Quantitative proteomics and phosphoproteomics of PP2A-PPP2R5D variants reveal deregulation of RPS6 phosphorylation via converging signaling cascades

por Smolen, Kali A., Papke, Cinta M., Swingle, Mark R., Musiyenko, Alla, Li, Chenchen, Salter, E. Alan, Camp, Ashley D., Honkanen, Richard E., Kettenbach, Arminja N.
Publicado 2023

A disorder-related variant (E420K) of a PP2A-regulatory subunit (PPP2R5D) causes constitutively active AKT-mTOR signaling and uncoordinated cell growth

por Papke, Cinta M., Smolen, Kali A., Swingle, Mark R., Cressey, Lauren, Heng, Richard A., Toporsian, Mourad, Deng, Liyong, Hagen, Jacob, Shen, Yufeng, Chung, Wendy K., Kettenbach, Arminja N., Honkanen, Richard E.
Publicado 2021