Reciprocal allostery arising from a bienzyme assembly controls aromatic amino acid biosynthesis in Prevotella nigrescens

por Bai, Yu, Parker, Emily J.
Publicado 2021

Expression, Purification, and Characterisation of Dehydroquinate Synthase from Pyrococcus furiosus

por Negron, Leonardo, Patchett, Mark L., Parker, Emily J.
Publicado 2011

Conformational interdomain flexibility in a bacterial α-isopropylmalate synthase is necessary for leucine biosynthesis

por Bai, Yu, Jiao, Wanting, Vörster, Jan, Parker, Emily J.
Publicado 2022

Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using ᴅ-Amino Acids

por Reichau, Sebastian, Blackmore, Nicola J., Jiao, Wanting, Parker, Emily J.
Publicado 2016

Structure, mechanism and inhibition of anthranilate phosphoribosyltransferase

por Scully, Thomas W., Jiao, Wanting, Mittelstädt, Gerd, Parker, Emily J.
Publicado 2023

Quaternary structure is an essential component that contributes to the sophisticated allosteric regulation mechanism in a key enzyme from Mycobacterium tuberculosis

por Jiao, Wanting, Blackmore, Nicola J., Nazmi, Ali Reza, Parker, Emily J.
Publicado 2017

Reactivity and mechanism in chemical and synthetic biology

por Richards, Nigel G. J., Bearne, Stephen L., Goto, Yuki, Parker, Emily J.
Publicado 2023

The Functional Unit of Neisseria meningitidis 3-Deoxy-ᴅ-Arabino-Heptulosonate 7-Phosphate Synthase Is Dimeric

por Cross, Penelope J., Heyes, Logan C., Zhang, Shiwen, Nazmi, Ali Reza, Parker, Emily J.
Publicado 2016

Draft Genome Sequence of the Filamentous Fungus Hypoxylon pulicicidum ATCC 74245

por Nicholson, Matthew J., Van de Bittner, Kyle C., Ram, Arvina, Bustamante, Leyla Y., Scott, Barry, Parker, Emily J.
Publicado 2018

Biosynthesis of Nodulisporic Acids: A Multifunctional Monooxygenase Delivers a Complex and Highly Branched Array

por Richardson, Alistair T., Cameron, Rosannah C., Stevenson, Luke J., Singh, A. Jonathan, Lukito, Yonathan, Berry, Daniel, Nicholson, Matthew J., Parker, Emily J.
Publicado 2022

Structural and functional characterisation of the entry point to pyocyanin biosynthesis in Pseudomonas aeruginosa defines a new 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase...

por Sterritt, Oliver W., Lang, Eric J.M., Kessans, Sarah A., Ryan, Timothy M., Demeler, Borries, Jameson, Geoffrey B., Parker, Emily J.
Publicado 2018

Structure of the NDH-2 – HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors

por Petri, Jessica, Shimaki, Yosuke, Jiao, Wanting, Bridges, Hannah R., Russell, Euan R., Parker, Emily J., Aragão, David, Cook, Gregory M., Nakatani, Yoshio
Publicado 2018

Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups

por Evans, Genevieve L., Furkert, Daniel P., Abermil, Nacim, Kundu, Preeti, de Lange, Katrina M., Parker, Emily J., Brimble, Margaret A., Baker, Edward N., Lott, J. Shaun
Publicado 2017

Deletion and Gene Expression Analyses Define the Paxilline Biosynthetic Gene Cluster in Penicillium paxilli

por Scott, Barry, Young, Carolyn A., Saikia, Sanjay, McMillan, Lisa K., Monahan, Brendon J., Koulman, Albert, Astin, Jonathan, Eaton, Carla J., Bryant, Andrea, Wrenn, Ruth E., Finch, Sarah C., Tapper, Brian A., Parker, Emily J., Jameson, Geoffrey B.
Publicado 2013

Incorporation of SARS-CoV-2 spike NTD to RBD protein vaccine improves immunity against viral variants

por Montgomerie, Isabelle, Bird, Thomas W., Palmer, Olga R., Mason, Ngarangi C., Pankhurst, Theresa E., Lawley, Blair, Hernández, Leonor C., Harfoot, Rhodri, Authier-Hall, Astrid, Anderson, Danielle E., Hilligan, Kerry L., Buick, Kaitlin H., Mbenza, Naasson M., Mittelstädt, Gerd, Maxwell, Samara, Sinha, Shubhra, Kuang, Joanna, Subbarao, Kanta, Parker, Emily J., Sher, Alan, Hermans, Ian F., Ussher, James E., Quiñones-Mateu, Miguel E., Comoletti, Davide, Connor, Lisa M.
Publicado 2023

Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals

por Lacaze, Paul, Sebra, Robert, Riaz, Moeen, Tiller, Jane, Revote, Jerico, Phung, James, Parker, Emily J, Orchard, Suzanne G, Lockery, Jessica E, Wolfe, Rory, Strahl, Maya, Wang, Ying C, Chen, Rong, Sisco, Daniel, Arnold, Todd, Thompson, Bryony A, Buchanan, Daniel D, Macrae, Finlay A, James, Paul A, Abhayaratna, Walter P, Lockett, Trevor J, Gibbs, Peter, Tonkin, Andrew M, Nelson, Mark R, Reid, Christopher M, Woods, Robyn L, Murray, Anne M, Winship, Ingrid, McNeil, John J, Schadt, Eric
Publicado 2020