The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62

por Ha, Jihoon, Kim, Minbeom, Seo, Dongyeob, Park, Jin Seok, Lee, Jaewon, Lee, Jinjoo, Park, Seok Hee
Publicado 2020

The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway

por Seo, Dongyeob, Jung, Su Myung, Park, Jin Seok, Lee, Jaewon, Ha, Jihoon, Kim, Minbeom, Park, Seok Hee
Publicado 2019

Site-specific monoubiquitination downregulates Rab5 by disrupting effector binding and guanine nucleotide conversion

por Shin, Donghyuk, Na, Wooju, Lee, Ji-Hyung, Kim, Gyuhee, Baek, Jiseok, Park, Seok Hee, Choi, Cheol Yong, Lee, Sangho
Publicado 2017

Anti-inflammatory mechanisms of suppressors of cytokine signaling target ROS via NRF-2/thioredoxin induction and inflammasome activation in macrophages

por Kim, Ga-Young, Jeong, Hana, Yoon, Hye-Young, Yoo, Hye-Min, Lee, Jae Young, Park, Seok Hee, Lee, Choong-Eun
Publicado 2020

Galectin-3 Facilitates Cell Motility in Gastric Cancer by Up-Regulating Protease-Activated Receptor-1(PAR-1) and Matrix Metalloproteinase-1(MMP-1)

por Kim, Seok-Jun, Shin, Ji-Young, Lee, Kang-Duck, Bae, Young-Ki, Choi, Il-Ju, Park, Seok Hee, Chun, Kyung-Hee
Publicado 2011

A novel SMAD6 variant in a patient with severely calcified bicuspid aortic valve and thoracic aortic aneurysm

por Park, Jong Eun, Park, Jin Seok, Jang, Shin Yi, Park, Seok Hee, Kim, Jong‐Won, Ki, Chang‐Seok, Kim, Duk‐Kyung
Publicado 2019

SOCS3 Attenuates Dexamethasone-Induced M2 Polarization by Down-Regulation of GILZ via ROS- and p38 MAPK-Dependent Pathways

por Jeong, Hana, Yoon, Hyeyoung, Lee, Yerin, Kim, Jun Tae, Yang, Moses, Kim, Gayoung, Jung, Bom, Park, Seok Hee, Lee, Choong-Eun
Publicado 2022

The deubiquitinating enzyme, ubiquitin‐specific peptidase 50, regulates inflammasome activation by targeting the ASC adaptor protein

por Lee, Jae Young, Seo, Dongyeob, You, Jiyeon, Chung, Sehee, Park, Jin Seok, Lee, Ji‐Hyung, Jung, Su Myung, Lee, Youn Sook, Park, Seok Hee
Publicado 2017

Inhibition of TGF-β signalling in combination with nal-IRI plus 5-Fluorouracil/Leucovorin suppresses invasion and prolongs survival in pancreatic tumour mouse models

por Hong, Eunji, Park, Sujin, Ooshima, Akira, Hong, Chang Pyo, Park, Jinah, Heo, Jin Sun, Lee, Siyoung, An, Haein, Kang, Jin Muk, Park, Seok Hee, Park, Joon Oh, Kim, Seong-Jin
Publicado 2020

Metastasis Risk Assessment Using BAG2 Expression by Cancer-Associated Fibroblast and Tumor Cells in Patients with Breast Cancer

por Yoon, Chang-Ik, Ahn, Sung-Gwe, Cha, Yoon-Jin, Kim, Dooreh, Bae, Soong-June, Lee, Ji-Hyung, Ooshima, Akira, Yang, Kyung-Min, Park, Seok-Hee, Kim, Seong-Jin, Jeong, Joon
Publicado 2021

A Reciprocal Role of the Smad4‐Taz Axis in Osteogenesis and Adipogenesis of Mesenchymal Stem Cells

por Park, Jin Seok, Kim, Minbeom, Song, No‐Joon, Kim, Jun‐Hyeong, Seo, Dongyeob, Lee, Ji‐Hyung, Jung, Su Myung, Lee, Jae Young, Lee, Jaewon, Lee, Youn Sook, Park, Kye Won, Park, Seok Hee
Publicado 2018

