Endoplasmic reticulum stress, degeneration of pancreatic islet β-cells, and therapeutic modulation of the unfolded protein response in diabetes

por Ghosh, Rajarshi, Colon-Negron, Kevin, Papa, Feroz R.
Publicado 2019

X-Box Binding Protein 1 (XBP1s) Is a Critical Determinant of Pseudomonas aeruginosa Homoserine Lactone-Mediated Apoptosis

por Valentine, Cathleen D., Anderson, Marc O., Papa, Feroz R., Haggie, Peter M.
Publicado 2013

Correction: X-Box Binding Protein 1 (XBP1s) Is a Critical Determinant of Pseudomonas aeruginosa Homoserine Lactone-Mediated Apoptosis

por Valentine, Cathleen D., Anderson, Marc O., Papa, Feroz R., Haggie, Peter M.
Publicado 2016

Deletion of the Unfolded Protein Response Transducer IRE1α Is Detrimental to Aging Photoreceptors and to ER Stress-Mediated Retinal Degeneration

por Massoudi, Dawiyat, Gorman, Seán, Kuo, Yien-Ming, Iwawaki, Takao, Oakes, Scott A., Papa, Feroz R., Gould, Douglas B.
Publicado 2023

Small molecule inhibition of IRE1α kinase/RNase has anti-fibrotic effects in the lung

por Thamsen, Maike, Ghosh, Rajarshi, Auyeung, Vincent C., Brumwell, Alexis, Chapman, Harold A., Backes, Bradley J., Perara, Gayani, Maly, Dustin J., Sheppard, Dean, Papa, Feroz R.
Publicado 2019

Nicotinic acetylcholine receptor signaling regulates inositol‐requiring enzyme 1α activation to protect β‐cells against terminal unfolded protein response under irremediable endopl...

por Ishibashi, Tatsuya, Morita, Shuhei, Kishimoto, Shohei, Uraki, Shinsuke, Takeshima, Ken, Furukawa, Yasushi, Inaba, Hidefumi, Ariyasu, Hiroyuki, Iwakura, Hiroshi, Furuta, Hiroto, Nishi, Masahiro, Papa, Feroz R, Akamizu, Takashi
Publicado 2020

Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors

por Wang, Likun, Perera, B. Gayani K., Hari, Sanjay B., Bhhatarai, Barun, Backes, Bradley J., Seeliger, Markus A., Schürer, Stephan C., Oakes, Scott A., Papa, Feroz R., Maly, Dustin J.
Publicado 2012

Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib

por Yamashita, Yusuke, Morita, Shuhei, Hosoi, Hiroki, Kobata, Hiroshi, Kishimoto, Shohei, Ishibashi, Tatsuya, Mishima, Hiroyuki, Kinoshita, Akira, Backes, Bradley J., Yoshiura, Koh-Ichiro, Papa, Feroz R., Sonoki, Takashi, Tamura, Shinobu
Publicado 2020

Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis

por Cha, Seung-Ick, Ryerson, Christopher J, Lee, Joyce S, Kukreja, Jasleen, Barry, Sophia S, Jones, Kirk D, Elicker, Brett M, Kim, Dong Soon, Papa, Feroz R, Collard, Harold R, Wolters, Paul J
Publicado 2012

ATP-Competitive Partial Antagonists of IRE1α’s RNase Segregate Outputs of the UPR

por Feldman, Hannah C., Ghosh, Rajarshi, Auyeung, Vincent C., Mueller, James L., Kim, Jae-Hong, Potter, Zachary E., Vidadala, Venkata N., Perera, B. Gayani K., Olivier, Alina, Backes, Bradley J., Zikherman, Julie, Papa, Feroz R., Maly, Dustin J.
Publicado 2021