Inhibition of Hedgehog Signaling in Fibroblasts, Pancreatic, and Lung Tumor Cells by Oxy186, an Oxysterol Analogue with Drug-Like Properties

por Wang, Feng, Stappenbeck, Frank, Parhami, Farhad
Publicado 2019

Oxy210, a Semi-Synthetic Oxysterol, Inhibits Profibrotic Signaling in Cellular Models of Lung and Kidney Fibrosis

por Wang, Feng, Stappenbeck, Frank, Parhami, Farhad
Publicado 2023

Abstract P13. Oxy133, A Novel Osteogenic Agent, Promotes Bone Regeneration In The Rat Alveolar Cleft Model

por Bakshi, Reena, Hokugo, Akishige, Zhou, Situo, Stappenbeck, Frank, Parhami, Farhad, Jarrahy, Reza
Publicado 2017

Inhibition of Non-Small Cell Lung Cancer Cells by Oxy210, an Oxysterol-Derivative that Antagonizes TGFβ and Hedgehog Signaling

por Stappenbeck, Frank, Wang, Feng, Tang, Liu-Ya, Zhang, Ying E., Parhami, Farhad
Publicado 2019

Bone Density and Hyperlipidemia: The T-lymphocyte Connection

por Graham, Lucia S, Tintut, Yin, Parhami, Farhad, Kitchen, Christina MR, Ivanov, Yevgeniv, Tetradis, Sotirios, Effros, Rita B
Publicado 2010

Oxy210, a novel inhibitor of hedgehog and TGF‐β signalling, ameliorates hepatic fibrosis and hypercholesterolemia in mice

por Hui, Simon T., Wang, Feng, Stappenbeck, Frank, French, Samuel W., Magyar, Clara E., Parhami, Farhad, Lusis, Aldons J.
Publicado 2021

Oxy210, a Semi-Synthetic Oxysterol, Exerts Anti-Inflammatory Effects in Macrophages via Inhibition of Toll-like Receptor (TLR) 4 and TLR2 Signaling and Modulation of Macrophage Pol...

por Wang, Feng, Stappenbeck, Frank, Tang, Liu-Ya, Zhang, Ying E., Hui, Simon T., Lusis, Aldons J., Parhami, Farhad
Publicado 2022

Osteogenic Oxysterol, 20(S)-Hydroxycholesterol, Induces Notch Target Gene Expression in Bone Marrow Stromal Cells

por Kim, Woo-Kyun, Meliton, Vicente, Tetradis, Sotirios, Weinmaster, Gerry, Hahn, Theodore J, Carlson, Marc, Nelson, Stanley F, Parhami, Farhad
Publicado 2010

Oxysterol derivatives Oxy186 and Oxy210 inhibit WNT signaling in non-small cell lung cancer

por Tang, Liu-Ya, Spezia, Marie, Chen, Ting, Shin, Jee-Hye, Wang, Feng, Stappenbeck, Frank, Lebensohn, Andres M., Parhami, Farhad, Zhang, Ying E.
Publicado 2022

Identification of Anti-Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Oxysterol Derivatives In Vitro

por Ohashi, Hirofumi, Wang, Feng, Stappenbeck, Frank, Tsuchimoto, Kana, Kobayashi, Chisa, Saso, Wakana, Kataoka, Michiyo, Yamasaki, Masako, Kuramochi, Kouji, Muramatsu, Masamichi, Suzuki, Tadaki, Sureau, Camille, Takeda, Makoto, Wakita, Takaji, Parhami, Farhad, Watashi, Koichi
Publicado 2021