TRIM24-RIP3 axis perturbation accelerates osteoarthritis pathogenesis

por Jeon, Jimin, Noh, Hyun-Jin, Lee, Hyemi, Park, Han-Hee, Ha, Yu-Jin, Park, Seok Hee, Lee, Haeseung, Kim, Seok-Jung, Kang, Ho Chul, Eyun, Seong-il, Yang, Siyoung, Kim, You-Sun
Publicado 2020

Serum amyloid A promotes emphysema by triggering the reciprocal activation of neutrophils and ILC3s

por Kim, Jihyun, Shin, Jae Woo, Lee, Hyun‐Jun, Kim, Ji Hyung, Choi, Sun Mi, Lee, Chang‐Hoon, Kang, Hye Ryun, Park, Seok Hee, Bae, Yoe‐Sik, Chung, Doo Hyun, Kim, Hye Young
Publicado 2021

Combination treatment of T1-44, a PRMT5 inhibitor with Vactosertib, an inhibitor of TGF-β signaling, inhibits invasion and prolongs survival in a mouse model of pancreatic tumors

por Hong, Eunji, Barczak, Wojciech, Park, Sujin, Heo, Jin Sun, Ooshima, Akira, Munro, Shonagh, Hong, Chang Pyo, Park, Jinah, An, Haein, Park, Joon Oh, Park, Seok Hee, La Thangue, Nick B., Kim, Seong-Jin
Publicado 2023

TRAF6 Mediates IL-1β/LPS-Induced Suppression of TGF-β Signaling through Its Interaction with the Type III TGF-β Receptor

por Lim, Seunghwan, Bae, Eunjin, Kim, Hae-Suk, Kim, Tae-Aug, Byun, Kyunghee, Kim, Byungchul, Hong, Suntaek, Im, Jong Pil, Yun, Chohee, Lee, Bona, Lee, Bonghee, Park, Seok Hee, Letterio, John, Kim, Seong-Jin
Publicado 2012

Inhibition of lethal inflammatory responses through the targeting of membrane-associated Toll-like receptor 4 signaling complexes with a Smad6-derived peptide

por Lee, Youn Sook, Park, Jin Seok, Jung, Su Myung, Kim, Sang-Doo, Kim, Jun Hwan, Lee, Jae Young, Jung, Kyeong Cheon, Mamura, Mizuko, Lee, Sangho, Kim, Seong-Jin, Bae, Yoe-Sik, Park, Seok Hee
Publicado 2015

High A20 expression negatively impacts survival in patients with breast cancer

por Yoon, Chang Ik, Ahn, Sung Gwe, Bae, Soong June, Shin, Yun Jin, Cha, Chihwan, Park, So Eun, Lee, Ji-Hyung, Ooshima, Akira, Lee, Hye Sun, Yang, Kyung-Min, Kim, Seong-Jin, Park, Seok Hee, Jeong, Joon
Publicado 2019

Therapeutic effects of mouse bone marrow-derived clonal mesenchymal stem cells in a mouse model of inflammatory bowel disease

por Park, Jin Seok, Yi, Tac-Ghee, Park, Jong-Min, Han, Young Min, Kim, Jun-Hyung, Shin, Dong-Hee, Tak, Seon Ji, Lee, Kyuheon, Lee, Youn Sook, Jeon, Myung-Shin, Hahm, Ki-Baik, Song, Sun U, Park, Seok Hee
Publicado 2015

Peli3 ablation ameliorates acetaminophen-induced liver injury through inhibition of GSK3β phosphorylation and mitochondrial translocation

por Lee, Jaewon, Ha, Jihoon, Kim, Jun-Hyeong, Seo, Dongyeob, Kim, Minbeom, Lee, Yerin, Park, Seong Shil, Choi, Dahee, Park, Jin Seok, Lee, Young Jae, Yang, Siyoung, Yang, Kyung-Min, Jung, Su Myung, Hong, Suntaek, Koo, Seung-Hoi, Bae, Yong-Soo, Kim, Seong-Jin, Park, Seok Hee
Publicado 2023

Protein and lipid MALDI profiles classify breast cancers according to the intrinsic subtype

por Kang, Han Sung, Lee, Seok Cheol, Park, Young Seung, Jeon, Young Eun, Lee, Jeong Hwa, Jung, So-Youn, Park, In Hae, Jang, Seok Hoon, Park, Hye Min, Yoo, Chong Woo, Park, Seok Hee, Han, Sang Yun, Kim, Kwang Pyo, Kim, Young Hwan, Ro, Jungsil, Kim, Hark Kyun
Publicado 2011