Benchmarking of Scale-X Bioreactor System in Lentiviral and Adenoviral Vector Production

por Leinonen, Hanna M., Lepola, Saana, Lipponen, Eevi M., Heikura, Tommi, Koponen, Tiina, Parker, Nigel, Ylä-Herttuala, Seppo, Lesch, Hanna P.
Publicado 2020

Transcriptomics uncovers substantial variability associated with alterations in manufacturing processes of macrophage cell therapy products

por Gurvich, Olga L., Puttonen, Katja A., Bailey, Aubrey, Kailaanmäki, Anssi, Skirdenko, Vita, Sivonen, Minna, Pietikäinen, Sanna, Parker, Nigel R., Ylä-Herttuala, Seppo, Kekarainen, Tuija
Publicado 2020

Inhibition of urothelial carcinoma through targeted type I interferon-mediated immune activation

por Plote, Devin, Choi, Woonyoung, Mokkapati, Sharada, Sundi, Debasish, Ferguson, James E, Duplisea, Jon, Parker, Nigel R., Yla-Herttuala, Seppo, Committee, SUO CTC Bladder, McConkey, David, Schluns, Kimberly S., Dinney, Colin P.
Publicado 2019

Development of Large-Scale Downstream Processing for Lentiviral Vectors

por Valkama, Anniina J., Oruetxebarria, Igor, Lipponen, Eevi M., Leinonen, Hanna M., Käyhty, Piia, Hynynen, Heidi, Turkki, Vesa, Malinen, Joonas, Miinalainen, Tuukka, Heikura, Tommi, Parker, Nigel R., Ylä-Herttuala, Seppo, Lesch, Hanna P.
Publicado 2020

Preclinical Proof-of-Concept, Analytical Development, and Commercial Scale Production of Lentiviral Vector in Adherent Cells

por Leinonen, Hanna M., Lipponen, Eevi M., Valkama, Anniina J., Hynynen, Heidi, Oruetxebarria, Igor, Turkki, Vesa, Olsson, Venla, Kurkipuro, Jere, Samaranayake, Haritha, Määttä, Ann-Marie, Parker, Nigel R., Ylä-Herttuala, Seppo, Lesch, Hanna P.
Publicado 2019

Lentiviral interferon: A novel method for gene therapy in bladder cancer

por Mokkapati, Sharada, Narayan, Vikram M., Manyam, Ganiraju C., Lim, Amy H., Duplisea, Jonathan J., Kokorovic, Andrea, Miest, Tanner S., Mitra, Anirban P., Plote, Devin, Anand, Selvalakshmi Selvaraj, Metcalfe, Michael J., Dunner, Kenneth, Johnson, Burles A., Czerniak, Bogdan A., Nieminen, Tiina, Heikura, Tommi, Yla-Herttuala, Seppo, Parker, Nigel R., Schluns, Kimberley S., McConkey, David J., Dinney, Colin P.
Publicado 2022