Runx Transcription Factors in T Cells—What Is Beyond Thymic Development?

por Korinfskaya, Svetlana, Parameswaran, Sreeja, Weirauch, Matthew T., Barski, Artem
Publicado 2021

Human Virus Transcriptional Regulators

por Liu, Xing, Hong, Ted, Parameswaran, Sreeja, Ernst, Kevin, Marazzi, Ivan, Weirauch, Matthew T., Fuxman Bass, Juan I.
Publicado 2020

Small molecule allosteric uncoupling of microtubule depolymerase activity from motility in human Kinesin-5 during mitotic spindle assembly

por Kim, Catherine D., Kim, Elizabeth D., Liu, Liqiong, Buckley, Rebecca S., Parameswaran, Sreeja, Kim, Sunyoung, Wojcik, Edward J.
Publicado 2019

Runx1 shapes the chromatin landscape via a cascade of direct and indirect targets

por Hass, Matthew R., Brissette, Daniel, Parameswaran, Sreeja, Pujato, Mario, Donmez, Omer, Kottyan, Leah C., Weirauch, Matthew T., Kopan, Raphael
Publicado 2021

Comprehensive Review of Steroid-Sensitive Nephrotic Syndrome Genetic Risk Loci and Transcriptional Regulation as a Possible Mechanistic Link to Disease Risk

por Stone, Hillarey K., Parameswaran, Sreeja, Eapen, Amy A., Chen, Xiaoting, Harley, John B., Devarajan, Prasad, Weirauch, Matthew T., Kottyan, Leah
Publicado 2020

Lineage tracing of newly accrued nuclei in skeletal myofibers uncovers distinct transcripts and interplay between nuclear populations

por Sun, Chengyi, Swoboda, Casey O., Petrany, Michael J., Parameswaran, Sreeja, VonHandorf, Andrew, Weirauch, Matthew T., Lepper, Christoph, Millay, Douglas P.
Publicado 2023

After the Infection: A Survey of Pathogens and Non-communicable Human Disease

por Lape, Michael, Schnell, Daniel, Parameswaran, Sreeja, Ernst, Kevin, Salomonis, Nathan, Martin, Lisa J., Harnett, Brett M., Kottyan, Leah C., Weirauch, Matthew T.
Publicado 2023

CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants

por Bray, David, Hook, Heather, Zhao, Rose, Keenan, Jessica L., Penvose, Ashley, Osayame, Yemi, Mohaghegh, Nima, Chen, Xiaoting, Parameswaran, Sreeja, Kottyan, Leah C., Weirauch, Matthew T., Siggers, Trevor
Publicado 2022

IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility

por Song, Ran, Gao, Yajing, Dozmorov, Igor, Malladi, Venkat, Saha, Irene, McDaniel, Margaret M., Parameswaran, Sreeja, Liang, Chaoying, Arana, Carlos, Zhang, Bo, Wakeland, Benjamin, Zhou, Jinchun, Weirauch, Matthew T., Kottyan, Leah C., Wakeland, Edward K., Pasare, Chandrashekhar
Publicado 2021

maxATAC: Genome-scale transcription-factor binding prediction from ATAC-seq with deep neural networks

por Cazares, Tareian A., Rizvi, Faiz W., Iyer, Balaji, Chen, Xiaoting, Kotliar, Michael, Bejjani, Anthony T., Wayman, Joseph A., Donmez, Omer, Wronowski, Benjamin, Parameswaran, Sreeja, Kottyan, Leah C., Barski, Artem, Weirauch, Matthew T., Prasath, V. B. Surya, Miraldi, Emily R.
Publicado 2023

Global discovery of lupus genetic risk variant allelic enhancer activity

por Lu, Xiaoming, Chen, Xiaoting, Forney, Carmy, Donmez, Omer, Miller, Daniel, Parameswaran, Sreeja, Hong, Ted, Huang, Yongbo, Pujato, Mario, Cazares, Tareian, Miraldi, Emily R., Ray, John P., de Boer, Carl G., Harley, John B., Weirauch, Matthew T., Kottyan, Leah C.
Publicado 2021

Epstein–Barr virus nuclear antigen 2 extensively rewires the human chromatin landscape at autoimmune risk loci

por Hong, Ted, Parameswaran, Sreeja, Donmez, Omer A., Miller, Daniel, Forney, Carmy, Lape, Michael, Saint Just Ribeiro, Mariana, Liang, Jun, Edsall, Lee E., Magnusen, Albert F., Miller, William, Chepelev, Iouri, Harley, John B., Zhao, Bo, Kottyan, Leah C., Weirauch, Matthew T.
Publicado 2021

Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer

por Oatman, Nicole, Dasgupta, Nupur, Arora, Priyanka, Choi, Kwangmin, Gawali, Mruniya V., Gupta, Nishtha, Parameswaran, Sreeja, Salomone, Joseph, Reisz, Julie A., Lawler, Sean, Furnari, Frank, Brennan, Cameron, Wu, Jianqiang, Sallans, Larry, Gudelsky, Gary, Desai, Pankaj, Gebelein, Brian, Weirauch, Matthew T., D’Alessandro, Angelo, Komurov, Kakajan, Dasgupta, Biplab
Publicado 2021

Epigenetic and transcriptional dysregulation in CD4+ T cells in patients with atopic dermatitis

por Eapen, Amy A., Parameswaran, Sreeja, Forney, Carmy, Edsall, Lee E., Miller, Daniel, Donmez, Omer, Dunn, Katelyn, Lu, Xiaoming, Granitto, Marissa, Rowden, Hope, Magier, Adam Z., Pujato, Mario, Chen, Xiaoting, Kaufman, Kenneth, Bernstein, David I., Devonshire, Ashley L., Rothenberg, Marc E., Weirauch, Matthew T., Kottyan, Leah C.
Publicado 2022

