Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21)

por Pappworth, Isabel Y., Kulik, Liudmila, Haluszczak, Catherine, Reuter, Jason W., Holers, V. Michael, Marchbank, Kevin J.
Publicado 2009

Defective B cell ontogeny and humoral immune response in mice prematurely expressing human complement receptor 2 (CR2, CD21) is similar to that seen in aging wild type mice

por Twohig, Jason P., Pappworth, Isabel Y., Sivasankar, Baalasubramanian, Kulik, Liudmila, Bull, Melanie, Holers, V. Michael, Wang, Eddie C.Y., Marchbank, Kevin J.
Publicado 2009

An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy

por Nichols, Eva-Maria, Barbour, Thomas D, Pappworth, Isabel Y, Wong, Edwin K S, Palmer, Jeremy M, Sheerin, Neil S, Pickering, Matthew C, Marchbank, Kevin J
Publicado 2015

Determining the Potential of DNA Damage Response (DDR) Inhibitors in Cervical Cancer Therapy

por Saha, Santu, Rundle, Stuart, Kotsopoulos, Ioannis C., Begbie, Jacob, Howarth, Rachel, Pappworth, Isabel Y., Mukhopadhyay, Asima, Kucukmetin, Ali, Marchbank, Kevin J., Curtin, Nicola
Publicado 2022

A novel C3d-containing oligomeric vaccine provides insight into the viability of testing human C3d-based vaccines in mice

por He, Yong-Gang, Pappworth, Isabel Y., Rossbach, Andreas, Paulin, Joshua, Mavimba, Tarirai, Hayes, Christine, Kulik, Liudmila, Holers, V.Michael, Knight, Andrew M., Marchbank, Kevin J.
Publicado 2018

Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice

por Smith-Jackson, Kate, Yang, Yi, Denton, Harriet, Pappworth, Isabel Y., Cooke, Katie, Barlow, Paul N., Atkinson, John P., Liszewski, M. Kathryn, Pickering, Matthew C., Kavanagh, David, Cook, H. Terence, Marchbank, Kevin J.
Publicado 2019

Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice

por Kerr, Heather, Herbert, Andrew P., Makou, Elisavet, Abramczyk, Dariusz, Malik, Talat H., Lomax-Browne, Hannah, Yang, Yi, Pappworth, Isabel Y., Denton, Harriet, Richards, Anna, Marchbank, Kevin J., Pickering, Matthew C., Barlow, Paul N.
Publicado 2021

Homodimeric Minimal Factor H: In Vivo Tracking and Extended Dosing Studies in Factor H Deficient Mice

por Kamala, Ola, Malik, Talat H., Hallam, Thomas M., Cox, Thomas E., Yang, Yi, Vyas, Falguni, Luli, Saimir, Connelly, Chloe, Gibson, Beth, Smith-Jackson, Kate, Denton, Harriet, Pappworth, Isabel Y., Huang, Lei, Kavanagh, David, Pickering, Matthew C., Marchbank, Kevin J.
Publicado 2021