LASSI: A lattice model for simulating phase transitions of multivalent proteins

por Choi, Jeong-Mo, Dar, Furqan, Pappu, Rohit V.
Publicado 2019

Ligand effects on phase separation of multivalent macromolecules

por Ruff, Kiersten M., Dar, Furqan, Pappu, Rohit V.
Publicado 2021

Uncovering Differences in Hydration Free Energies and Structures for Model Compound Mimics of Charged Side Chains of Amino Acids

por Fossat, Martin J., Zeng, Xiangze, Pappu, Rohit V.
Publicado 2021

Polyphasic linkage and the impact of ligand binding on the regulation of biomolecular condensates

por Ruff, Kiersten M., Dar, Furqan, Pappu, Rohit V.
Publicado 2021

Competing interactions give rise to two-state behavior and switch-like transitions in charge-rich intrinsically disordered proteins

por Zeng, Xiangze, Ruff, Kiersten M., Pappu, Rohit V.
Publicado 2022

Hamiltonian Switch Metropolis Monte Carlo Simulations for Improved Conformational Sampling of Intrinsically Disordered Regions Tethered to Ordered Domains of Proteins

por Mittal, Anuradha, Lyle, Nicholas, Harmon, Tyler S., Pappu, Rohit V.
Publicado 2014

Information theoretic measures for quantifying sequence–ensemble relationships of intrinsically disordered proteins

por Cohan, Megan C, Ruff, Kiersten M, Pappu, Rohit V
Publicado 2019

Quantifying charge state heterogeneity for proteins with multiple ionizable residues

por Fossat, Martin J., Posey, Ammon E., Pappu, Rohit V.
Publicado 2021

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins

por Harmon, Tyler S, Holehouse, Alex S, Rosen, Michael K, Pappu, Rohit V
Publicado 2017

Connecting Coil-to-Globule Transitions to Full Phase Diagrams for Intrinsically Disordered Proteins

por Zeng, Xiangze, Holehouse, Alex S., Chilkoti, Ashutosh, Mittag, Tanja, Pappu, Rohit V.
Publicado 2020

Phase separation of protein mixtures is driven by the interplay of homotypic and heterotypic interactions

por Farag, Mina, Borcherds, Wade M., Bremer, Anne, Mittag, Tanja, Pappu, Rohit V.
Publicado 2023

Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions

por Crick, Scott L., Jayaraman, Murali, Frieden, Carl, Wetzel, Ronald, Pappu, Rohit V.
Publicado 2006

Covalently-assembled single-chain protein nanostructures with ultra-high stability

por Bai, Wenqin, Sargent, Cameron J., Choi, Jeong-Mo, Pappu, Rohit V., Zhang, Fuzhong
Publicado 2019

Mesoscale structure–function relationships in mitochondrial transcriptional condensates

por Feric, Marina, Sarfallah, Azadeh, Dar, Furqan, Temiakov, Dmitry, Pappu, Rohit V., Misteli, Tom
Publicado 2022

Unfolded states under folding conditions accommodate sequence-specific conformational preferences with random coil-like dimensions

por Peran, Ivan, Holehouse, Alex S., Carrico, Isaac S., Pappu, Rohit V., Bilsel, Osman, Raleigh, Daniel P.
Publicado 2019

CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins

por Holehouse, Alex S., Das, Rahul K., Ahad, James N., Richardson, Mary O.G., Pappu, Rohit V.
Publicado 2017

Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations

por Farag, Mina, Cohen, Samuel R., Borcherds, Wade M., Bremer, Anne, Mittag, Tanja, Pappu, Rohit V.
Publicado 2022

Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains

por Staller, Max V., Ramirez, Eddie, Kotha, Sanjana R., Holehouse, Alex S., Pappu, Rohit V., Cohen, Barak A.
Publicado 2022

Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments

por Yoo, Tae Yeon, Choi, Jeong-Mo, Conway, William, Yu, Che-Hang, Pappu, Rohit V, Needleman, Daniel J
Publicado 2018

Ion Mobility Mass Spectrometry Uncovers the Impact of the Patterning of Oppositely Charged Residues on the Conformational Distributions of Intrinsically Disordered Proteins

por Beveridge, Rebecca, Migas, Lukasz G., Das, Rahul K., Pappu, Rohit V., Kriwacki, Richard W., Barran, Perdita E.
Publicado 2019