β‐catenin cancer–enhancing genomic regions axis is involved in the development of fibrolamellar hepatocellular carcinoma

por Gulati, Ruhi, Johnston, Michael, Rivas, Maria, Cast, Ashley, Kumbaji, Meenasri, Hanlon, Margaret A., Lee, Sanghoon, Zhou, Ping, Lake, Charissa, Schepers, Emily, Min, Kyung‐Won, Yoon, Je‐Hyun, Karns, Rebekah, Reid, Lola M., Lopez‐Terrada, Dolores, Timchenko, Lubov, Parameswaran, Sreeja, Weirauch, Matthew T., Ranganathan, Sarangarajan, Bondoc, Alexander, Geller, James, Tiao, Gregory, Shin, Soona, Timchenko, Nikolai
Publicado 2022

GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network

por Namjou, Bahram, Lingren, Todd, Huang, Yongbo, Parameswaran, Sreeja, Cobb, Beth L., Stanaway, Ian B., Connolly, John J., Mentch, Frank D., Benoit, Barbara, Niu, Xinnan, Wei, Wei-Qi, Carroll, Robert J., Pacheco, Jennifer A., Harley, Isaac T. W., Divanovic, Senad, Carrell, David S., Larson, Eric B., Carey, David J., Verma, Shefali, Ritchie, Marylyn D., Gharavi, Ali G., Murphy, Shawn, Williams, Marc S., Crosslin, David R., Jarvik, Gail P., Kullo, Iftikhar J., Hakonarson, Hakon, Li, Rongling, Xanthakos, Stavra A., Harley, John B.
Publicado 2019

TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation

por Ho, Jessica Sook Yuin, Mok, Bobo Wing-Yee, Campisi, Laura, Jordan, Tristan, Yildiz, Soner, Parameswaran, Sreeja, Wayman, Joseph A., Gaudreault, Natasha N., Meekins, David A., Indran, Sabarish V., Morozov, Igor, Trujillo, Jessie D., Fstkchyan, Yesai S., Rathnasinghe, Raveen, Zhu, Zeyu, Zheng, Simin, Zhao, Nan, White, Kris, Ray-Jones, Helen, Malysheva, Valeriya, Thiecke, Michiel J., Lau, Siu-Ying, Liu, Honglian, Zhang, Anna Junxia, Lee, Andrew Chak-Yiu, Liu, Wen-Chun, Jangra, Sonia, Escalera, Alba, Aydillo, Teresa, Melo, Betsaida Salom, Guccione, Ernesto, Sebra, Robert, Shum, Elaine, Bakker, Jan, Kaufman, David A., Moreira, Andre L., Carossino, Mariano, Balasuriya, Udeni B.R., Byun, Minji, Albrecht, Randy A., Schotsaert, Michael, Garcia-Sastre, Adolfo, Chanda, Sumit K., Miraldi, Emily R., Jeyasekharan, Anand D., TenOever, Benjamin R., Spivakov, Mikhail, Weirauch, Matthew T., Heinz, Sven, Chen, Honglin, Benner, Christopher, Richt, Juergen A., Marazzi, Ivan
Publicado 2021

Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus

por Yin, Xianyong, Kim, Kwangwoo, Suetsugu, Hiroyuki, Bang, So-Young, Wen, Leilei, Koido, Masaru, Ha, Eunji, Liu, Lu, Sakamoto, Yuma, Jo, Sungsin, Leng, Rui-Xue, Otomo, Nao, Laurynenka, Viktoryia, Kwon, Young-Chang, Sheng, Yujun, Sugano, Nobuhiko, Hwang, Mi Yeong, Li, Weiran, Mukai, Masaya, Yoon, Kyungheon, Cai, Minglong, Ishigaki, Kazuyoshi, Chung, Won Tae, Huang, He, Takahashi, Daisuke, Lee, Shin-Seok, Wang, Mengwei, Karino, Kohei, Shim, Seung-Cheol, Zheng, Xiaodong, Miyamura, Tomoya, Kang, Young Mo, Ye, Dongqing, Nakamura, Junichi, Suh, Chang-Hee, Tang, Yuanjia, Motomura, Goro, Park, Yong-Beom, Ding, Huihua, Kuroda, Takeshi, Choe, Jung-Yoon, Li, Chengxu, Niiro, Hiroaki, Park, Youngho, Shen, Changbing, Miyamoto, Takeshi, Ahn, Ga-Young, Fei, Wenmin, Takeuchi, Tsutomu, Shin, Jung-Min, Li, Keke, Kawaguchi, Yasushi, Lee, Yeon-Kyung, Wang, Yongfei, Amano, Koichi, Park, Dae Jin, Yang, Wanling, Tada, Yoshifumi, Yamaji, Ken, Shimizu, Masato, Atsumi, Takashi, Suzuki, Akari, Sumida, Takayuki, Okada, Yukinori, Matsuda, Koichi, Matsuo, Keitaro, Kochi, Yuta, Kottyan, Leah C, Weirauch, Matthew T, Parameswaran, Sreeja, Eswar, Shruti, Salim, Hanan, Chen, Xiaoting, Yamamoto, Kazuhiko, Harley, John B, Ohmura, Koichiro, Kim, Tae-Hwan, Yang, Sen, Yamamoto, Takuaki, Kim, Bong-Jo, Shen, Nan, Ikegawa, Shiro, Lee, Hye-Soon, Zhang, Xuejun, Terao, Chikashi, Cui, Yong, Bae, Sang-Cheol
Publicado 2021