Novel Fas-TNFR chimeras that prevent Fas ligand-mediated kill and signal synergistically to enhance CAR T cell efficacy

por McKenzie, Callum, El-Kholy, Mohamed, Parekh, Farhaan, Robson, Mathew, Lamb, Katarina, Allen, Christopher, Sillibourne, James, Cordoba, Shaun, Thomas, Simon, Pule, Martin
Publicado 2023

Large-scale manufacturing of base-edited chimeric antigen receptor T cells

por Woodruff, Rosie, Parekh, Farhaan, Lamb, Katarina, Mekkaoui, Leila, Allen, Christopher, Smetanova, Katerina, Huang, Jasmine, Williams, Alex, Toledo, Gerardo Santiago, Lilova, Koki, Roddie, Claire, Sillibourne, James, Pule, Martin
Publicado 2023

Lentiviral Vector Purification Using Genetically Encoded Biotin Mimic in Packaging Cell

por Mekkaoui, Leila, Parekh, Farhaan, Kotsopoulou, Ekaterini, Darling, David, Dickson, Glenda, Cheung, Gordon W., Chan, Lucas, MacLellan-Gibson, Kirsty, Mattiuzzo, Giada, Farzaneh, Farzin, Takeuchi, Yasuhiro., Pule, Martin
Publicado 2018

A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats

por Nannini, Francesco, Parekh, Farhaan, Wawrzyniecka, Patrycja, Mekkaoui, Leila, Righi, Matteo, Dastjerdi, Fatemeh V., Yeung, Jenny, Roddie, Claire, Bai, Yuchen, Ma, Biao, Ferrari, Mathieu, Onuoha, Shimobi, Chester, Kerry, Pule, Martin
Publicado 2020

Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments

por Nannini, Francesco, Senicar, Lenart, Parekh, Farhaan, Kong, Khai J., Kinna, Alexander, Bughda, Reyisa, Sillibourne, James, Hu, Xihao, Ma, Biao, Bai, Yuchen, Ferrari, Mathieu, Pule, Martin A., Onuoha, Shimobi C.
Publicado 2020

Characterization of a Novel ACE2-Based Therapeutic with Enhanced Rather than Reduced Activity against SARS-CoV-2 Variants

por Ferrari, Mathieu, Mekkaoui, Leila, Ilca, F. Tudor, Akbar, Zulaikha, Bughda, Reyisa, Lamb, Katarina, Ward, Katarzyna, Parekh, Farhaan, Karattil, Rajeev, Allen, Christopher, Wu, Philip, Baldan, Vania, Mattiuzzo, Giada, Bentley, Emma M., Takeuchi, Yasuhiro, Sillibourne, James, Datta, Preeta, Kinna, Alexander, Pule, Martin, Onuoha, Shimobi C.
Publicado 2021