Analyses of the combination of 6-MP and dasatinib in cell culture

por KAUR, GURMEET, BEHRSING, HOLGER, PARCHMENT, RALPH E., MILLIN, MYRTLE DAVIS, TEICHER, BEVERLY A.
Publicado 2013

Advances in using PARP inhibitors to treat cancer

por Kummar, Shivaani, Chen, Alice, Parchment, Ralph E, Kinders, Robert J, Ji, Jay, Tomaszewski, Joseph E, Doroshow, James H
Publicado 2012

Modeling Pharmacodynamic Response to the Poly(ADP-Ribose) Polymerase Inhibitor ABT-888 in Human Peripheral Blood Mononuclear Cells

por Ji, Jiuping, Kinders, Robert J., Zhang, Yiping, Rubinstein, Larry, Kummar, Shivaani, Parchment, Ralph E., Tomaszewski, Joseph E., Doroshow, James H.
Publicado 2011

PARP Inhibitor Applicability: Detailed Assays for Homologous Recombination Repair Pathway Components

por O’Sullivan Coyne, Geraldine, Karlovich, Chris, Wilsker, Deborah, Voth, Andrea Regier, Parchment, Ralph E, Chen, Alice P, Doroshow, James H
Publicado 2022

Synergistic antitumor activity of oncolytic reovirus and chemotherapeutic agents in non-small cell lung cancer cells

por Sei, Shizuko, Mussio, Jodie K, Yang, Quan-en, Nagashima, Kunio, Parchment, Ralph E, Coffey, Matthew C, Shoemaker, Robert H, Tomaszewski, Joseph E
Publicado 2009

Development of a quantitative pharmacodynamic assay for apoptosis in fixed tumor tissue and its application in distinguishing cytotoxic drug—induced DNA double strand breaks from D...

por Dull, Angie B., Wilsker, Deborah, Hollingshead, Melinda, Mazcko, Christina, Annunziata, Christina M., LeBlanc, Amy K., Doroshow, James H., Kinders, Robert J., Parchment, Ralph E.
Publicado 2018

Antibody-independent capture of circulating tumor cells of non-epithelial origin with the ApoStream(®) system

por Balasubramanian, Priya, Kinders, Robert J., Kummar, Shivaani, Gupta, Vishal, Hasegawa, David, Menachery, Anoop, Lawrence, Scott M., Wang, Lihua, Ferry-Galow, Katherine, Davis, Darren, Parchment, Ralph E., Tomaszewski, Joseph E., Doroshow, James H.
Publicado 2017

Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay

por Ji, Jiuping, Zhang, Yiping, Redon, Christophe E., Reinhold, William C., Chen, Alice P., Fogli, Laura K., Holbeck, Susan L., Parchment, Ralph E., Hollingshead, Melinda, Tomaszewski, Joseph E., Dudon, Quentin, Pommier, Yves, Doroshow, James H., Bonner, William M.
Publicado 2017

Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3ζ protein and represses lung cancer metastasis

por Chen, Zibo, Zheng, Lin, Chen, Yulong, Liu, Xiuxia, Kawakami, Masanori, Mustachio, Lisa Maria, Roszik, Jason, Ferry-Galow, Katherine V., Parchment, Ralph E., Liu, Xin, Andresson, Thorkell, Duncan, Gerard, Kurie, Jonathan M., Rodriguez-Canales, Jaime, Liu, Xi, Dmitrovsky, Ethan
Publicado 2022

Development and Validation of an Immunoassay for Quantification of Topoisomerase I in Solid Tumor Tissues

por Pfister, Thomas D., Hollingshead, Melinda, Kinders, Robert J., Zhang, Yiping, Evrard, Yvonne A., Ji, Jiuping, Khin, Sonny A., Borgel, Suzanne, Stotler, Howard, Carter, John, Divelbiss, Raymond, Kummar, Shivaani, Pommier, Yves, Parchment, Ralph E., Tomaszewski, Joseph E., Doroshow, James H.
Publicado 2012

ATR inhibition reverses the resistance of homologous recombination deficient MGMT(low)/MMR(proficient) cancer cells to temozolomide

por El Touny, Lara H., Hose, Curtis, Connelly, John, Harris, Erik, Monks, Anne, Dull, Angie B., Wilsker, Deborah F., Hollingshead, Melinda G., Gottholm-Ahalt, Michelle, Alcoser, Sergio Y., Mullendore, Michael E., Parchment, Ralph E., Doroshow, James H., Teicher, Beverly A., Rapisarda, Annamaria
Publicado 2021

Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo

por Tyurina, Yulia Y., Kapralov, Alexandr A., Tyurin, Vladimir A., Shurin, Galina, Amoscato, Andrew A., Rajasundaram, Dhivyaa, Tian, Hua, Bunimovich, Yuri L., Nefedova, Yulia, Herrick, William G., Parchment, Ralph E., Doroshow, James H., Bayir, Hulya, Srivastava, Apurva K., Kagan, Valerian E.
Publicado 2023

Combination therapy with pazopanib and tivantinib modulates VEGF and c-MET levels in refractory advanced solid tumors

por Kummar, Shivaani, Srivastava, Apurva K., Navas, Tony, Cecchi, Fabiola, Lee, Young H., Bottaro, Donald P., Park, Sook Ryun, Do, Khanh T., Jeong, Woondong, Johnson, Barry C., Voth, Andrea R., Rubinstein, Larry, Wright, John J., Parchment, Ralph E., Doroshow, James H., Chen, Alice P.
Publicado 2021

Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells

por Navas, Tony, Pfister, Thomas D., Colantonio, Simona, Aziz, Amina, Dieckman, Lynda, Saul, Richard G., Kaczmarczyk, Jan, Borgel, Suzanne, Alcoser, Sergio Y., Hollingshead, Melinda G., Lee, Young H., Bottaro, Donald P., Hiltke, Tara, Whiteley, Gordon, Takebe, Naoko, Kinders, Robert J., Parchment, Ralph E., Tomaszewski, Joseph E., Doroshow, James H.
Publicado 2018

Intravenous 5-fluoro-2′-deoxycytidine administered with tetrahydrouridine increases the proportion of p16-expressing circulating tumor cells in patients with advanced solid tumors...

por Coyne, Geraldine O.’Sullivan, Wang, Lihua, Zlott, Jennifer, Juwara, Lamin, Covey, Joseph M., Beumer, Jan H., Cristea, Mihaela C., Newman, Edward M., Koehler, Stephen, Nieva, Jorge J., Garcia, Agustin A., Gandara, David R., Miller, Brandon, Khin, Sonny, Miller, Sarah B., Steinberg, Seth M., Rubinstein, Larry, Parchment, Ralph E., Kinders, Robert J., Piekarz, Richard L., Kummar, Shivaani, Chen, Alice P., Doroshow, James H.
Publicado 2020

Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas

por Coyne, Geraldine O'Sullivan, Kummar, Shivaani, Meehan, Robert S., Do, Khanh, Collins, Jerry M., Anderson, Larry, Ishii, Kazusa, Takebe, Naoko, Zlott, Jennifer, Juwara, Lamin, Piekarz, Richard, Streicher, Howard, Sharon, Elad, Rubinstein, Larry, Voth, Andrea Regier, Lozier, Jay, Dull, Angie B., Wilsker, Deborah, Hinoue, Toshinori, Laird, Peter W., Ferry-Galow, Katherine V., Kinders, Robert J., Parchment, Ralph E., Doroshow, James H., Chen, Alice P.
Publicado 2020