Editorial: Interactions Between Small Molecule Ligands and Target Enzymes

por Kim, Sung-Kun, Park, Ki Duk, Lee, Dong-Woo
Publicado 2021

Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3ß and CDK5 following traumatic brain injury

por Wilson, Sarah M., Ki Yeon, Seul, Yang, Xiao-Fang, Park, Ki Duk, Khanna, Rajesh
Publicado 2014

Antioxidant and Anti-Inflammatory Activities of a Natural Compound, Shizukahenriol, through Nrf2 Activation

por Park, Jong-Hyun, Choi, Ji Won, Ju, Eun Ji, Pae, Ae Nim, Park, Ki Duk
Publicado 2015

9-O-butyl-13-(4-isopropylbenzyl)berberine, KR-72, Is a Potent Antifungal Agent That Inhibits the Growth of Cryptococcus neoformans by Regulating Gene Expression

por Bang, Soohyun, Kwon, Hyojeong, Hwang, Hyun Sook, Park, Ki Duk, Kim, Sung Uk, Bahn, Yong-Sun
Publicado 2014

The Novel Neuroprotective Compound KMS99220 Has an Early Anti-neuroinflammatory Effect via AMPK and HO-1, Independent of Nrf2

por Lee, Ji Ae, Kim, Hye Ri, Kim, Jiyoung, Park, Ki Duk, Kim, Dong Jin, Hwang, Onyou
Publicado 2018

Synthesis of Novel Dihydropyridothienopyrimidin-4,9-dione Derivatives

por Kim, Youngjae, Kim, Minjoo, Park, Mooseong, Tae, Jinsung, Baek, Du-Jong, Park, Ki Duk, Choo, Hyunah
Publicado 2015

Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2,5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compounds

por Farag, Ahmed K., Hassan, Ahmed H. E., Ahn, Byung Sun, Park, Ki Duk, Roh, Eun Joo
Publicado 2019

Modulation of CRMP2 via (S)-Lacosamide shows therapeutic promise but is ultimately ineffective in a mouse model of CLN6-Batten disease

por White, Katherine A., Cain, Jacob T., Magee, Helen, Yeon, Seul Ki, Park, Ki Duk, Khanna, Rajesh, Weimer, Jill M.
Publicado 2019

Chimeric Agents Derived from the Functionalized Amino Acid, Lacosamide, and the α-Aminoamide, Safinamide: Evaluation of Their Inhibitory Actions on Voltage-Gated Sodium Channels, a...

por Park, Ki Duk, Yang, Xiao-Fang, Dustrude, Erik T., Wang, Yuying, Ripsch, Matthew S., White, Fletcher A., Khanna, Rajesh, Kohn, Harold
Publicado 2014

Efficacy of (S)-lacosamide in preclinical models of cephalic pain

por Moutal, Aubin, Eyde, Nathan, Telemi, Edwin, Park, Ki Duk, Xie, Jennifer Y., Dodick, David W., Porreca, Frank, Khanna, Rajesh
Publicado 2016

Hydroxycholesterol Levels in the Serum and Cerebrospinal Fluid of Patients with Neuromyelitis Optica Revealed by LC-Ag(+)CIS/MS/MS and LC-ESI/MS/MS with Picolinic Derivatization: I...

por Cha, Eunju, Lee, Kang Mi, Park, Ki Duk, Park, Kyung Seok, Lee, Kwang-Woo, Kim, Sung-Min, Lee, Jaeick
Publicado 2016

Melatonin Analogues Potently Inhibit MAO-B and Protect PC12 Cells against Oxidative Stress

por Elkamhawy, Ahmed, Woo, Jiyu, Gouda, Noha A., Kim, Jushin, Nada, Hossam, Roh, Eun Joo, Park, Ki Duk, Cho, Jungsook, Lee, Kyeong
Publicado 2021

A Retro-Aldol Reaction Prompted the Evolvability of a Phosphotransferase System for the Utilization of a Rare Sugar

por Joo, Yunhye, Sung, Jae-Yoon, Shin, Sun-Mi, Park, Sun Jun, Kim, Kyoung Su, Park, Ki Duk, Kim, Seong-Bo, Lee, Dong-Woo
Publicado 2023

Discovery of N-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide: a novel, selective, and competitive indole-based lead inhibitor for human monoamine oxidase B

por Elkamhawy, Ahmed, Paik, Sora, Kim, Hyeon Jeong, Park, Jong-Hyun, Londhe, Ashwini M., Lee, Kyeong, Pae, Ae Nim, Park, Ki Duk, Roh, Eun Joo
Publicado 2020

Highly Potent, Selective, and Competitive Indole-Based MAO-B Inhibitors Protect PC12 Cells against 6-Hydroxydopamine- and Rotenone-Induced Oxidative Stress

por Elsherbeny, Mohamed H., Kim, Jushin, Gouda, Noha A., Gotina, Lizaveta, Cho, Jungsook, Pae, Ae Nim, Lee, Kyeong, Park, Ki Duk, Elkamhawy, Ahmed, Roh, Eun Joo
Publicado 2021

Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis

por Won, Woojin, Choi, Hyun-Ji, Yoo, Ji-Young, Kim, Daeun, Kim, Tai Young, Ju, YeonHa, Park, Ki Duk, Lee, Hyunbeom, Jung, Sang Youn, Lee, C. Justin
Publicado 2022

Substituted N-(Biphenyl-4′-yl)methyl (R)-2-Acetamido-3-methoxypropionamides: Potent Anticonvulsants That Affect Frequency (Use) Dependence and Slow Inactivation of Sodium Channels...

por Lee, Hyosung, Park, Ki Duk, Torregrosa, Robert, Yang, Xiao-Fang, Dustrude, Erik T., Wang, Yuying, Wilson, Sarah M., Barbosa, Cindy, Xiao, Yucheng, Cummins, Theodore R., Khanna, Rajesh, Kohn, Harold
Publicado 2014

Synthesis and Evaluation of Serinolamide Derivatives as Sphingosine-1-Phosphate-1 (S1P(1)) Receptor Agonists

por Park, Sun Jun, Kim, Jushin, Kim, Jaehwan, Kim, Yoowon, Lee, Elijah Hwejin, Kim, Hyeon Jeong, Kim, Siwon, Kim, Byungeun, Kim, Rium, Choi, Ji Won, Park, Jong-Hyun, Park, Ki Duk
Publicado 2022

Neuronal CRMP2 phosphorylation inhibition by the flavonoid, naringenin, contributes to the reversal of spinal sensitization and arthritic pain improvement

por Jiang, Yue-Peng, Wang, Song, Lai, Wei-Dong, Wu, Xue-Qing, Jin, Yan, Xu, Zheng-Hao, Moutal, Aubin, Khanna, Rajesh, Park, Ki Duk, Shan, Zhi-Ming, Wen, Cheng-Ping, Yu, Jie
Publicado 2022

Positional scanning of natural product hispidol’s ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for managemen...

por Hassan, Ahmed H. E., Kim, Hyeon Jeong, Gee, Min Sung, Park, Jong-Hyun, Jeon, Hye Rim, Lee, Cheol Jung, Choi, Yeonwoo, Moon, Suyeon, Lee, Danbi, Lee, Jong Kil, Park, Ki Duk, Lee, Yong Sup
Publicado 2022