Combinatorial engineering of N-TIMP2 variants that selectively inhibit MMP9 and MMP14 function in the cell

por Arkadash, Valeria, Radisky, Evette S., Papo, Niv
Publicado 2018

Simultaneous targeting of CD44 and MMP9 catalytic and hemopexin domains as a therapeutic strategy

por Yosef, Gal, Hayun, Hezi, Papo, Niv
Publicado 2021

Generating quantitative binding landscapes through fractional binding selections combined with deep sequencing and data normalization

por Heyne, Michael, Papo, Niv, Shifman, Julia M.
Publicado 2020

Utilizing combinatorial engineering to develop Tie2 targeting antagonistic angiopoetin-2 ligands as candidates for anti-angiogenesis therapy

por Shlamkovich, Tomer, Aharon, Lidan, Barton, William A., Papo, Niv
Publicado 2017

Yeast-based directed-evolution for high-throughput structural stabilization of G protein-coupled receptors (GPCRs)

por Meltzer, M., Zvagelsky, T., Hadad, U., Papo, Niv, Engel, Stanislav
Publicado 2022

Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin

por Dalton, Annamarie C., Shlamkovitch, Tomer, Papo, Niv, Barton, William A.
Publicado 2016

Correction: Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin

por Dalton, Annamarie C., Shlamkovitch, Tomer, Papo, Niv, Barton, William A.
Publicado 2017

Targeting the Tie2–α(v)β(3) integrin axis with bi-specific reagents for the inhibition of angiogenesis

por Shlamkovich, Tomer, Aharon, Lidan, Koslawsky, Dana, Einav, Yulia, Papo, Niv
Publicado 2018

A bi-specific inhibitor targeting IL-17A and MMP-9 reduces invasion and motility in MDA-MB-231 cells

por Koslawsky, Dana, Zaretsky, Marianna, Alcalay, Ron, Mazor, Ohad, Aharoni, Amir, Papo, Niv
Publicado 2018

Mapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries

por Naftaly, Si, Cohen, Itay, Shahar, Anat, Hockla, Alexandra, Radisky, Evette S., Papo, Niv
Publicado 2018

Developing a dual VEGF/PDL1 inhibitor based on high-affinity scFv heterodimers as an anti-cancer therapeutic strategy

por Tzuri, Noam, Yegodayev, Ksenia M., Novoplansky, Ofra, Elkabets, Moshe, Aharoni, Amir, Papo, Niv
Publicado 2023

Engineering Stem Cell Factor Ligands with Different c-Kit Agonistic Potencies

por Tilayov, Tal, Hingaly, Tal, Greenshpan, Yariv, Cohen, Shira, Akabayov, Barak, Gazit, Roi, Papo, Niv
Publicado 2020

Avidity observed between a bivalent inhibitor and an enzyme monomer with a single active site

por Lacham-Hartman, Shiran, Shmidov, Yulia, Radisky, Evette S., Bitton, Ronit, Lukatsky, David B., Papo, Niv
Publicado 2021

PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma

por Ma, Honghai, Hockla, Alexandra, Mehner, Christine, Coban, Matt, Papo, Niv, Radisky, Derek C., Radisky, Evette S.
Publicado 2019

Climbing Up and Down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein–Protein Complexes

por Heyne, Michael, Shirian, Jason, Cohen, Itay, Peleg, Yoav, Radisky, Evette S., Papo, Niv, Shifman, Julia M.
Publicado 2021

Engineered ligand‐based VEGFR antagonists with increased receptor binding affinity more effectively inhibit angiogenesis

por Kapur, Shiven, Silverman, Adam P., Ye, Anne Z., Papo, Niv, Jindal, Darren, Blumenkranz, Mark S., Cochran, Jennifer R.
Publicado 2017

Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14

por Hayun, Hezi, Coban, Matt, Bhagat, Ashok Kumar, Ozer, Eden, Alfonta, Lital, Caulfield, Thomas R., Radisky, Evette S., Papo, Niv
Publicado 2023

Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14

por Hayun, Hezi, Coban, Matt, Bhagat, Ashok Kumar, Ozer, Eden, Alfonta, Lital, Caulfield, Thomas R., Radisky, Evette S., Papo, Niv
Publicado 2023

A KLK4 proteinase substrate capture approach to antagonize PAR1

por Rabinovitch, Eitan, Mihara, Koishiro, Sananes, Amiram, Zaretsky, Marianna, Heyne, Michael, Shifman, Julia, Aharoni, Amir, Hollenberg, Morley D., Papo, Niv
Publicado 2021

A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and α(v)β(3) integrin for osteoporosis therapy

por Zur, Yuval, Rosenfeld, Lior, Keshelman, Chen Anna, Dalal, Nofar, Guterman-Ram, Gali, Orenbuch, Ayelet, Einav, Yulia, Levaot, Noam, Papo, Niv
Publicado 2018