Inhibition of DOT1L by Half-Selenopsammaplin A Analogs Suppresses Tumor Growth and EMT-Mediated Metastasis in Triple-Negative Breast Cancer

por Byun, Woong Sub, Lee, Gyu Ho, Park, Hyeung-geun, Lee, Sang Kook
Publicado 2020

Synthesis of chiral malonates by α-alkylation of 2,2-diphenylethyl tert-butyl malonates via enantioselective phase-transfer catalysis

por Guo, Zhibin, Oh, Daehyun, Sagong, Min, Yang, Jewon, Lee, Geumwoo, Park, Hyeung-geun
Publicado 2023

Enantioselective Synthesis of (+)-Coerulescine by a Phase-Transfer Catalytic Allylation of Diphenylmethyl tert-Butyl α-(2-Nitrophenyl)Malonate

por Lee, Sangki, Yang, Jewon, Yang, Sehun, Lee, Geumwoo, Oh, Daehyun, Ha, Min Woo, Hong, Suckchang, Park, Hyeung-geun
Publicado 2020

Inhibition of Streptococcus mutans adhesion and biofilm formation with small-molecule inhibitors of sortase A from Juniperus chinensis

por Cho, Eunji, Hwang, Ji-Yeon, Park, Jae Sung, Oh, Daehyun, Oh, Dong-Chan, Park, Hyeung-Geun, Shin, Jongheon, Oh, Ki-Bong
Publicado 2022

Pharmacological use of a novel scaffold, anomeric N,N-diarylamino tetrahydropyran: molecular similarity search, chemocentric target profiling, and experimental evidence

por Venkanna, Arramshetti, Kwon, Oh Wook, Afzal, Sualiha, Jang, Cheongyun, Cho, Kyo Hee, Yadav, Dharmendra K., Kim, Kang, Park, Hyeung-geun, Chun, Kwang-Hoon, Kim, Sun Yeou, Kim, Mi-hyun
Publicado 2017

Optimization of 2-Aminoquinazolin-4-(3H)-one Derivatives as Potent Inhibitors of SARS-CoV-2: Improved Synthesis and Pharmacokinetic Properties

por Shin, Young Sup, Lee, Jun Young, Jeon, Sangeun, Cho, Jung-Eun, Myung, Subeen, Jang, Min Seong, Kim, Seungtaek, Song, Jong Hwan, Kim, Hyoung Rae, Park, Hyeung-geun, Jeong, Lak Shin, Park, Chul Min
Publicado 2022

Targeting Histone Methyltransferase DOT1L by a Novel Psammaplin A Analog Inhibits Growth and Metastasis of Triple-Negative Breast Cancer

por Byun, Woong Sub, Kim, Won Kyung, Han, Hae Ju, Chung, Hwa-Jin, Jang, Kyungkuk, Kim, Han Sun, Kim, Sunghwa, Kim, Donghwa, Bae, Eun Seo, Park, Sunghyouk, Lee, Jeeyeon, Park, Hyeung-geun, Lee, Sang Kook
Publicado 2019