, Hyo S., Forero-Torres, Andres, Elias, Anthony, Lang, Julie E., Ellis, Erin D., Yung, Rachel, Tripathy, Debu, Nanda, Rita, Wulfkuhle, Julia D., Brown-Swigart, Lamorna, Gallagher, Rosa I., Helsten, Teresa, Roesch, Erin, Ewing, Cheryl A., Alvarado, Michael, Crane, Erin P., Buxton, Meredith, Clennell, Julia L., Paoloni, Melissa, Asare, Smita M., Wilson, Amy, Hirst, Gillian L., Singhrao, Ruby, Steeg, Katherine, Asare, Adam, Matthews, Jeffrey B., Berry, Scott, Sanil, Ashish, Melisko, Michelle, Perlmutter, Jane, Rugo, Hope S., Schwab, Richard B., Symmans, W. Fraser, Hylton, Nola M., Berry, Donald A., Esserman, Laura J., DeMichele, Angela M.
Publicado 2021

Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer

por Yee, Douglas, Isaacs, Claudine, Wolf, Denise M., Yau, Christina, Haluska, Paul, Giridhar, Karthik V., Forero-Torres, Andres, Jo Chien, A., Wallace, Anne M., Pusztai, Lajos, Albain, Kathy S., Ellis, Erin D., Beckwith, Heather, Haley, Barbara B., Elias, Anthony D., Boughey, Judy C., Kemmer, Kathleen, Yung, Rachel L., Pohlmann, Paula R., Tripathy, Debu, Clark, Amy S., Han, Hyo S., Nanda, Rita, Khan, Qamar J., Edmiston, Kristen K., Petricoin, Emanuel F., Stringer-Reasor, Erica, Falkson, Carla I., Majure, Melanie, Mukhtar, Rita A., Helsten, Teresa L., Moulder, Stacy L., Robinson, Patricia A., Wulfkuhle, Julia D., Brown-Swigart, Lamorna, Buxton, Meredith, Clennell, Julia L., Paoloni, Melissa, Sanil, Ashish, Berry, Scott, Asare, Smita M., Wilson, Amy, Hirst, Gillian L., Singhrao, Ruby, Asare, Adam L., Matthews, Jeffrey B., Hylton, Nola M., DeMichele, Angela, Melisko, Michelle, Perlmutter, Jane, Rugo, Hope S., Fraser Symmans, W., van‘t Veer, Laura J., Berry, Donald A., Esserman, Laura J.
Publicado 2021