IBD BioResource: an open-access platform of 25 000 patients to accelerate research in Crohn’s and Colitis

por Parkes, Miles
Publicado 2019

Diverticular disease: picking pockets and population biobanks

por Weersma, Rinse K, Parkes, Miles
Publicado 2019

Moving towards more patient-centred clinical trials in IBD

por Noor, Nurulamin M., Parkes, Miles, Raine, Tim
Publicado 2021

Generation of primary human intestinal T cell transcriptomes reveals differential expression at genetic risk loci for immune-mediated disease

por Raine, Tim, Liu, Jimmy Z, Anderson, Carl A, Parkes, Miles, Kaser, Arthur
Publicado 2015

Mitochondrial neurogastrointestinal encephalopathy: a clinicopathological mimic of Crohn’s disease

por Patel, Ravi, Coulter, Lucia Lee, Rimmer, Joanna, Parkes, Miles, Chinnery, Patrick Francis, Swift, Oscar
Publicado 2019

Acetarsol Suppositories: Effective Treatment for Refractory Proctitis in a Cohort of Patients with Inflammatory Bowel Disease

por Kiely, Christopher J., Clark, Angela, Bhattacharyya, Joya, Moran, Gordon W., Lee, James C., Parkes, Miles
Publicado 2018

Thiopurine monotherapy is effective in ulcerative colitis but significantly less so in Crohn’s disease: long-term outcomes for 11 928 patients in the UK inflammatory bowel disease...

por Stournaras, Evangelos, Qian, Wendi, Pappas, Apostolos, Hong, You Yi, Shawky, Rasha, Raine, Tim, Parkes, Miles
Publicado 2021

A Comparison of Outcomes for Adults and Children Undergoing Resection for Inflammatory Bowel Disease: Is There a Difference?

por Mcmullin, Christine M., Morton, Jonathan, Vickramarajah, Saranya, Cameron, Ewen, Parkes, Miles, Torrente, Franco, Heuschkel, Robert, Carroll, Nicholas, Davies, R. Justin
Publicado 2014

Intestinal APCs of the endogenous nanomineral pathway fail to express PD-L1 in Crohn’s disease

por Robertson, Jack, Haas, Carolin T., Pele, Laetitia C., Monie, Tom P., Charalambos, Charles, Parkes, Miles, Hewitt, Rachel E., Powell, Jonathan J.
Publicado 2016

Single-cell genomics for resolution of conserved bacterial genes and mobile genetic elements of the human intestinal microbiota using flow cytometry

por Lawrence, Dylan, Campbell, Danielle E., Schriefer, Lawrence A., Rodgers, Rachel, Walker, Forrest C., Turkin, Marissa, Droit, Lindsay, Parkes, Miles, Handley, Scott A., Baldridge, Megan T.
Publicado 2022

DNA Methylation Analysis in the Intestinal Epithelium—Effect of Cell Separation on Gene Expression and Methylation Profile

por Jenke, Andreas C., Postberg, Jan, Raine, Timothy, Nayak, Komal M., Molitor, Malte, Wirth, Stefan, Kaser, Arthur, Parkes, Miles, Heuschkel, Robert B., Orth, Valerie, Zilbauer, Matthias
Publicado 2013

Genome-wide rare copy number variation screening in ulcerative colitis identifies potential susceptibility loci

por Saadati, Hamid Reza, Wittig, Michael, Helbig, Ingo, Häsler, Robert, Anderson, Carl A., Mathew, Christopher G., Kupcinskas, Limas, Parkes, Miles, Karlsen, Tom Hemming, Rosenstiel, Philip, Schreiber, Stefan, Franke, Andre
Publicado 2016

The Impact of NOD2 Variants on Fecal Microbiota in Crohn’s Disease and Controls Without Gastrointestinal Disease

por Kennedy, Nicholas A, Lamb, Christopher A, Berry, Susan H, Walker, Alan W, Mansfield, John, Parkes, Miles, Simpkins, Rachel, Tremelling, Mark, Nutland, Sarah, Parkhill, Julian, Probert, Chris, Hold, Georgina L, Lees, Charlie W
Publicado 2018

A blood-based prognostic biomarker in IBD

por Biasci, Daniele, Lee, James C, Noor, Nurulamin M, Pombal, Diana R, Hou, Monica, Lewis, Nina, Ahmad, Tariq, Hart, Ailsa, Parkes, Miles, McKinney, Eoin F, Lyons, Paul A, Smith, Kenneth G C
Publicado 2019

Trial summary and protocol for a phase II randomised placebo-controlled double-blinded trial of Interleukin 1 blockade in Acute Severe Colitis: the IASO trial

por Thomas, Martin Geoffrey, Bayliss, Carrie, Bond, Simon, Dowling, Francis, Galea, James, Jairath, Vipul, Lamb, Christopher, Probert, Christopher, Timperley-Preece, Elizabeth, Watson, Alastair, Whitehead, Lynne, Williams, John G, Parkes, Miles, Kaser, Arthur, Raine, Tim
Publicado 2019

PRedicting Outcomes For Crohn’s dIsease using a moLecular biomarkEr (PROFILE): protocol for a multicentre, randomised, biomarker-stratified trial

por Parkes, Miles, Noor, Nurulamin M, Dowling, Francis, Leung, Harvey, Bond, Simon, Whitehead, Lynne, Upponi, Sara, Kinnon, Paul, Sandham, Andrew P, Lyons, Paul A, McKinney, Eoin F, Smith, Kenneth G C, Lee, James C
Publicado 2018

Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease

por Dart, Robin J, Zlatareva, Iva, Vantourout, Pierre, Theodoridis, Efstathios, Amar, Ariella, Kannambath, Shichina, East, Philip, Recaldin, Timothy, Mansfield, John C, Lamb, Christopher A, Parkes, Miles, Irving, Peter M, Prescott, Natalie J, Hayday, Adrian C
Publicado 2023

The Impact of NOD2 Genetic Variants on the Gut Mycobiota in Crohn’s Disease Patients in Remission and in Individuals Without Gastrointestinal Inflammation

por Nelson, Andrew, Stewart, Christopher J, Kennedy, Nicholas A, Lodge, John K, Tremelling, Mark, Probert, Chris S, Parkes, Miles, Mansfield, John C, Smith, Darren L, Hold, Georgina L, Lees, Charlie W, Bridge, Simon H, Lamb, Christopher A
Publicado 2020

A Crohn’s Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling

por Goldberg, Rimma, Clough, Jennie N, Roberts, Luke B, Sanchez, Jenifer, Kordasti, Shahram, Petrov, Nedyalko, Hertweck, Arnulf, Lorenc, Anna, Jackson, Ian, Tasker, Scott, Appios, Anna, Omer, Omer, Parkes, Miles, Prescott, Natalie, Jenner, Richard G, Irving, Peter M, Lord, Graham M
Publicado 2021

Two microbiota subtypes identified in irritable bowel syndrome with distinct responses to the low FODMAP diet

por Vervier, Kevin, Moss, Stephen, Kumar, Nitin, Adoum, Anne, Barne, Meg, Browne, Hilary, Kaser, Arthur, Kiely, Christopher J, Neville, B Anne, Powell, Nina, Raine, Tim, Stares, Mark D, Zhu, Ana, De La Revilla Negro, Juan, Lawley, Trevor D, Parkes, Miles
Publicado 2022