Comparative Genomics for the Elucidation of Multidrug Resistance in Candida lusitaniae

por Kannan, Abhilash, Asner, Sandra A., Trachsel, Emilie, Kelly, Steve, Parker, Josie, Sanglard, Dominique
Publicado 2019

Erratum for Kannan et al., “Comparative Genomics for the Elucidation of Multidrug Resistance in Candida lusitaniae”

por Kannan, Abhilash, Asner, Sandra A., Trachsel, Emilie, Kelly, Steve, Parker, Josie, Sanglard, Dominique
Publicado 2020

A prospective, masked, randomized, controlled superiority study comparing the incidence of corneal injury following general anesthesia in dogs with two methods of corneal protectio...

por Ioannides, Joy, Parker, Josie, Kumaratunga, Vim, Preston, Juliette, Donaldson, David, MacFarlane, Paul, Hartley, Claudia
Publicado 2022

Molecular Characterization and Sterol Profiles Identify Nonsynonymous Mutations in ERG2 as a Major Mechanism Conferring Reduced Susceptibility to Amphotericin B in Candida kefyr

por Asadzadeh, Mohammad, Alfouzan, Wadha, Parker, Josie E., Meis, Jacques F., Kelly, Steven L., Joseph, Leena, Ahmad, Suhail
Publicado 2023

Mutations in hmg1, Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus

por Rybak, Jeffrey M., Ge, Wenbo, Wiederhold, Nathan P., Parker, Josie E., Kelly, Steven L., Rogers, P. David, Fortwendel, Jarrod R.
Publicado 2019

Cytochrome P450 168A1 from Pseudomonas aeruginosa is involved in the hydroxylation of biologically relevant fatty acids

por Price, Claire L., Warrilow, Andrew G. S., Rolley, Nicola J., Parker, Josie E., Thoss, Vera, Kelly, Diane E., Corcionivoschi, Nicolae, Kelly, Steven L.
Publicado 2022

Analysis of cytochrome b(5) reductase-mediated metabolism in the phytopathogenic fungus Zymoseptoria tritici reveals novel functionalities implicated in virulence

por Derbyshire, Mark C., Michaelson, Louise, Parker, Josie, Kelly, Steven, Thacker, Urvashi, Powers, Stephen J., Bailey, Andy, Hammond-Kosack, Kim, Courbot, Mikael, Rudd, Jason
Publicado 2015

Proper Sterol Distribution Is Required for Candida albicans Hyphal Formation and Virulence

por McCourt, Paula, Liu, Hsing-Yin, Parker, Josie E., Gallo-Ebert, Christina, Donigan, Melissa, Bata, Adam, Giordano, Caroline, Kelly, Steven L., Nickels, Joseph T.
Publicado 2016

Target Abundance-Based Fitness Screening (TAFiS) Facilitates Rapid Identification of Target-Specific and Physiologically Active Chemical Probes

por Butts, Arielle, DeJarnette, Christian, Peters, Tracy L., Parker, Josie E., Kerns, Morgan E., Eberle, Karen E., Kelly, Steve L., Palmer, Glen E.
Publicado 2017

The Evolution of Azole Resistance in Candida albicans Sterol 14α-Demethylase (CYP51) through Incremental Amino Acid Substitutions

por Warrilow, Andrew G., Nishimoto, Andrew T., Parker, Josie E., Price, Claire L., Flowers, Stephanie A., Kelly, Diane E., Rogers, P. David, Kelly, Steven L.
Publicado 2019

Small‐Molecule Inhibitors Targeting Sterol 14α‐Demethylase (CYP51): Synthesis, Molecular Modelling and Evaluation Against Candida albicans

por Binjubair, Faizah A., Parker, Josie E., Warrilow, Andrew G., Puri, Kalika, Braidley, Peter J., Tatar, Esra, Kelly, Steven L., Kelly, Diane E., Simons, Claire
Publicado 2020

Titration of C-5 Sterol Desaturase Activity Reveals Its Relationship to Candida albicans Virulence and Antifungal Susceptibility Is Dependent upon Host Immune Status

por Regan, Jessica, DeJarnette, Christian, Luna-Tapia, Arturo, Parker, Josie E., Reitler, Parker, Barnett, Stacey, Tucker, Katie M., Kelly, Steven L., Palmer, Glen E.
Publicado 2022

Molecular Modelling of the Emergence of Azole Resistance in Mycosphaerella graminicola

por Mullins, Jonathan G. L., Parker, Josie E., Cools, Hans J., Togawa, Roberto C., Lucas, John A., Fraaije, Bart A., Kelly, Diane E., Kelly, Steven L.
Publicado 2011

Loss of Upc2p-Inducible ERG3 Transcription Is Sufficient To Confer Niche-Specific Azole Resistance without Compromising Candida albicans Pathogenicity

por Luna-Tapia, Arturo, Willems, Hubertine M. E., Parker, Josie E., Tournu, Hélène, Barker, Katherine S., Nishimoto, Andrew T., Rogers, P. David, Kelly, Steven L., Peters, Brian M., Palmer, Glen E.
Publicado 2018

Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma

por Griffiths, William J., Crick, Peter J., Meljon, Anna, Theofilopoulos, Spyridon, Abdel-Khalik, Jonas, Yutuc, Eylan, Parker, Josie E., Kelly, Diane E., Kelly, Steven L., Arenas, Ernest, Wang, Yuqin
Publicado 2019

The sterol C-24 methyltransferase encoding gene, erg6, is essential for viability of Aspergillus species

por Xie, Jinhong, Rybak, Jeffrey M., Martin-Vicente, Adela, Guruceaga, Xabier, Thorn, Harrison I., Nywening, Ashley V., Ge, Wenbo, Parker, Josie E., Kelly, Steven L., Rogers, P. David, Fortwendel, Jarrod R.
Publicado 2023

Loss-of-Function ROX1 Mutations Suppress the Fluconazole Susceptibility of upc2AΔ Mutation in Candida glabrata, Implicating Additional Positive Regulators of Ergosterol Biosynthesi...

por Ollinger, Tomye L., Vu, Bao, Murante, Daniel, Parker, Josie E., Simonicova, Lucia, Doorley, Laura, Stamnes, Mark A., Kelly, Steven L., Rogers, P. David, Moye-Rowley, W. Scott, Krysan, Damian J.
Publicado 2021

Discovery of a Novel Dual Fungal CYP51/Human 5-Lipoxygenase Inhibitor: Implications for Anti-Fungal Therapy

por Hoobler, Eric K., Rai, Ganesha, Warrilow, Andrew G. S., Perry, Steven C., Smyrniotis, Christopher J., Jadhav, Ajit, Simeonov, Anton, Parker, Josie E., Kelly, Diane E., Maloney, David J., Kelly, S. L., Holman, Theodore R.
Publicado 2013

Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa

por Warrilow, Andrew G. S., Price, Claire L., Parker, Josie E., Rolley, Nicola J., Smyrniotis, Christopher J., Hughes, David D., Thoss, Vera, Nes, W. David, Kelly, Diane E., Holman, Theodore R., Kelly, Steven L.
Publicado 2016

Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris

por Rybak, Jeffrey M., Muñoz, José F., Barker, Katherine S., Parker, Josie E., Esquivel, Brooke D., Berkow, Elizabeth L., Lockhart, Shawn R., Gade, Lalitha, Palmer, Glen E., White, Theodore C., Kelly, Steve L., Cuomo, Christina A., Rogers, P. David
Publicado 2020