Are different events involved in the development of sporadic versus hereditary tumours? The possible importance of the microenvironment in hereditary cancer.

por Paraskeva, C., Williams, A. C.
Publicado 1990

Elevated production of growth factor by human premalignant colon adenomas and a derived epithelial cell line.

por Wigley, C. B., Paraskeva, C., Coventry, R.
Publicado 1986

In vitro culture of human foetal colonic epithelial cells and their transformation with origin minus SV40 DNA.

por Berry, R. D., Powell, S. C., Paraskeva, C.
Publicado 1988

Selective killing of contaminating human fibroblasts in epithelial cultures derived from colorectal tumours using an anti Thy-1 antibody-ricin conjugate.

por Paraskeva, C., Buckle, B. G., Thorpe, P. E.
Publicado 1985

Cell-cell contact and specific cytokines inhibit apoptosis of colonic epithelial cells: growth factors protect against c-myc-independent apoptosis.

por Hague, A., Hicks, D. J., Bracey, T. S., Paraskeva, C.
Publicado 1997

Abrogation of the radiation-induced G2 checkpoint by the staurosporine derivative UCN-01 is associated with radiosensitisation in a subset of colorectal tumour cell lines

por Playle, L C, Hicks, D J, Qualtrough, D, Paraskeva, C
Publicado 2002

The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro

por Qualtrough, D, Singh, K, Banu, N, Paraskeva, C, Pignatelli, M
Publicado 2009

TGF-beta expression in the human colon: differential immunostaining along crypt epithelium.

por Avery, A., Paraskeva, C., Hall, P., Flanders, K. C., Sporn, M., Moorghen, M.
Publicado 1993

Transcriptional down-regulation of the retinoblastoma protein is associated with differentiation and apoptosis in human colorectal epithelial cells

por Guy, M, Moorghen, M, Bond, J A, Collard, T J, Paraskeva, C, Williams, A C
Publicado 2001

Increased NF-κB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells

por Smartt, H J M, Elder, D J E, Hicks, D J, Williams, N A, Paraskeva, C
Publicado 2003

Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis

por Hague, A, Hicks, D J, Hasan, F, Smartt, H, Cohen, G M, Paraskeva, C, MacFarlane, M
Publicado 2005

The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cells

por Collard, T J, Urban, B C, Patsos, H A, Hague, A, Townsend, P A, Paraskeva, C, Williams, A C
Publicado 2012

Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting canc...

por Morgan, R G, Molnár, E, Jones, R F, Collard, T J, Lane, J D, Greenhough, A, Paraskeva, C, Williams, A C
Publicado 2015

Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: cooperation between src and HGF/Met in invasion.

por Empereur, S., Djelloul, S., Di Gioia, Y., Bruyneel, E., Mareel, M., Van Hengel, J., Van Roy, F., Comoglio, P., Courtneidge, S., Paraskeva, C., Chastre, E., Gespach, C.
Publicado 1997

β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive effica...

por Smartt, H J M, Greenhough, A, Ordóñez-Morán, P, Al-Kharusi, M, Collard, T J, Mariadason, J M, Huelsken, J, Williams, A C, Paraskeva, C
Publicado 2012

VEGF(165)b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro- and antiangiogenic VEGF-A isoforms has...

por Varey, A H R, Rennel, E S, Qiu, Y, Bevan, H S, Perrin, R M, Raffy, S, Dixon, A R, Paraskeva, C, Zaccheo, O, Hassan, A B, Harper, S J, Bates, D O
Publicado 2008